Apolipoprotein E moderates the association between Non-APOE Polygenic Risk Score for Alzheimer’s Disease and Aging on Preclinical Cognitive Function

por Xu, Yuexuan, Sun, Zhongxuan, Jonaitis, Erin, Deming, Yuetiva, Lu, Qiongshi, Johnson, Sterling C., Engelman, Corinne D.
Publicado 2023

Genome-wide association study for variants that modulate relationships between cerebrospinal fluid amyloid-beta 42, tau, and p-tau levels

por Maxwell, Taylor J., Corcoran, Chris, del-Aguila, Jorge L., Budde, John P., Deming, Yuetiva, Cruchaga, Carlos, Goate, Alison M., Kauwe, John S. K.
Publicado 2018

Role of ABCA7 loss-of-function variant in Alzheimer's disease: a replication study in European–Americans

por Del-Aguila, Jorge L., Fernández, Maria Victoria, Jimenez, Jessica, Black, Kathleen, Ma, Shengmei, Deming, Yuetiva, Carrell, David, Saef, Ben, Howells, Bill, Budde, John, Cruchaga, Carlos
Publicado 2015

Identification of plexin A4 as a novel clusterin receptor links two Alzheimer’s disease risk genes

por Kang, Silvia S., Kurti, Aishe, Wojtas, Aleksandra, Baker, Kelsey E., Liu, Chia-Chen, Kanekiyo, Takahisa, Deming, Yuetiva, Cruchaga, Carlos, Estus, Steven, Bu, Guojun, Fryer, John D.
Publicado 2016

Evaluation of Gene-Based Family-Based Methods to Detect Novel Genes Associated With Familial Late Onset Alzheimer Disease

por Fernández, Maria V., Budde, John, Del-Aguila, Jorge L., Ibañez, Laura, Deming, Yuetiva, Harari, Oscar, Norton, Joanne, Morris, John C., Goate, Alison M., Cruchaga, Carlos
Publicado 2018

CSF metabolites associate with CSF tau and improve prediction of Alzheimer's disease status

por Dong, Ruocheng, Darst, Burcu F., Deming, Yuetiva, Ma, Yue, Lu, Qiongshi, Zetterberg, Henrik, Blennow, Kaj, Carlsson, Cynthia M., Johnson, Sterling C., Asthana, Sanjay, Engelman, Corinne D.
Publicado 2021

Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations

por Panyard, Daniel J., Kim, Kyeong Mo, Darst, Burcu F., Deming, Yuetiva K., Zhong, Xiaoyuan, Wu, Yuchang, Kang, Hyunseung, Carlsson, Cynthia M., Johnson, Sterling C., Asthana, Sanjay, Engelman, Corinne D., Lu, Qiongshi
Publicado 2021

Exploring common genetic contributors to neuroprotection from amyloid pathology

por Seto, Mabel, Mahoney, Emily R., Dumitrescu, Logan, Ramanan, Vijay K., Engelman, Corinne D., Deming, Yuetiva, Albert, Marilyn, Johnson, Sterling C., Zetterberg, Henrik, Blennow, Kaj, Vemuri, Prashanthi, Jefferson, Angela L., Hohman, Timothy J.
Publicado 2022

CSF metabolites associated with biomarkers of Alzheimer’s disease pathology

por Dong, Ruocheng, Lu, Qiongshi, Kang, Hyunseung, Suridjan, Ivonne, Kollmorgen, Gwendlyn, Wild, Norbert, Deming, Yuetiva, Van Hulle, Carol A., Anderson, Rozalyn M., Zetterberg, Henrik, Blennow, Kaj, Carlsson, Cynthia M., Asthana, Sanjay, Johnson, Sterling C., Engelman, Corinne D.
Publicado 2023

Analysis of neurodegenerative Mendelian genes in clinically diagnosed Alzheimer Disease

por Fernández, Maria Victoria, Kim, Jong Hun, Budde, John P., Black, Kathleen, Medvedeva, Alexandra, Saef, Ben, Deming, Yuetiva, Del-Aguila, Jorge, Ibañez, Laura, Dube, Umber, Harari, Oscar, Norton, Joanne, Chasse, Rachel, Morris, John C., Goate, Alison, Cruchaga, Carlos
Publicado 2017

Higher CSF sTREM2 and microglia activation are associated with slower rates of beta‐amyloid accumulation

por Ewers, Michael, Biechele, Gloria, Suárez‐Calvet, Marc, Sacher, Christian, Blume, Tanja, Morenas‐Rodriguez, Estrella, Deming, Yuetiva, Piccio, Laura, Cruchaga, Carlos, Kleinberger, Gernot, Shaw, Leslie, Trojanowski, John Q, Herms, Jochen, Dichgans, Martin, Brendel, Matthias, Haass, Christian, Franzmeier, Nicolai
Publicado 2020

