Why tyrosine kinase inhibitor resistance is common in advanced gastrointestinal stromal tumors

por Tomasetti, Cristian, Demetri, George D, Parmigiani, Giovanni
Publicado 2013

Whole Lung Irradiation in Adults with Metastatic Ewing Sarcoma: Practice Patterns and Implications for Treatment

por Tanguturi, Shyam K., George, Suzanne, Marcus, Karen J., Demetri, George D., Baldini, Elizabeth H.
Publicado 2015

Safety and tolerability of quizartinib, a FLT3 inhibitor, in advanced solid tumors: a phase 1 dose-escalation trial

por Papadopoulos, Kyriakos P., Ben-Ami, Eytan, Patnaik, Amita, Trone, Denise, Li, Jianke, Demetri, George D.
Publicado 2018

Effect of Regorafenib in Delaying Definitive Deterioration in Health-Related Quality of Life in Patients with Advanced Cancer of Three Different Tumor Types

por Hofheinz, Ralf-Dieter, Bruix, Jordi, Demetri, George D, Grothey, Axel, Marian, Marisca, Bartsch, Jennifer, Odom, Dawn
Publicado 2021

Derivation and validation of a risk classification tree for patients with synovial sarcoma

por Neel, Dylan V., Ma, Clement, Collins, Natalie B., Hornick, Jason L., Demetri, George D., Shulman, David S.
Publicado 2022

Real-world survival outcomes in patients with locally advanced or metastatic NTRK fusion-positive solid tumors receiving standard-of-care therapies other than targeted TRK inhibito...

por Hibar, Derrek P., Demetri, George D., Peters, Solange, Davies, Jessica, Humblet, Olivier, Maund, Sophia L., Perez, Laura
Publicado 2022

Effect of gastrointestinal resection on sunitinib exposure in patients with GIST

por de Wit, Djoeke, van Erp, Nielka P, Khosravan, Reza, Wiltshire, Robin, Allred, Randy, Demetri, George D, Guchelaar, Henk-Jan, Gelderblom, Hans
Publicado 2014

Preclinical activity of selinexor, an inhibitor of XPO1, in sarcoma

por Nakayama, Robert, Zhang, Yi-Xiang, Czaplinski, Jeffrey T., Anatone, Alex J., Sicinska, Ewa T., Fletcher, Jonathan A., Demetri, George D., Wagner, Andrew J.
Publicado 2016

The effect of gastrectomy on regorafenib exposure and progression‐free survival in patients with advanced gastrointestinal stromal tumours

por Lubberman, Floor J.E., van der Graaf, Winette T.A., Xu, Lei, Cleton, Adriaan, Demetri, George D., Gelderblom, Hans, van Erp, Nielka P.
Publicado 2019

A retrospective chart review of drug treatment patterns and clinical outcomes among patients with metastatic or recurrent soft tissue sarcoma refractory to one or more prior chemot...

por Wagner, Michael J, Amodu, Leo Ismaila, Duh, Mei Sheng, Korves, Caroline, Solleza, Franco, Manson, Stephanie C, Diaz, José, Neary, Maureen P, Demetri, George D
Publicado 2015

Guillain-Barre syndrome observed with adoptive transfer of lymphocytes genetically engineered with an NY-ESO-1 reactive T-cell receptor

por Joseph, Jocelyn, Nathenson, Michael J., Trinh, Van Anh, Malik, Karan, Nowell, Erica, Carter, Kristen, Weathers, Shiao-Pei, Demetri, George D., Araujo, Dejka, Conley, Anthony P.
Publicado 2019

Effects of Sorafenib on Intra-Tumoral Interstitial Fluid Pressure and Circulating Biomarkers in Patients with Refractory Sarcomas (NCI Protocol 6948)

por Raut, Chandrajit P., Boucher, Yves, Duda, Dan G., Morgan, Jeffrey A., Quek, Richard, Ancukiewicz, Marek, Lahdenranta, Johanna, Eder, J. Paul, Demetri, George D., Jain, Rakesh K.
Publicado 2012

