c-MYC-Driven Polyamine Metabolism in Ovarian Cancer: From Pathogenesis to Early Detection and Therapy

por Chen, Yihui, León-Letelier, Ricardo A., Abdel Sater, Ali Hussein, Vykoukal, Jody, Dennison, Jennifer B., Hanash, Samir, Fahrmann, Johannes F.
Publicado 2023

Abortive Autophagy Induces Endoplasmic Reticulum Stress and Cell Death in Cancer Cells

por Claerhout, Sofie, Dutta, Bhaskar, Bossuyt, Wouter, Zhang, Fan, Nguyen-Charles, Catherine, Dennison, Jennifer B., Yu, Qinghua, Yu, Shuangxing, Balázsi, Gábor, Lu, Yiling, Mills, Gordon B.
Publicado 2012

The beneficial effects of a gas-permeable flask for expansion of Tumor-Infiltrating lymphocytes as reflected in their mitochondrial function and respiration capacity

por Forget, Marie-Andrée, Haymaker, Cara, Dennison, Jennifer B, Toth, Christopher, Maiti, Sourindra, Fulbright, Orenthial J, Cooper, Laurence J N, Hwu, Patrick, Radvanyi, Laszlo G, Bernatchez, Chantale
Publicado 2015

Deep Learning Models for Automated Assessment of Breast Density Using Multiple Mammographic Image Types

por Rigaud, Bastien, Weaver, Olena O., Dennison, Jennifer B., Awais, Muhammad, Anderson, Brian M., Chiang, Ting-Yu D., Yang, Wei T., Leung, Jessica W. T., Hanash, Samir M., Brock, Kristy K.
Publicado 2022

Kynureninase Upregulation Is a Prominent Feature of NFR2-Activated Cancers and Is Associated with Tumor Immunosuppression and Poor Prognosis

por León-Letelier, Ricardo A., Abdel Sater, Ali H., Chen, Yihui, Park, Soyoung, Wu, Ranran, Irajizad, Ehsan, Dennison, Jennifer B., Katayama, Hiroyuki, Vykoukal, Jody V., Hanash, Samir, Ostrin, Edwin J., Fahrmann, Johannes F.
Publicado 2023

A MYC-Driven Plasma Polyamine Signature for Early Detection of Ovarian Cancer

por Fahrmann, Johannes F., Irajizad, Ehsan, Kobayashi, Makoto, Vykoukal, Jody, Dennison, Jennifer B., Murage, Eunice, Wu, Ranran, Long, James P., Do, Kim-Anh, Celestino, Joseph, Lu, Karen H., Lu, Zhen, Bast, Robert C., Hanash, Samir
Publicado 2021

Contributions of Circulating microRNAs for Early Detection of Lung Cancer

por Vykoukal, Jody, Fahrmann, Johannes F., Patel, Nikul, Shimizu, Masayoshi, Ostrin, Edwin J., Dennison, Jennifer B., Ivan, Cristina, Goodman, Gary E., Thornquist, Mark D., Barnett, Matt J., Feng, Ziding, Calin, George A., Hanash, Samir M.
Publicado 2022

Novel UHRF1-MYC Axis in Acute Lymphoblastic Leukemia

por Park, Soyoung, Sater, Ali H. Abdel, Fahrmann, Johannes F., Irajizad, Ehsan, Cai, Yining, Katayama, Hiroyuki, Vykoukal, Jody, Kobayashi, Makoto, Dennison, Jennifer B., Garcia-Manero, Guillermo, Mullighan, Charles G., Gu, Zhaohui, Konopleva, Marina, Hanash, Samir
Publicado 2022

Plasma Based Protein Signatures Associated with Small Cell Lung Cancer

por Fahrmann, Johannes F., Katayama, Hiroyuki, Irajizad, Ehsan, Chakraborty, Ashish, Kato, Taketo, Mao, Xiangying, Park, Soyoung, Murage, Eunice, Rusling, Leona, Yu, Chuan-Yih, Cai, Yinging, Hsiao, Fu Chung, Dennison, Jennifer B., Tran, Hai, Ostrin, Edwin, Wilson, David O., Yuan, Jian-Min, Vykoukal, Jody, Hanash, Samir
Publicado 2021

