A SWELL time to develop the molecular pharmacology of the volume-regulated anion channel (VRAC)

por Figueroa, Eric E., Denton, Jerod S.
Publicado 2022

Cell cycle– and swelling-induced activation of a Caenorhabditis elegans ClC channel is mediated by CeGLC-7α/β phosphatases

por Rutledge, Eric, Denton, Jerod, Strange, Kevin
Publicado 2002

A 30-year journey from volume-regulated anion currents to molecular structure of the LRRC8 channel

por Strange, Kevin, Yamada, Toshiki, Denton, Jerod S.
Publicado 2019

Malpighian Tubules as Novel Targets for Mosquito Control

por Piermarini, Peter M., Esquivel, Carlos J., Denton, Jerod S.
Publicado 2017

Cryo-EM structures of an LRRC8 chimera with native functional properties reveal heptameric assembly

por Takahashi, Hirohide, Yamada, Toshiki, Denton, Jerod S, Strange, Kevin, Karakas, Erkan
Publicado 2023

GCK-3, a Newly Identified Ste20 Kinase, Binds To and Regulates the Activity of a Cell Cycle–dependent ClC Anion Channel

por Denton, Jerod, Nehrke, Keith, Yin, Xiaoyan, Morrison, Rebecca, Strange, Kevin
Publicado 2005

Pharmacological Validation of an Inward-Rectifier Potassium (Kir) Channel as an Insecticide Target in the Yellow Fever Mosquito Aedes aegypti

por Rouhier, Matthew F., Raphemot, Rene, Denton, Jerod S., Piermarini, Peter M.
Publicado 2014

Pharmacological Inhibition of Inward Rectifier Potassium Channels Induces Lethality in Larval Aedes aegypti

por Rusconi Trigueros, Renata, Hopkins, Corey R., Denton, Jerod S., Piermarini, Peter M.
Publicado 2018

The LRRC8 volume‐regulated anion channel inhibitor, DCPIB, inhibits mitochondrial respiration independently of the channel

por Afzal, Aqeela, Figueroa, Eric E., Kharade, Sujay V., Bittman, Kevin, Matlock, Brittany K., Flaherty, David K., Denton, Jerod S.
Publicado 2019

Abnormal Electroretinogram after Kir7.1 Channel Suppression Suggests Role in Retinal Electrophysiology

por Shahi, Pawan K., Liu, Xinling, Aul, Bryce, Moyer, Andrea, Pattnaik, Akshita, Denton, Jerod, Pillers, De-Ann M., Pattnaik, Bikash R.
Publicado 2017

Kir4.2 mediates proximal potassium effects on glutaminase activity and kidney injury

por Terker, Andrew S., Zhang, Yahua, Arroyo, Juan Pablo, Cao, Shirong, Wang, Suwan, Fan, Xiaofeng, Denton, Jerod S., Zhang, Ming-Zhi, Harris, Raymond C.
Publicado 2022

Discovery, Characterization, and Structure–Activity Relationships of an Inhibitor of Inward Rectifier Potassium (Kir) Channels with Preference for Kir2.3, Kir3.X, and Kir7.1

por Raphemot, Rene, Lonergan, Daniel F., Nguyen, Thuy T., Utley, Thomas, Lewis, L. Michelle, Kadakia, Rishin, Weaver, C. David, Gogliotti, Rocco, Hopkins, Corey, Lindsley, Craig W., Denton, Jerod S.
Publicado 2011

High-Throughput Screening of Myometrial Calcium-Mobilization to Identify Modulators of Uterine Contractility

por Herington, Jennifer L., Swale, Daniel R., Brown, Naoko, Shelton, Elaine L., Choi, Hyehun, Williams, Charles H., Hong, Charles C., Paria, Bibhash C., Denton, Jerod S., Reese, Jeff
Publicado 2015

Eliciting Renal Failure in Mosquitoes with a Small-Molecule Inhibitor of Inward-Rectifying Potassium Channels

por Raphemot, Rene, Rouhier, Matthew F., Hopkins, Corey R., Gogliotti, Rocco D., Lovell, Kimberly M., Hine, Rebecca M., Ghosalkar, Dhairyasheel, Longo, Anthony, Beyenbach, Klaus W., Denton, Jerod S., Piermarini, Peter M.
Publicado 2013

Lactate activation of α-cell K(ATP) channels inhibits glucagon secretion by hyperpolarizing the membrane potential and reducing Ca(2+) entry

por Zaborska, Karolina E., Dadi, Prasanna K., Dickerson, Matthew T., Nakhe, Arya Y., Thorson, Ariel S., Schaub, Charles M., Graff, Sarah M., Stanley, Jade E., Kondapavuluru, Roy S., Denton, Jerod S., Jacobson, David A.
Publicado 2020

Discovery and Characterization of a Potent and Selective Inhibitor of Aedes aegypti Inward Rectifier Potassium Channels

por Raphemot, Rene, Rouhier, Matthew F., Swale, Daniel R., Days, Emily, Weaver, C. David, Lovell, Kimberly M., Konkel, Leah C., Engers, Darren W., Bollinger, Sean F., Hopkins, Corey, Piermarini, Peter M., Denton, Jerod S.
Publicado 2014

G-protein independent coupling of the MC4R to Kir 7.1 in hypothalamic neurons

por Ghamari-Langroudi, Masoud, Digby, Gregory J., Sebag, Julien A., Millhauser, Glenn L., Palomino, Rafael, Matthews, Robert, Gillyard, Taneisha, Panaro, Brandon L., Tough, Iain R., Cox, Helen M., Denton, Jerod S., Cone, Roger D.
Publicado 2015

An insecticide resistance-breaking mosquitocide targeting inward rectifier potassium channels in vectors of Zika virus and malaria

por Swale, Daniel R., Engers, Darren W., Bollinger, Sean R., Gross, Aaron, Inocente, Edna Alfaro, Days, Emily, Kanga, Fariba, Johnson, Reed M., Yang, Liu, Bloomquist, Jeffrey R., Hopkins, Corey R., Piermarini, Peter M., Denton, Jerod S.
Publicado 2016

A selective inhibitor of the sperm-specific potassium channel SLO3 impairs human sperm function

por Lyon, Maximilian, Li, Ping, Ferreira, Juan J., Lazarenko, Roman M., Kharade, Sujay V., Kramer, Meghan, McClenahan, Samantha J., Days, Emily, Bauer, Joshua A., Spitznagel, Brittany D., Weaver, C. David, Borrego Alvarez, Aluet, Puga Molina, Lis C., Lybaert, Pascale, Khambekar, Saayli, Liu, Alicia, Lindsley, Craig W., Denton, Jerod, Santi, Celia M.
Publicado 2023

The inwardly rectifying K(+) channel KIR7.1 controls uterine excitability throughout pregnancy

por McCloskey, Conor, Rada, Cara, Bailey, Elizabeth, McCavera, Samantha, van den Berg, Hugo A, Atia, Jolene, Rand, David A, Shmygol, Anatoly, Chan, Yi-Wah, Quenby, Siobhan, Brosens, Jan J, Vatish, Manu, Zhang, Jie, Denton, Jerod S, Taggart, Michael J, Kettleborough, Catherine, Tickle, David, Jerman, Jeff, Wright, Paul, Dale, Timothy, Kanumilli, Srinivasan, Trezise, Derek J, Thornton, Steve, Brown, Pamela, Catalano, Roberto, Lin, Nan, England, Sarah K, Blanks, Andrew M
Publicado 2014