Allosteric regulation by membranes and hydrophobic subsites in phospholipase A(2) enzymes determine their substrate specificity

por Dennis, Edward A.
Publicado 2022

Outtakes from My Journey through the World of LIPID MAPS

por Dennis, Edward A.
Publicado 2022

Membrane Association Allosterically Regulates Phospholipase A(2) Enzymes and Their Specificity

por Mouchlis, Varnavas D., Dennis, Edward A.
Publicado 2022

Lipidomics Reveals Dramatic Physiological Kinetic Isotope Effects during the Enzymatic Oxygenation of Polyunsaturated Fatty Acids Ex Vivo

por Navratil, Aaron R., Shchepinov, Mikhail S., Dennis, Edward A.
Publicado 2017

Substrate-Specific Inhibition Constants for Phospholipase A(2) Acting on Unique Phospholipid Substrates in Mixed Micelles and Membranes Using Lipidomics

por Mouchlis, Varnavas D., Armando, Aaron, Dennis, Edward A.
Publicado 2019

Efficacy of dietary odd-chain saturated fatty acid pentadecanoic acid parallels broad associated health benefits in humans: could it be essential?

por Venn-Watson, Stephanie, Lumpkin, Richard, Dennis, Edward A.
Publicado 2020

Omega-3 versus Omega-6 fatty acid availability is controlled by hydrophobic site geometries of phospholipase A(2)s

por Hayashi, Daiki, Mouchlis, Varnavas D., Dennis, Edward A.
Publicado 2021

Assessing Phospholipase A(2) Activity toward Cardiolipin by Mass Spectrometry

por Hsu, Yuan-Hao, Dumlao, Darren S., Cao, Jian, Dennis, Edward A.
Publicado 2013

Correction: Assessing Phospholipase A(2) Activity toward Cardiolipin by Mass Spectrometry

por Hsu, Yuan-Hao, Dumlao, Darren S., Cao, Jian, Dennis, Edward A.
Publicado 2013

How Managed Care May Choose Hospitals for Contracts for Laparoscopic Cholecystectomy

por Weiland, Dennis Edward, Caruso, Daniel Martin, Wesche, Daniel Eric, Bay, Ralph Curtis
Publicado 1997

Membrane Allostery and Unique Hydrophobic Sites Promote Enzyme Substrate Specificity

por Mouchlis, Varnavas D., Chen, Yuan, McCammon, J. Andrew, Dennis, Edward A.
Publicado 2018

Using Delta/DRG Diagrams and Decision Tree Analysis to Select a Cost-Effective Surgery for Cholecystitis

por Weiland, Dennis Edward, Caruso, Daniel Martin, Kassir, Andrew, Bay, Ralph Curtis, Malone, James M.
Publicado 1997

Insertion of the Ca(2+)-Independent Phospholipase A(2) into a Phospholipid Bilayer via Coarse-Grained and Atomistic Molecular Dynamics Simulations

por Bucher, Denis, Hsu, Yuan-Hao, Mouchlis, Varnavas D., Dennis, Edward A., McCammon, J. Andrew
Publicado 2013

Highly Potent 2-Oxoester Inhibitors of Cytosolic Phospholipase A(2) (GIVA cPLA(2))

por Psarra, Anastasia, Kokotou, Maroula G., Galiatsatou, Gerasimia, Mouchlis, Varnavas D., Dennis, Edward A., Kokotos, George
Publicado 2018

Correction to “Highly Potent 2-Oxoester Inhibitors of Cytosolic Phospholipase A(2) (GIVA cPLA(2))”

por Psarra, Anastasia, Kokotou, Maroula G., Galiatsatou, Gerasimia, Mouchlis, Varnavas D., Dennis, Edward A., Kokotos, George
Publicado 2019

2-Oxoester Phospholipase A(2) Inhibitors with Enhanced Metabolic Stability

por Koutoulogenis, Giorgos S., Kokotou, Maroula G., Hayashi, Daiki, Mouchlis, Varnavas D., Dennis, Edward A., Kokotos, George
Publicado 2020

Automated Annotation of Sphingolipids Including Accurate Identification of Hydroxylation Sites Using MS(n) Data

por Hartler, Jürgen, Armando, Aaron M., Trötzmüller, Martin, Dennis, Edward A., Köfeler, Harald C., Quehenberger, Oswald
Publicado 2020

Pharmacological correction of a defect in PPARγ signaling ameliorates disease severity in Cftr-deficient mice

por Harmon, Gregory S., Dumlao, Darren S., Ng, Damian T., Barrett, Kim E., Dennis, Edward A., Dong, Hui, Glass, Christopher K.
Publicado 2010

Lipoprotein-associated phospholipase A(2): A paradigm for allosteric regulation by membranes

por Mouchlis, Varnavas D., Hayashi, Daiki, Vasquez, Alexis M., Cao, Jian, McCammon, J. Andrew, Dennis, Edward A.
Publicado 2022

Fluoroketone Inhibition of Ca(2+)-Independent Phospholipase A(2) through Binding Pocket Association Defined by Hydrogen/Deuterium Exchange and Molecular Dynamics

por Hsu, Yuan-Hao, Bucher, Denis, Cao, Jian, Li, Sheng, Yang, Sheng-Wei, Kokotos, George, Woods, Virgil L., McCammon, J. Andrew, Dennis, Edward A.
Publicado 2012