Engineering Enzymatically Activated “Molecular Grenades” for Cancer

por Denmeade, Samuel R., Isaacs, John T.
Publicado 2012

Fatty Acid Synthesis in Prostate Cancer: Vulnerability or Epiphenomenon?

por Sena, Laura A., Denmeade, Samuel R.
Publicado 2021

Quantification of Mesenchymal Stem Cells (MSCs) at Sites of Human Prostate Cancer

por Brennen, W. Nathaniel, Chen, Shuangling, Denmeade, Samuel R., Isaacs, John T.
Publicado 2012

The Influence of Prednisone on the Efficacy of Docetaxel in Men with Metastatic Castration-Resistant Prostate Cancer

por Teply, Benjamin A., Luber, Brandon, Denmeade, Samuel R., Antonarakis, Emmanuel S.
Publicado 2015

Albumin-linked prostate-specific antigen-activated thapsigargin- and niclosamide-based molecular grenades targeting the microenvironment in metastatic castration-resistant prostate...

por Akinboye, Emmanuel S., Brennen, W. Nathaniel, Denmeade, Samuel R., Isaacs, John T.
Publicado 2019

Mipsagargin: The Beginning—Not the End—of Thapsigargin Prodrug-Based Cancer Therapeutics

por Isaacs, John T., Brennen, William Nathaniel, Christensen, Søren Brøgger, Denmeade, Samuel R.
Publicado 2021

Bipolar Androgen Therapy Followed by Androgen Receptor Inhibition as Sequential Therapy for Prostate Cancer

por Denmeade, Samuel R, Sena, Laura A, Wang, Hao, Antonarakis, Emmanuel S, Markowski, Mark C
Publicado 2023

PSA-selective activation of cytotoxic human serine proteases within the tumor microenvironment as a therapeutic strategy to target prostate cancer

por Rogers, Oliver C., Anthony, Lizamma, Rosen, D. Marc, Brennen, W. Nathaniel, Denmeade, Samuel R.
Publicado 2018

CCAAT/Enhancer Binding Protein β Controls Androgen Deprivation-Induced Senescence in Prostate Cancer Cells

por Barakat, David J., Zhang, Jing, Barberi, Theresa, Denmeade, Samuel R., Friedman, Alan D., Paz-Priel, Ido
Publicado 2015

Concise Review: Mesenchymal Stem Cell‐Based Drug Delivery: The Good, the Bad, the Ugly, and the Promise

por Krueger, Timothy E. G., Thorek, Daniel L. J., Denmeade, Samuel R., Isaacs, John T., Brennen, W. Nathaniel
Publicado 2018

Clinical Efficacy of Bipolar Androgen Therapy in Men with Metastatic Castration-Resistant Prostate Cancer and Combined Tumor-Suppressor Loss

por Markowski, Mark C., Wang, Hao, De Marzo, Angelo M., Schweizer, Michael T., Antonarakis, Emmanuel S., Denmeade, Samuel R.
Publicado 2022

Reversing the effects of androgen-deprivation therapy in men with metastatic castration-resistant prostate cancer

por Marshall, Catherine H., Tunacao, Jessa, Danda, Varun, Tsai, Hua-Ling, Barber, John, Gawande, Rakhee, Weiss, Clifford R., Denmeade, Samuel R., Joshu, Corinne
Publicado 2021

The N-Myc Down Regulated Gene1 (NDRG1) Is a Rab4a Effector Involved in Vesicular Recycling of E-Cadherin

por Kachhap, Sushant K., Faith, Dennis, Qian, David Z., Shabbeer, Shabana, Galloway, Nathan L., Pili, Roberto, Denmeade, Samuel R., DeMarzo, Angelo M., Carducci, Michael A.
Publicado 2007

Targeted delivery of cytotoxic proteins to prostate cancer via conjugation to small molecule urea-based PSMA inhibitors

por Rogers, O. C., Rosen, D. M., Antony, L., Harper, H. M., Das, D., Yang, X., Minn, I., Mease, R. C., Pomper, M. G., Denmeade, S. R.
Publicado 2021

Mesenchymal stem cell infiltration during neoplastic transformation of the human prostate

por Brennen, W. Nathaniel, Zhang, Baohui, Kulac, Ibrahim, Kisteman, L. Nelleke, Antony, Lizamma, Wang, Hao, Meeker, Alan K., De Marzo, Angelo M., Garraway, Isla P., Denmeade, Samuel R., Isaacs, John T.
Publicado 2017

A Phase I Study to Assess the Safety and Cancer‐Homing Ability of Allogeneic Bone Marrow‐Derived Mesenchymal Stem Cells in Men with Localized Prostate Cancer

por Schweizer, Michael T., Wang, Hao, Bivalacqua, Trinity J., Partin, Alan W., Lim, Su Jin, Chapman, Carolyn, Abdallah, Rehab, Levy, Oren, Bhowmick, Neil A., Karp, Jeffrey M., De Marzo, Angelo, Isaacs, John T., Brennen, W. Nathaniel, Denmeade, Samuel R.
Publicado 2019

In Reply

por Brennen, W. Nathaniel, Schweizer, Michael T., Wang, Hao, Bivalacqua, Trinity J., Partin, Alan W., Lim, Su Jin, Chapman, Carolyn, Abdallah, Rehab, Levy, Oren, Bhowmick, Neil A., Karp, Jeffrey M., De Marzo, Angelo, Isaacs, John T., Denmeade, Samuel R.
Publicado 2019

Role of androgen receptor splice variant 7 (AR-V7) in prostate cancer resistance to 2(nd) generation androgen receptor signaling inhibitors

por Zhu, Yezi, Dalrymple, Susan L., Coleman, Ilsa, Zheng, S. Lilly, Xu, Jianfeng, Hooper, Jody E., Antonarakis, Emmanuel S., De Marzo, Angelo M., Meeker, Alan K., Nelson, Peter S., Isaacs, William B., Denmeade, Samuel R., Luo, Jun, Brennen, W. Nathaniel, Isaacs, John T.
Publicado 2020

MYC-driven increases in mitochondrial DNA copy number occur early and persist throughout prostatic cancer progression

por Chen, Jiayu, Zheng, Qizhi, Hicks, Jessica L., Trabzonlu, Levent, Ozbek, Busra, Jones, Tracy, Vaghasia, Ajay, Larman, Tatianna C., Wang, Rulin, Markowski, Mark C., Denmeade, Sam R., Pienta, Kenneth J., Hruban, Ralph H., Antonarakis, Emmanuel S., Gupta, Anuj, Dang, Chi V, Yegnasubramanian, Srinivasan, De Marzo, Angelo M.
Publicado 2023

Detection fidelity of AR mutations in plasma derived cell-free DNA

por Goldstein, Alexa, Toro, Patricia Valda, Lee, Justin, Silberstein, John L., Nakazawa, Mary, Waters, Ian, Cravero, Karen, Chu, David, Cochran, Rory L., Kim, Minsoo, Shinn, Daniel, Torquato, Samantha, Hughes, Robert M., Pallavajjala, Aparna, Carducci, Michael A., Paller, Channing J., Denmeade, Samuel R., Kressel, Bruce, Trock, Bruce J., Eisenberger, Mario A., Antonarakis, Emmanuel S., Park, Ben H., Hurley, Paula J.
Publicado 2017