A Two-Dimensional Pooling Strategy for Rare Variant Detection on Next-Generation Sequencing Platforms

por Zuzarte, Philip C., Denroche, Robert E., Fehringer, Gordon, Katzov-Eckert, Hagit, Hung, Rayjean J., McPherson, John D.
Publicado 2014

A cancer cell-line titration series for evaluating somatic classification

por Denroche, Robert E., Mullen, Laura, Timms, Lee, Beck, Timothy, Yung, Christina K., Stein, Lincoln, McPherson, John D., Brown, Andrew M. K.
Publicado 2015

Whole-genome sequencing of 20 cholangiocarcinoma cases reveals unique profiles in patients with cirrhosis and primary sclerosing cholangitis

por Holzapfel, Nicholas, Zhang, Amy, Choi, Woo-Jin, Denroche, Robert, Jang, Gunho, Dodd, Anna, Bucur, Roxana, Wilson, Julie, Sapisochin, Gonzalo, Notta, Faiyaz, Grant, Robert C., Gallinger, Steven, Knox, Jennifer J., O’Kane, Grainne M.
Publicado 2023

Pancreatic cancer ascites xenograft–an expeditious model mirroring advanced therapeutic resistant disease

por Golan, Talia, Stossel, Chani, Schvimer, Michael, Atias, Dikla, Halperin, Sharon, Buzhor, Ella, Raitses-Gurevich, Maria, Cohen, Keren, Pri-Chen, Sara, Wilson, Julie, Denroche, Robert E., Lungu, Ilinca, Bartlett, John M.S., Mbabaali, Faridah, Yarden, Yosef, Nataraj, Nishanth Belugali, Gallinger, Steven, Berger, Raanan
Publicado 2017

Whole genomes define concordance of matched primary, xenograft, and organoid models of pancreas cancer

por Gendoo, Deena M. A., Denroche, Robert E., Zhang, Amy, Radulovich, Nikolina, Jang, Gun Ho, Lemire, Mathieu, Fischer, Sandra, Chadwick, Dianne, Lungu, Ilinca M., Ibrahimov, Emin, Cao, Ping-Jiang, Stein, Lincoln D., Wilson, Julie M., Bartlett, John M. S., Tsao, Ming-Sound, Dhani, Neesha, Hedley, David, Gallinger, Steven, Haibe-Kains, Benjamin
Publicado 2019

Patient-derived tumor xenograft and organoid models established from resected pancreatic, duodenal and biliary cancers

por Pham, Nhu-An, Radulovich, Nikolina, Ibrahimov, Emin, Martins-Filho, Sebastiao N., Li, Quan, Pintilie, Melania, Weiss, Jessica, Raghavan, Vibha, Cabanero, Michael, Denroche, Robert E., Wilson, Julie M., Metran-Nascente, Cristiane, Borgida, Ayelet, Hutchinson, Shawn, Dodd, Anna, Begora, Michael, Chadwick, Dianne, Serra, Stefano, Knox, Jennifer J., Gallinger, Steven, Hedley, David W., Muthuswamy, Lakshmi, Tsao, Ming-Sound
Publicado 2021

Intra-Tumoral CD8+ T-Cell Infiltration and PD-L1 Positivity in Homologous Recombination Deficient Pancreatic Ductal Adenocarcinoma

por Golesworthy, Bryn, Wang, Yifan, Tanti, Amanda, Pacis, Alain, Romero, Joan Miguel, Cuggia, Adeline, Domecq, Celine, Bourdel, Guillaume, Denroche, Robert E., Jang, Gun Ho, Grant, Robert C., Borgida, Ayelet, Grünwald, Barbara T., Dodd, Anna, Wilson, Julie M., Bourque, Guillaume, O’Kane, Grainne M., Fischer, Sandra E., Kron, Chelsea Maedler, Fiset, Pierre-Olivier, Omeroglu, Atilla, Foulkes, William D., Gallinger, Steven, Guiot, Marie-Christine, Gao, Zu-Hua, Zogopoulos, George
Publicado 2022

