Precision Medicine in Type 2 Diabetes: Using Individualized Prediction Models to Optimize Selection of Treatment

por Dennis, John M.
Publicado 2020

Improving Survival of Critical Care Patients With Coronavirus Disease 2019 in England: A National Cohort Study, March to June 2020*

por Dennis, John M., McGovern, Andrew P., Vollmer, Sebastian J., Mateen, Bilal A.
Publicado 2020

Disease progression and treatment response in data-driven subgroups of type 2 diabetes compared with models based on simple clinical features: an analysis using clinical trial data

por Dennis, John M, Shields, Beverley M, Henley, William E, Jones, Angus G, Hattersley, Andrew T
Publicado 2019

A national retrospective study of the association between serious operational problems and COVID-19 specific intensive care mortality risk

por Wilde, Harrison, Dennis, John M., McGovern, Andrew P., Vollmer, Sebastian J., Mateen, Bilal A.
Publicado 2021

Evaluating associations between the benefits and risks of drug therapy in type 2 diabetes: a joint modeling approach

por Dennis, John M, Shields, Beverley M, Jones, Angus G, Pearson, Ewan R, Hattersley, Andrew T, Henley, William E
Publicado 2018

Recent UK type 2 diabetes treatment guidance represents a near whole population indication for SGLT2-inhibitor therapy

por Young, Katherine G., Hopkins, Rhian, Shields, Beverley M., Thomas, Nicholas J., McGovern, Andrew P., Dennis, John M.
Publicado 2023

What to do with diabetes therapies when HbA1c lowering is inadequate: add, switch, or continue? A MASTERMIND study

por McGovern, Andrew P., Dennis, John M., Shields, Beverley M., Hattersley, Andrew T., Pearson, Ewan R., Jones, Angus G.
Publicado 2019

Prior event rate ratio adjustment produced estimates consistent with randomized trial: a diabetes case study

por Rodgers, Lauren R., Dennis, John M., Shields, Beverley M., Mounce, Luke, Fisher, Ian, Hattersley, Andrew T., Henley, William E.
Publicado 2020

The disproportionate excess mortality risk of COVID-19 in younger people with diabetes warrants vaccination prioritisation

por McGovern, Andrew P., Thomas, Nick J., Vollmer, Sebastian J., Hattersley, Andrew T., Mateen, Bilal A., Dennis, John M.
Publicado 2021

Trends in 28-Day Mortality of Critical Care Patients With Coronavirus Disease 2019 in the United Kingdom: A National Cohort Study, March 2020 to January 2021*

por Dennis, John M., McGovern, Andrew P., Thomas, Nicholas J., Wilde, Harrison, Vollmer, Sebastian J., Mateen, Bilal A.
Publicado 2021

Comparison of causal forest and regression-based approaches to evaluate treatment effect heterogeneity: an application for type 2 diabetes precision medicine

por Venkatasubramaniam, Ashwini, Mateen, Bilal A., Shields, Beverley M., Hattersley, Andrew T., Jones, Angus G., Vollmer, Sebastian J., Dennis, John M.
Publicado 2023

Risk of Anemia With Metformin Use in Type 2 Diabetes: A MASTERMIND Study

por Donnelly, Louise A., Dennis, John M., Coleman, Ruth L., Sattar, Naveed, Hattersley, Andrew T., Holman, Rury R., Pearson, Ewan R.
Publicado 2020

Time trends and geographical variation in prescribing of drugs for diabetes in England from 1998 to 2017

por Curtis, Helen J., Dennis, John M., Shields, Beverley M., Walker, Alex J., Bacon, Seb, Hattersley, Andrew T., Jones, Angus G., Goldacre, Ben
Publicado 2018

Logistic regression has similar performance to optimised machine learning algorithms in a clinical setting: application to the discrimination between type 1 and type 2 diabetes in...

por Lynam, Anita L., Dennis, John M., Owen, Katharine R., Oram, Richard A., Jones, Angus G., Shields, Beverley M., Ferrat, Lauric A.
Publicado 2020

Hospital bed capacity and usage across secondary healthcare providers in England during the first wave of the COVID-19 pandemic: a descriptive analysis

por Mateen, Bilal Akhter, Wilde, Harrison, Dennis, John M, Duncan, Andrew, Thomas, Nick, McGovern, Andrew, Denaxas, Spiros, Keeling, Matt, Vollmer, Sebastian
Publicado 2021

Correction to: The impact of population-level HbA(1c) screening on reducing diabetes diagnostic delay in middle-aged adults: a UK Biobank analysis

por Young, Katherine G., McGovern, Andrew P., Barroso, Inês, Hattersley, Andrew T., Jones, Angus G., Shields, Beverley M., Thomas, Nicholas J., Dennis, John M.
Publicado 2023

The impact of population-level HbA(1c) screening on reducing diabetes diagnostic delay in middle-aged adults: a UK Biobank analysis

por Young, Katherine G., McGovern, Andrew P., Barroso, Inês, Hattersley, Andrew T., Jones, Angus G., Shields, Beverley M., Thomas, Nicholas J., Dennis, John M.
Publicado 2022

Type 2 Diabetes and COVID-19–Related Mortality in the Critical Care Setting: A National Cohort Study in England, March–July 2020

por Dennis, John M., Mateen, Bilal A., Sonabend, Raphael, Thomas, Nicholas J., Patel, Kashyap A., Hattersley, Andrew T., Denaxas, Spiros, McGovern, Andrew P., Vollmer, Sebastian J.
Publicado 2021

The association between mechanical ventilator compatible bed occupancy and mortality risk in intensive care patients with COVID-19: a national retrospective cohort study

por Wilde, Harrison, Mellan, Thomas, Hawryluk, Iwona, Dennis, John M., Denaxas, Spiros, Pagel, Christina, Duncan, Andrew, Bhatt, Samir, Flaxman, Seth, Mateen, Bilal A., Vollmer, Sebastian J.
Publicado 2021

Risk factors for genital infections in people initiating SGLT2 inhibitors and their impact on discontinuation

por McGovern, Andrew P, Hogg, Michael, Shields, Beverley M, Sattar, Naveed A, Holman, Rury R, Pearson, Ewan R, Hattersley, Andrew T, Jones, Angus G, Dennis, John M
Publicado 2020