Sugar, fat, and protein: new insights into what T cells crave

por Delgoffe, Greg M., Powell, Jonathan D.
Publicado 2015

Tumor Microenvironment Metabolism: A New Checkpoint for Anti-Tumor Immunity

por Scharping, Nicole E., Delgoffe, Greg M.
Publicado 2016

STAT heterodimers in immunity: A mixed message or a unique signal?

por Delgoffe, Greg M., Vignali, Dario A.A.
Publicado 2013

Interleukin-35: A Novel Mediator of Peripheral Tolerance

por Delgoffe, Greg M., Vignali, Dario A. A.
Publicado 2013

Fighting in a wasteland: deleterious metabolites and antitumor immunity

por Watson, McLane J., Delgoffe, Greg M.
Publicado 2022

Characteristics of the Tumor Microenvironment That Influence Immune Cell Functions: Hypoxia, Oxidative Stress, Metabolic Alterations

por Augustin, Ryan C., Delgoffe, Greg M., Najjar, Yana G.
Publicado 2020

Metabolic insufficiency underlies intratumoral cytotoxic T cell dysfunction

por Gupta, Tushar, Scharping, Nicole E, Moreci, Rebecca S, Delgoffe, Greg M
Publicado 2015

Tumor-derived alpha-fetoprotein (tAFP) causes immune and metabolic dysfunction in monocyte-derived dendritic cells

por Santos, Patricia M, Pardee, Angela, Delgoffe, Greg M, Butterfield, Lisa H
Publicado 2015

Elucidating the role of Neuropilin-1 in intra-tumoral regulatory T cell stability

por Overacre, Abigail E, Chikina, Maria, Delgoffe, Greg M, Vignali, Dario AA
Publicado 2015

89723 CD105-targeted CAR T cells for the treatment of acute myeloid leukemia

por Lontos, Konstantinos, Wang, Yiyang, Frisch, Andrew, Colbert, Mason, Lohmueller, Jason, Delgoffe, Greg M.
Publicado 2021

Suppressive IL-17A(+)Foxp3(+) and ex-Th17 IL-17A(neg)Foxp3(+) T(reg) cells are a source of tumour-associated T(reg) cells

por Downs-Canner, Stephanie, Berkey, Sara, Delgoffe, Greg M., Edwards, Robert P., Curiel, Tyler, Odunsi, Kunle, Bartlett, David L., Obermajer, Nataša
Publicado 2017

Tumor hypoxia is associated with resistance to PD-1 blockade in squamous cell carcinoma of the head and neck

por Zandberg, Dan P, Menk, Ashley V, Velez, Maria, Normolle, Daniel, DePeaux, Kristin, Liu, Angen, Ferris, Robert L, Delgoffe, Greg M
Publicado 2021

Mesothelin-targeting T cells bearing a novel T cell receptor fusion construct (TRuC) exhibit potent antitumor efficacy against solid tumors

por Ding, Jian, Guyette, Sarah, Schrand, Brett, Geirut, Jessica, Horton, Holly, Guo, Guangwu, Delgoffe, Greg, Menk, Ashley, Baeuerle, Patrick A., Hofmeister, Robert, Tighe, Robert
Publicado 2023

The mammalian Target of Rapamycin (mTOR) regulates T helper cell differentiation through the selective activation of mTORC1 and mTORC2 signaling

por Delgoffe, Greg M., Pollizzi, Kristen N., Waickman, Adam T., Heikamp, Emily, Meyers, David J., Horton, Maureen R., Xiao, Bo, Worley, Paul F., Powell, Jonathan D.
Publicado 2011

4-1BB costimulation induces T cell mitochondrial function and biogenesis enabling cancer immunotherapeutic responses

por Menk, Ashley V., Scharping, Nicole E., Rivadeneira, Dayana B., Calderon, Michael J., Watson, McLane J., Dunstane, Deanna, Watkins, Simon C., Delgoffe, Greg M.
Publicado 2018

mTORC2 Deficiency Alters the Metabolic Profile of Conventional Dendritic Cells

por Watson, Alicia R., Dai, Helong, Zheng, Yawen, Nakano, Ryosuke, Giannou, Anastasios D., Menk, Ashley V., Stolz, Donna B., Delgoffe, Greg M., Thomson, Angus W.
Publicado 2019

Fully murine CD105-targeted CAR-T cells provide an immunocompetent model for CAR-T cell biology

por Lontos, Konstantinos, Wang, Yiyang, Colbert, Mason, Kumar, Alok, Joshi, Supriya, Philbin, Mary, Wang, Yupeng, Frisch, Andrew, Lohmueller, Jason, Rivadeneira, Dayana B., Delgoffe, Greg M.
Publicado 2022

Antiviral epithelial-macrophage crosstalk permits secondary bacterial infections

por Lane, Sidney, White, Tristan L. A., Walsh, Erin E., Cattley, Richard T., Cumberland, Rachel, Hawse, William F., Delgoffe, Greg M., Badylak, Stephen F., Bomberger, Jennifer M.
Publicado 2023

Checkpoint molecules coordinately restrain hyperactivated effector T cells in the tumor microenvironment

por Yang, Min, Du, Wenwen, Yi, Lixian, Wu, Shaoxian, He, Chunyan, Zhai, Wensi, Yue, Cuihua, Sun, Runzi, Menk, Ashley V., Delgoffe, Greg M., Jiang, Jingting, Lu, Binfeng
Publicado 2020

Early TCR Signaling Induces Rapid Aerobic Glycolysis Enabling Distinct Acute T Cell Effector Functions

por Menk, Ashley V., Scharping, Nicole E., Moreci, Rebecca S., Zeng, Xue, Guy, Cliff, Salvatore, Sonia, Bae, Heekyong, Xie, Jianxin, Young, Howard A., Wendell, Stacy Gelhaus, Delgoffe, Greg M.
Publicado 2018