Determinants of IGF-II influencing stability, receptor binding and activation

por Blyth, Andrew, Ortiz, Michael, Merriman, Allanah, Delaine, Carlie, Forbes, Briony
Publicado 2022

Total Chemical Synthesis of Palmitoyl-Conjugated Insulin

por Liu, Mengjie, Li, Qingyang, Delaine, Carlie, Wu, Hongkang, Arsenakis, Yanni, White, Barbara F., Forbes, Briony E., Chandrashekar, Chaitra, Hossain, Mohammed Akhter
Publicado 2023

Understanding the Mechanism of Insulin and Insulin-Like Growth Factor (IGF) Receptor Activation by IGF-II

por Alvino, Clair L., Ong, Shee Chee, McNeil, Kerrie A., Delaine, Carlie, Booker, Grant W., Wallace, John C., Forbes, Briony E.
Publicado 2011

Minimizing Mitogenic Potency of Insulin Analogues Through Modification of a Disulfide Bond

por Ong, Shee Chee, Belgi, Alessia, Merriman, Allanah L., Delaine, Carlie A., van Lierop, Bianca, Andrikopoulos, Sofianos, Robinson, Andrea J., Forbes, Briony E.
Publicado 2022

How insulin-like growth factor I binds to a hybrid insulin receptor type 1 insulin-like growth factor receptor

por Xu, Yibin, Margetts, Mai B., Venugopal, Hari, Menting, John G., Kirk, Nicholas S., Croll, Tristan I., Delaine, Carlie, Forbes, Briony E., Lawrence, Michael C.
Publicado 2022

Insulin in motion: The A6-A11 disulfide bond allosterically modulates structural transitions required for insulin activity

por van Lierop, Bianca, Ong, Shee Chee, Belgi, Alessia, Delaine, Carlie, Andrikopoulos, Sofianos, Haworth, Naomi L., Menting, John G., Lawrence, Michael C., Robinson, Andrea J., Forbes, Briony E.
Publicado 2017

How IGF-II Binds to the Human Type 1 Insulin-like Growth Factor Receptor

por Xu, Yibin, Kirk, Nicholas S., Venugopal, Hariprasad, Margetts, Mai B., Croll, Tristan I., Sandow, Jarrod J., Webb, Andrew I., Delaine, Carlie A., Forbes, Briony E., Lawrence, Michael C.
Publicado 2020

How ligand binds to the type 1 insulin-like growth factor receptor

por Xu, Yibin, Kong, Geoffrey K.-W., Menting, John G., Margetts, Mai B., Delaine, Carlie A., Jenkin, Lauren M., Kiselyov, Vladislav V., De Meyts, Pierre, Forbes, Briony E., Lawrence, Michael C.
Publicado 2018

Identification, Synthesis, Conformation and Activity of an Insulin-like Peptide from a Sea Anemone

por Mitchell, Michela L., Hossain, Mohammed Akhter, Lin, Feng, Pinheiro-Junior, Ernesto L., Peigneur, Steve, Wai, Dorothy C. C., Delaine, Carlie, Blyth, Andrew J., Forbes, Briony E., Tytgat, Jan, Wade, John D., Norton, Raymond S.
Publicado 2021

A structurally minimized yet fully active insulin based on cone-snail venom insulin principles

por Xiong, Xiaochun, Menting, John G., Disotuar, Maria M., Smith, Nicholas A., Delaine, Carlie, Ghabash, Gabrielle, Agrawal, Rahul, Wang, Xiaomin, He, Xiao, Fisher, Simon J., MacRaild, Christopher A., Norton, Raymond S., Gajewiak, Joanna, Forbes, Briony E., Smith, Brian J., Safavi-Hemami, Helena, Olivera, Baldomero, Lawrence, Michael C., Hung-Chieh Chou, Danny
Publicado 2020

Symmetric and Asymmetric Receptor Conformation Continuum induced by a Novel Insulin

por Xiong, Xiaochun, Blakely, Alan, Kim, Jin Hwan, Menting, John G., Schäfer, Ingmar B., Schubert, Heidi L., Agrawal, Rahul, Gutmann, Theresia, Delaine, Carlie, Zhang, Yi Wolf, Artik, Gizem Olay, Merriman, Allanah, Eckert, Debbie, Lawrence, Michael C., Coskun, Ünal, Fisher, Simon J., Forbes, Briony E., Safavi-Hemami, Helena, Hill, Christopher P., Chou, Danny Hung-Chieh
Publicado 2022