Caveolin-1-mediated sphingolipid oncometabolism underlies a metabolic vulnerability of prostate cancer

por Vykoukal, Jody, Fahrmann, Johannes F., Gregg, Justin R., Tang, Zhe, Basourakos, Spyridon, Irajizad, Ehsan, Park, Sanghee, Yang, Guang, Creighton, Chad J., Fleury, Alia, Mayo, Jeffrey, Paulucci-Holthauzen, Adriana, Dennison, Jennifer B., Murage, Eunice, Peterson, Christine B., Davis, John W., Kim, Jeri, Hanash, Samir, Thompson, Timothy C.
Publicado 2020

A Plasma-Derived Protein-Metabolite Multiplexed Panel for Early-Stage Pancreatic Cancer

por Fahrmann, Johannes F, Bantis, Leonidas E, Capello, Michela, Scelo, Ghislaine, Dennison, Jennifer B, Patel, Nikul, Murage, Eunice, Vykoukal, Jody, Kundnani, Deepali L, Foretova, Lenka, Fabianova, Eleonora, Holcatova, Ivana, Janout, Vladimir, Feng, Ziding, Yip-Schneider, Michele, Zhang, Jianjun, Brand, Randall, Taguchi, Ayumu, Maitra, Anirban, Brennan, Paul, Max Schmidt, C, Hanash, Samir
Publicado 2018

A murine preclinical syngeneic transplantation model for breast cancer precision medicine

por Federico, Lorenzo, Chong, Zechen, Zhang, Dong, McGrail, Daniel J., Zhao, Wei, Jeong, Kang Jin, Vellano, Christopher P., Ju, Zhenlin, Gagea, Mihai, Liu, Shuying, Mitra, Shreya, Dennison, Jennifer B., Lorenzi, Philip L., Cardnell, Robert, Diao, Lixia, Wang, Jing, Lu, Yiling, Byers, Lauren A., Perou, Charles M., Lin, Shiaw-Yih, Mills, Gordon B.
Publicado 2017

Mutational Activation of the NRF2 Pathway Upregulates Kynureninase Resulting in Tumor Immunosuppression and Poor Outcome in Lung Adenocarcinoma

por Fahrmann, Johannes F., Tanaka, Ichidai, Irajizad, Ehsan, Mao, Xiangying, Dennison, Jennifer B., Murage, Eunice, Casabar, Julian, Mayo, Jeffrey, Peng, Qian, Celiktas, Muge, Vykoukal, Jody V., Park, Soyoung, Taguchi, Ayumu, Delgado, Oliver, Tripathi, Satyendra C., Katayama, Hiroyuki, Soto, Luisa Maren Solis, Rodriguez-Canales, Jaime, Behrens, Carmen, Wistuba, Ignacio, Hanash, Samir, Ostrin, Edwin J.
Publicado 2022

Application of Artificial Intelligence to Plasma Metabolomics Profiles to Predict Response to Neoadjuvant Chemotherapy in Triple-Negative Breast Cancer

por Irajizad, Ehsan, Wu, Ranran, Vykoukal, Jody, Murage, Eunice, Spencer, Rachelle, Dennison, Jennifer B., Moulder, Stacy, Ravenberg, Elizabeth, Lim, Bora, Litton, Jennifer, Tripathym, Debu, Valero, Vicente, Damodaran, Senthil, Rauch, Gaiane M., Adrada, Beatriz, Candelaria, Rosalind, White, Jason B., Brewster, Abenaa, Arun, Banu, Long, James P., Do, Kim Anh, Hanash, Sam, Fahrmann, Johannes F.
Publicado 2022

A Comprehensive Search of Non-Canonical Proteins in Non-Small Cell Lung Cancer and Their Impact on the Immune Response

por Irajizad, Ehsan, Fahrmann, Johannes F., Long, James P., Vykoukal, Jody, Kobayashi, Makoto, Capello, Michela, Yu, Chuan-Yih, Cai, Yining, Hsiao, Fu Chung, Patel, Nikul, Park, Soyoung, Peng, Qian, Dennison, Jennifer B., Kato, Taketo, Tai, Mei Chee, Taguchi, Ayumu, Kadara, Humam, Wistuba, Ignacio I., Katayama, Hiroyuki, Do, Kim-Anh, Hanash, Samir M., Ostrin, Edwin J.
Publicado 2022