Safety and efficacy of trabectedin when administered in the inpatient versus outpatient setting: Clinical considerations for outpatient administration of trabectedin

por Jones, Robin L., Maki, Robert G., Patel, Shreyaskumar R., Wang, George, McGowan, Tracy A., Shalaby, Waleed S., Knoblauch, Roland E., von Mehren, Margaret, Demetri, George D.
Publicado 2019

Real-World Evidence in Support of Oncology Product Registration: A Systematic Review of New Drug Application and Biologics License Application Approvals from 2015–2020

por Arondekar, Bhakti, Duh, Mei Sheng, Bhak, Rachel H., DerSarkissian, Maral, Huynh, Lynn, Wang, Kelsey, Wojciehowski, John, Wu, Melody, Wornson, Bryon, Niyazov, Alexander, Demetri, George D.
Publicado 2022

Safety and efficacy of Pazopanib in advanced soft tissue sarcoma: PALETTE (EORTC 62072) subgroup analyses

por Cesne, Axel Le, Bauer, Sebastian, Demetri, George D., Han, Guangyang, Dezzani, Luca, Ahmad, Qasim, Blay, Jean-Yves, Judson, Ian, Schöffski, Patrick, Aglietta, Massimo, Hohenberger, Peter, Gelderblom, Hans
Publicado 2019

Response and Mechanisms of Resistance to Larotrectinib and Selitrectinib in Metastatic Undifferentiated Sarcoma Harboring Oncogenic Fusion of NTRK1

por Hemming, Matthew L., Nathenson, Michael J., Lin, Jia-Ren, Mei, Shaolin, Du, Ziming, Malik, Karan, Marino-Enriquez, Adrian, Jagannathan, Jyothi P., Sorger, Peter K., Bertagnolli, Monica, Sicinska, Ewa, Demetri, George D., Santagata, Sandro
Publicado 2020

LRRC15 Targeting in Soft-Tissue Sarcomas: Biological and Clinical Implications

por Ben-Ami, Eytan, Perret, Raul, Huang, Ying, Courgeon, Félicie, Gokhale, Prafulla C., Laroche-Clary, Audrey, Eschle, Benjamin K., Velasco, Valérie, Le Loarer, François, Algeo, Marie-Paule, Purcell, James, Demetri, George D., Italiano, Antoine
Publicado 2020

Phase II study of olaparib in patients with refractory Ewing sarcoma following failure of standard chemotherapy

por Choy, Edwin, Butrynski, James E, Harmon, David C, Morgan, Jeffrey A, George, Suzanne, Wagner, Andrew J, D’Adamo, David, Cote, Gregory M, Flamand, Yael, Benes, Cyril H, Haber, Daniel A, Baselga, Jose M, Demetri, George D
Publicado 2014

Pharmacokinetic–pharmacodynamic guided optimisation of dose and schedule of CGM097, an HDM2 inhibitor, in preclinical and clinical studies

por Bauer, Sebastian, Demetri, George D., Halilovic, Ensar, Dummer, Reinhard, Meille, Christophe, Tan, Daniel S. W., Guerreiro, Nelson, Jullion, Astrid, Ferretti, Stephane, Jeay, Sebastien, Van Bree, Laurence, Hourcade-Potelleret, Florence, Wuerthner, Jens U., Fabre, Claire, Cassier, Philippe A.
Publicado 2021

Cardiac safety of trabectedin monotherapy or in combination with pegylated liposomal doxorubicin in patients with sarcomas and ovarian cancer

por Jones, Robin L., Herzog, Thomas J., Patel, Shreyaskumar R., von Mehren, Margaret, Schuetze, Scott M., Van Tine, Brian A., Coleman, Robert L., Knoblauch, Roland, Triantos, Spyros, Hu, Peter, Shalaby, Waleed, McGowan, Tracy, Monk, Bradley J., Demetri, George D.
Publicado 2021