Spectrum of Response to Platinum and PARP Inhibitors in Germline BRCA–Associated Pancreatic Cancer in the Clinical and Preclinical Setting

por Stossel, Chani, Raitses-Gurevich, Maria, Atias, Dikla, Beller, Tamar, Glick Gorman, Yulia, Halperin, Sharon, Peer, Eyal, Denroche, Robert E., Zhang, Amy, Notta, Faiyaz, Wilson, Julie M., O'Kane, Grainne M., Haimov Talmoud, Elina, Amison, Nora, Schvimer, Michael, Salpeter, Seth J., Bar, Vered, Zundelevich, Adi, Tirosh, Itay, Tal, Rotem, Dinstag, Gal, Kinar, Yaron, Eliezer, Yonatan, Ben-David, Uri, Gavert, Nancy S., Straussman, Ravid, Gallinger, Steven J., Berger, Raanan, Golan, Talia
Publicado 2023

Integrative analysis of KRAS wildtype metastatic pancreatic ductal adenocarcinoma reveals mutation and expression-based similarities to cholangiocarcinoma

por Topham, James T., Tsang, Erica S., Karasinska, Joanna M., Metcalfe, Andrew, Ali, Hassan, Kalloger, Steve E., Csizmok, Veronika, Williamson, Laura M., Titmuss, Emma, Nielsen, Karina, Negri, Gian Luca, Spencer Miko, Sandra E., Jang, Gun Ho, Denroche, Robert E., Wong, Hui-li, O’Kane, Grainne M., Moore, Richard A., Mungall, Andrew J., Loree, Jonathan M., Notta, Faiyaz, Wilson, Julie M., Bathe, Oliver F., Tang, Patricia A., Goodwin, Rachel, Morin, Gregg B., Knox, Jennifer J., Gallinger, Steven, Laskin, Janessa, Marra, Marco A., Jones, Steven J. M., Schaeffer, David F., Renouf, Daniel J.
Publicado 2022

A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing

por Alioto, Tyler S., Buchhalter, Ivo, Derdak, Sophia, Hutter, Barbara, Eldridge, Matthew D., Hovig, Eivind, Heisler, Lawrence E., Beck, Timothy A., Simpson, Jared T., Tonon, Laurie, Sertier, Anne-Sophie, Patch, Ann-Marie, Jäger, Natalie, Ginsbach, Philip, Drews, Ruben, Paramasivam, Nagarajan, Kabbe, Rolf, Chotewutmontri, Sasithorn, Diessl, Nicolle, Previti, Christopher, Schmidt, Sabine, Brors, Benedikt, Feuerbach, Lars, Heinold, Michael, Gröbner, Susanne, Korshunov, Andrey, Tarpey, Patrick S., Butler, Adam P., Hinton, Jonathan, Jones, David, Menzies, Andrew, Raine, Keiran, Shepherd, Rebecca, Stebbings, Lucy, Teague, Jon W., Ribeca, Paolo, Giner, Francesc Castro, Beltran, Sergi, Raineri, Emanuele, Dabad, Marc, Heath, Simon C., Gut, Marta, Denroche, Robert E., Harding, Nicholas J., Yamaguchi, Takafumi N., Fujimoto, Akihiro, Nakagawa, Hidewaki, Quesada, Víctor, Valdés-Mas, Rafael, Nakken, Sigve, Vodák, Daniel, Bower, Lawrence, Lynch, Andrew G., Anderson, Charlotte L., Waddell, Nicola, Pearson, John V., Grimmond, Sean M., Peto, Myron, Spellman, Paul, He, Minghui, Kandoth, Cyriac, Lee, Semin, Zhang, John, Létourneau, Louis, Ma, Singer, Seth, Sahil, Torrents, David, Xi, Liu, Wheeler, David A., López-Otín, Carlos, Campo, Elías, Campbell, Peter J., Boutros, Paul C., Puente, Xose S., Gerhard, Daniela S., Pfister, Stefan M., McPherson, John D., Hudson, Thomas J., Schlesner, Matthias, Lichter, Peter, Eils, Roland, Jones, David T. W., Gut, Ivo G.
Publicado 2015