Non-coding RNAs and ferroptosis: potential implications for cancer therapy

por Balihodzic, Amar, Prinz, Felix, Dengler, Michael A., Calin, George A., Jost, Philipp J., Pichler, Martin
Publicado 2022

p53 Hypersensitivity Is the Predominant Mechanism of the Unique Responsiveness of Testicular Germ Cell Tumor (TGCT) Cells to Cisplatin

por Gutekunst, Matthias, Oren, Moshe, Weilbacher, Andrea, Dengler, Michael A., Markwardt, Christiane, Thomale, Jürgen, Aulitzky, Walter E., van der Kuip, Heiko
Publicado 2011

Robust autoactivation for apoptosis by BAK but not BAX highlights BAK as an important therapeutic target

por Iyer, Sweta, Uren, Rachel T., Dengler, Michael A., Shi, Melissa X., Uno, Etsuko, Adams, Jerry M., Dewson, Grant, Kluck, Ruth M.
Publicado 2020

Oncogenic Stress Induced by Acute Hyper-Activation of Bcr-Abl Leads to Cell Death upon Induction of Excessive Aerobic Glycolysis

por Dengler, Michael A., Staiger, Annette M., Gutekunst, Matthias, Hofmann, Ute, Doszczak, Malgorzata, Scheurich, Peter, Schwab, Matthias, Aulitzky, Walter E., van der Kuip, Heiko
Publicado 2011

The BCL-2 family member BOK promotes KRAS-driven lung cancer progression in a p53-dependent manner

por Meinhardt, Anna-Lena, Munkhbaatar, Enkhtsetseg, Höckendorf, Ulrike, Dietzen, Michelle, Dechant, Marta, Anton, Martina, Jacob, Anne, Steiger, Katja, Weichert, Wilko, Brcic, Luka, McGranahan, Nicholas, Branca, Caterina, Kaufmann, Thomas, Dengler, Michael A., Jost, Philipp J.
Publicado 2022

Acquired mutations in BAX confer resistance to BH3-mimetic therapy in acute myeloid leukemia

por Moujalled, Donia M., Brown, Fiona C., Chua, Chong Chyn, Dengler, Michael A., Pomilio, Giovanna, Anstee, Natasha S., Litalien, Veronique, Thompson, Ella, Morley, Thomas, MacRaild, Sarah, Tiong, Ing S., Morris, Rhiannon, Dun, Karen, Zordan, Adrian, Shah, Jaynish, Banquet, Sebastien, Halilovic, Ensar, Morris, Erick, Herold, Marco J., Lessene, Guillaume, Adams, Jerry M., Huang, David C. S., Roberts, Andrew W., Blombery, Piers, Wei, Andrew H.
Publicado 2023

Flexible Usage and Interconnectivity of Diverse Cell Death Pathways Protect against Intracellular Infection

por Doerflinger, Marcel, Deng, Yexuan, Whitney, Paul, Salvamoser, Ranja, Engel, Sven, Kueh, Andrew J., Tai, Lin, Bachem, Annabell, Gressier, Elise, Geoghegan, Niall D., Wilcox, Stephen, Rogers, Kelly L., Garnham, Alexandra L., Dengler, Michael A., Bader, Stefanie M., Ebert, Gregor, Pearson, Jaclyn S., De Nardo, Dominic, Wang, Nancy, Yang, Chenying, Pereira, Milton, Bryant, Clare E., Strugnell, Richard A., Vince, James E., Pellegrini, Marc, Strasser, Andreas, Bedoui, Sammy, Herold, Marco J.
Publicado 2020

Nanobody cocktails potently neutralize SARS-CoV-2 D614G N501Y variant and protect mice

por Pymm, Phillip, Adair, Amy, Chan, Li-Jin, Cooney, James P., Mordant, Francesca L., Allison, Cody C., Lopez, Ester, Haycroft, Ebene R., O’Neill, Matthew T., Tan, Li Lynn, Dietrich, Melanie H., Drew, Damien, Doerflinger, Marcel, Dengler, Michael A., Scott, Nichollas E., Wheatley, Adam K., Gherardin, Nicholas A., Venugopal, Hariprasad, Cromer, Deborah, Davenport, Miles P., Pickering, Raelene, Godfrey, Dale I., Purcell, Damian F. J., Kent, Stephen J., Chung, Amy W., Subbarao, Kanta, Pellegrini, Marc, Glukhova, Alisa, Tham, Wai-Hong
Publicado 2021