HIV cure trial mergers: Spotlighting the epigenetics of latency reversal

por Denton, Paul W.
Publicado 2022

Using animal models to overcome temporal, spatial and combinatorial challenges in HIV persistence research

por Denton, Paul W., Søgaard, Ole S., Tolstrup, Martin
Publicado 2016

The role of miR-29a in HIV-1 replication and latency

por Frattari, Giacomo, Aagaard, Lars, Denton, Paul W
Publicado 2017

Impacts of HIV Cure Interventions on Viral Reservoirs in Tissues

por Denton, Paul W., Søgaard, Ole S., Tolstrup, Martin
Publicado 2019

Hypogammaglobulinemia in BLT Humanized Mice – An Animal Model of Primary Antibody Deficiency

por Martinez-Torres, Francisco, Nochi, Tomonori, Wahl, Angela, Garcia, J. Victor, Denton, Paul W.
Publicado 2014

Rectal Transmission of Transmitted/Founder HIV-1 Is Efficiently Prevented by Topical 1% Tenofovir in BLT Humanized Mice

por Chateau, Morgan L., Denton, Paul W., Swanson, Michael D., McGowan, Ian, Garcia, J. Victor
Publicado 2013

Immune checkpoints and the HIV-1 reservoir: proceed with caution

por Olesen, Rikke, Leth, Steffen, Nymann, Rasmus, Østergaard, Lars, Søgaard, Ole S., Denton, Paul W., Tolstrup, Martin
Publicado 2016

Human Breast Milk and Antiretrovirals Dramatically Reduce Oral HIV-1 Transmission in BLT Humanized Mice

por Wahl, Angela, Swanson, Michael D., Nochi, Tomonori, Olesen, Rikke, Denton, Paul W., Chateau, Morgan, Garcia, J. Victor
Publicado 2012

In vivo analysis of highly conserved Nef activities in HIV-1 replication and pathogenesis

por Watkins, Richard L, Zou, Wei, Denton, Paul W, Krisko, John F, Foster, John L, Garcia, J Victor
Publicado 2013

Nef functions in BLT mice to enhance HIV-1 replication and deplete CD4(+)CD8(+) thymocytes

por Zou, Wei, Denton, Paul W, Watkins, Richard L, Krisko, John F, Nochi, Tomonori, Foster, John L, Garcia, J Victor
Publicado 2012

Acute Appendicitis as the Initial Clinical Presentation of Primary HIV-1 Infection

por Schleimann, Mariane H, Leth, Steffen, Krarup, Astrid R, Mortensen, Jesper, Barstad, Bente, Zaccarin, Matthias, Denton, Paul W, Mohey, Rajesh
Publicado 2018

Fimepinostat, a novel dual inhibitor of HDAC and PI3K, effectively reverses HIV-1 latency ex vivo without T cell activation

por Gunst, Jesper D, Kjær, Kathrine, Olesen, Rikke, Rasmussen, Thomas A, Østergaard, Lars, Denton, Paul W, Søgaard, Ole S, Tolstrup, Martin
Publicado 2019

Comparable human reconstitution following Cesium-137 versus X-ray irradiation preconditioning in immunodeficient NOG mice

por Andersen, Anna Halling Folkmar, Nielsen, Stine Sofie Frank, Olesen, Rikke, Harslund, Jakob Le Fèvre, Søgaard, Ole Schmeltz, Østergaard, Lars, Denton, Paul W., Tolstrup, Martin
Publicado 2020

Predicting HIV Pre-exposure Prophylaxis Efficacy for Women using a Preclinical Pharmacokinetic-Pharmacodynamic In Vivo Model

por Wahl, Angela, Ho, Phong T., Denton, Paul W., Garrett, Katy L., Hudgens, Michael G., Swartz, Glenn, O’Neill, Cynthia, Veronese, Fulvia, Kashuba, Angela D., Garcia, J. Victor
Publicado 2017

Antiretroviral Pre-exposure Prophylaxis Prevents Vaginal Transmission of HIV-1 in Humanized BLT Mice

por Denton, Paul W, Estes, Jacob D, Sun, Zhifeng, Othieno, Florence A, Wei, Bangdong L, Wege, Anja K, Powell, Daniel A, Payne, Deborah, Haase, Ashley T, Garcia, J. Victor
Publicado 2008

Systemic Administration of Antiretrovirals Prior to Exposure Prevents Rectal and Intravenous HIV-1 Transmission in Humanized BLT Mice

por Denton, Paul W., Krisko, John F., Powell, Daniel A., Mathias, Melissa, Kwak, Youn Tae, Martinez-Torres, Francisco, Zou, Wei, Payne, Deborah A., Estes, Jacob D., Garcia, J. Victor
Publicado 2010

Intrarectal transmission, systemic infection, and CD4(+) T cell depletion in humanized mice infected with HIV-1

por Sun, Zhifeng, Denton, Paul W., Estes, Jacob D., Othieno, Florence A., Wei, Bangdong L., Wege, Anja K., Melkus, Michael W., Padgett-Thomas, Angela, Zupancic, Mary, Haase, Ashley T., Garcia, J. Victor
Publicado 2007

Administration of Panobinostat Is Associated with Increased IL-17A mRNA in the Intestinal Epithelium of HIV-1 Patients

por Bjerg Christensen, Ane, Dige, Anders, Vad-Nielsen, Johan, Brinkmann, Christel R., Bendix, Mia, Østergaard, Lars, Tolstrup, Martin, Søgaard, Ole S., Rasmussen, Thomas A., Randel Nyengaard, Jens, Agnholt, Jørgen, Denton, Paul W.
Publicado 2015

CD169 (Siglec-1) as a Robust Human Cell Biomarker of Toll-Like Receptor 9 Agonist Immunotherapy

por Lende, Stine Sofie Frank, Pahus, Marie Høst, Monrad, Ida, Olesen, Rikke, Mahr, Anna R., Vibholm, Line K., Østergaard, Lars, Søgaard, Ole Schmeltz, Andersen, Anna Halling Folkmar, Denton, Paul W., Tolstrup, Martin
Publicado 2022

Treatment of HIV-Infected Individuals with the Histone Deacetylase Inhibitor Panobinostat Results in Increased Numbers of Regulatory T Cells and Limits Ex Vivo Lipopolysaccharide-I...

por Brinkmann, Christel Rothe, Højen, Jesper Falkesgaard, Rasmussen, Thomas Aagaard, Kjær, Anne Sofie, Olesen, Rikke, Denton, Paul W., Østergaard, Lars, Ouyang, Zhengyu, Lichterfeld, Mathias, Yu, Xu, Søgaard, Ole Schmeltz, Dinarello, Charles, Tolstrup, Martin
Publicado 2018