Quinoline 3-sulfonamides inhibit lactate dehydrogenase A and reverse aerobic glycolysis in cancer cells

por Billiard, Julia, Dennison, Jennifer B, Briand, Jacques, Annan, Roland S, Chai, Deping, Colón, Mariela, Dodson, Christopher S, Gilbert, Seth A, Greshock, Joel, Jing, Junping, Lu, Hong, McSurdy-Freed, Jeanelle E, Orband-Miller, Lisa A, Mills, Gordon B, Quinn, Chad J, Schneck, Jessica L, Scott, Gilbert F, Shaw, Anthony N, Waitt, Gregory M, Wooster, Richard F, Duffy, Kevin J
Publicado 2013

Functional annotation of rare gene aberration drivers of pancreatic cancer

por Tsang, Yiu Huen, Dogruluk, Turgut, Tedeschi, Philip M., Wardwell-Ozgo, Joanna, Lu, Hengyu, Espitia, Maribel, Nair, Nikitha, Minelli, Rosalba, Chong, Zechen, Chen, Fengju, Chang, Qing Edward, Dennison, Jennifer B., Dogruluk, Armel, Li, Min, Ying, Haoqiang, Bertino, Joseph R., Gingras, Marie-Claude, Ittmann, Michael, Kerrigan, John, Chen, Ken, Creighton, Chad J., Eterovic, Karina, Mills, Gordon B., Scott, Kenneth L.
Publicado 2016

CES2 sustains HNF4α expression to promote pancreatic adenocarcinoma progression through an epoxide hydrolase-dependent regulatory loop

por Chen, Yihui, Capello, Michela, Rios Perez, Mayrim V., Vykoukal, Jody V., Roife, David, Kang, Ya'an, Prakash, Laura R., Katayama, Hiroyuki, Irajizad, Ehsan, Fleury, Alia, Ferri-Borgogno, Sammy, Baluya, Dodge L., Dennison, Jennifer B., Do, Kim-Anh, Fiehn, Oliver, Maitra, Anirban, Wang, Huamin, Chiao, Paul J., Katz, Matthew H.G., Fleming, Jason B., Hanash, Samir M., Fahrmann, Johannes F.
Publicado 2021

A blood-based metabolomic signature predictive of risk for pancreatic cancer

por Irajizad, Ehsan, Kenney, Ana, Tang, Tiffany, Vykoukal, Jody, Wu, Ranran, Murage, Eunice, Dennison, Jennifer B., Sans, Marta, Long, James P., Loftus, Maureen, Chabot, John A., Kluger, Michael D., Kastrinos, Fay, Brais, Lauren, Babic, Ana, Jajoo, Kunal, Lee, Linda S., Clancy, Thomas E., Ng, Kimmie, Bullock, Andrea, Genkinger, Jeanine M., Maitra, Anirban, Do, Kim-Anh, Yu, Bin, Wolpin, Brian M., Hanash, Sam, Fahrmann, Johannes F.
Publicado 2023

Exercise Training Reduces the Inflammatory Response and Promotes Intestinal Mucosa-Associated Immunity in Lynch Syndrome

por Deng, Nan, Reyes-Uribe, Laura, Fahrmann, Johannes F., Thoman, Whittney S., Munsell, Mark F., Dennison, Jennifer B., Murage, Eunice, Wu, Ranran, Hawk, Ernest T., Thirumurthi, Selvi, Lynch, Patrick M., Dieli-Conwright, Christina M., Lazar, Alexander J., Jindal, Sonali, Chu, Khoi, Chelvanambi, Manoj, Basen-Engquist, Karen, Li, Yisheng, Wargo, Jennifer A., McAllister, Florencia, Allison, James P., Sharma, Padmanee, Sinha, Krishna M., Hanash, Samir, Gilchrist, Susan C., Vilar, Eduardo
Publicado 2023