Receptor occupancy assessment by flow cytometry as a pharmacodynamic biomarker in biopharmaceutical development

por Liang, Meina, Schwickart, Martin, Schneider, Amy K., Vainshtein, Inna, Del Nagro, Christopher, Standifer, Nathan, Roskos, Lorin K.
Publicado 2015

Subcutaneous versus Intravenous Administration of Rituximab: Pharmacokinetics, CD20 Target Coverage and B-Cell Depletion in Cynomolgus Monkeys

por Mao, Cheng-Ping, Brovarney, Martin R., Dabbagh, Karim, Birnböck, Herbert F., Richter, Wolfgang F., Del Nagro, Christopher J.
Publicado 2013

Evaluation of assay interference and interpretation of CXCR4 receptor occupancy results in a preclinical study with MEDI3185, a fully human antibody to CXCR4

por Schwickart, Martin, Chavez, Carlos, Henderson, Simon, Vainshtein, Inna, Standifer, Nathan, DelNagro, Christopher, Mehrzai, Freshta, Schneider, Amy, Roskos, Lorin, Liang, Meina
Publicado 2015

Development and validation of a multiplex immunoassay for the simultaneous quantification of type-specific IgG antibodies to E6/E7 oncoproteins of HPV16 and HPV18

por Layman, Hans, Rickert, Keith W., Wilson, Susan, Aksyuk, Anastasia A., Dunty, Jill M., Natrakul, Dusit, Swaminathan, Nithya, DelNagro, Christopher J.
Publicado 2020

Chk1 inhibition in p53-deficient cell lines drives rapid chromosome fragmentation followed by caspase-independent cell death

por Del Nagro, Christopher J, Choi, Jonathan, Xiao, Yang, Rangell, Linda, Mohan, Sankar, Pandita, Ajay, Zha, Jiping, Jackson, Peter K, O’Brien, Thomas
Publicado 2014