Generalizable design parameters for soluble T cell receptor-based T cell engagers

por Froning, Karen J, Sereno, Arlene, Huang, Flora, Demarest, Stephen J
Publicado 2022

Dichotomous impact of affinity on the function of T cell engaging bispecific antibodies

por Poussin, Mathilde, Sereno, Arlene, Wu, Xiufeng, Huang, Flora, Manro, Jason, Cao, Shanshan, Carpenito, Carmine, Glasebrook, Andrew, Powell Jr, Daniel J, Demarest, Stephen J
Publicado 2021

Comparing domain interactions within antibody Fabs with kappa and lambda light chains

por Toughiri, Raheleh, Wu, Xiufeng, Ruiz, Diana, Huang, Flora, Crissman, John W., Dickey, Mark, Froning, Karen, Conner, Elaine M., Cujec, Thomas P., Demarest, Stephen J.
Publicado 2016

Computational stabilization of T cell receptors allows pairing with antibodies to form bispecifics

por Froning, Karen, Maguire, Jack, Sereno, Arlene, Huang, Flora, Chang, Shawn, Weichert, Kenneth, Frommelt, Anton J., Dong, Jessica, Wu, Xiufeng, Austin, Heather, Conner, Elaine M., Fitchett, Jonathan R., Heng, Aik Roy, Balasubramaniam, Deepa, Hilgers, Mark T., Kuhlman, Brian, Demarest, Stephen J.
Publicado 2020