Effect of Pathway-specific Polygenic Risk Scores for Alzheimer’s Disease (AD) on Rate of Change in Cognitive Function and AD-related Biomarkers among Asymptomatic Individuals

por Xu, Yuexuan, Vasiljevic, Eva, Deming, Yuetiva K., Jonaitis, Erin M., Koscik, Rebecca L., Van Hulle, Carol A., Lu, Qiongshi, Carboni, Margherita, Kollmorgen, Gwendlyn, Wild, Norbert, Carlsson, Cynthia M., Johnson, Sterling C., Zetterberg, Henrik, Blennow, Kaj, Engelman, Corinne D.
Publicado 2023

Early increase of CSF sTREM2 in Alzheimer’s disease is associated with tau related-neurodegeneration but not with amyloid-β pathology

por Suárez-Calvet, Marc, Morenas-Rodríguez, Estrella, Kleinberger, Gernot, Schlepckow, Kai, Caballero, Miguel Ángel Araque, Franzmeier, Nicolai, Capell, Anja, Fellerer, Katrin, Nuscher, Brigitte, Eren, Erden, Levin, Johannes, Deming, Yuetiva, Piccio, Laura, Karch, Celeste M., Cruchaga, Carlos, Shaw, Leslie M., Trojanowski, John Q., Weiner, Michael, Ewers, Michael, Haass, Christian
Publicado 2019

Unique genetic architecture of CSF and brain metabolites pinpoints the novel targets for the traits of human wellness

por Wang, Ciyang, Western, Dan, Yang, Chengran, Ali, Muhammad, Wang, Lihua, Gorijala, Priyanka, Timsina, Jigyasha, Ruiz, Agustín, Pastor, Pau, Fernandez, Maria, Panyard, Daniel, Engelman, Corinne, Deming, Yuetiva, Boada, Merce, Cano, Amanda, García-González, Pablo, Graff-Radford, Neill, Mori, Hiroshi, Lee, Jae-Hong, Perrin, Richard, Sung, Yun Ju, Cruchaga, Carlos
Publicado 2023

Chitinase-3-like 1 protein (CHI3L1) locus influences cerebrospinal fluid levels of YKL-40

por Deming, Yuetiva, Black, Kathleen, Carrell, David, Cai, Yefei, Del-Aguila, Jorge L., Fernandez, Maria Victoria, Budde, John, Ma, ShengMei, Saef, Benjamin, Howells, Bill, Bertelsen, Sarah, Huang, Kuan-lin, Sutphen, Courtney L., Tarawneh, Rawan, Fagan, Anne M., Holtzman, David M., Morris, John C., Goate, Alison M., Dougherty, Joseph D., Cruchaga, Carlos
Publicado 2016

African Americans Have Differences in CSF Soluble TREM2 and Associated Genetic Variants

por Schindler, Suzanne E., Cruchaga, Carlos, Joseph, Amulya, McCue, Lena, Farias, Fabiana H.G., Wilkins, Consuelo H., Deming, Yuetiva, Henson, Rachel L., Mikesell, Robert J., Piccio, Laura, Llibre-Guerra, Jorge J., Moulder, Krista L., Fagan, Anne M., Ances, Beau M., Benzinger, Tammie L.S., Xiong, Chengjie, Holtzman, David M., Morris, John C.
Publicado 2021

Gut inflammation associated with age and Alzheimer’s disease pathology: a human cohort study

por Heston, Margo B., Hanslik, Kendra L., Zarbock, Katie R., Harding, Sandra J., Davenport-Sis, Nancy J., Kerby, Robert L., Chin, Nathaniel, Sun, Yi, Hoeft, Ana, Deming, Yuetiva, Vogt, Nicholas M., Betthauser, Tobey J., Johnson, Sterling C., Asthana, Sanjay, Kollmorgen, Gwendlyn, Suridjan, Ivonne, Wild, Norbert, Zetterberg, Henrik, Blennow, Kaj, Rey, Federico E., Bendlin, Barbara B., Ulland, Tyler K.
Publicado 2023

Genetic studies of plasma analytes identify novel potential biomarkers for several complex traits

por Deming, Yuetiva, Xia, Jian, Cai, Yefei, Lord, Jenny, Del-Aguila, Jorge L., Fernandez, Maria Victoria, Carrell, David, Black, Kathleen, Budde, John, Ma, ShengMei, Saef, Benjamin, Howells, Bill, Bertelsen, Sarah, Bailey, Matthew, Ridge, Perry G., Holtzman, David, Morris, John C., Bales, Kelly, Pickering, Eve H., Lee, Jin-Moo, Heitsch, Laura, Kauwe, John, Goate, Alison, Piccio, Laura, Cruchaga, Carlos
Publicado 2016

CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline

por Suárez‐Calvet, Marc, Capell, Anja, Araque Caballero, Miguel Ángel, Morenas‐Rodríguez, Estrella, Fellerer, Katrin, Franzmeier, Nicolai, Kleinberger, Gernot, Eren, Erden, Deming, Yuetiva, Piccio, Laura, Karch, Celeste M, Cruchaga, Carlos, Paumier, Katrina, Bateman, Randall J, Fagan, Anne M, Morris, John C, Levin, Johannes, Danek, Adrian, Jucker, Mathias, Masters, Colin L, Rossor, Martin N, Ringman, John M, Shaw, Leslie M, Trojanowski, John Q, Weiner, Michael, Ewers, Michael, Haass, Christian
Publicado 2018