Setting Up a Bioluminescence Resonance Energy Transfer High throughput Screening Assay to Search for Protein/Protein Interaction Inhibitors in Mammalian Cells

por Couturier, Cyril, Deprez, Benoit
Publicado 2012

Insulin-Degrading Enzyme, an Under-Estimated Potential Target to Treat Cancer?

por Lesire, Laetitia, Leroux, Florence, Deprez-Poulain, Rebecca, Deprez, Benoit
Publicado 2022

Migration study of phthalates from non-food plastic containers used in food preservation

por Songue Same, Olivier, Nobosse, Pierre, Ngolong Ngea, Guillaume Legrand, Piveteau, Catherine, Lemdani, Mohamed, Kamga, Richard, Deprez, Benoit
Publicado 2023

Molecular Design in Practice: A Review of Selected Projects in a French Research Institute That Illustrates the Link between Chemical Biology and Medicinal Chemistry

por Deprez, Benoit, Bosc, Damien, Charton, Julie, Couturier, Cyril, Deprez-Poulain, Rebecca, Flipo, Marion, Leroux, Florence, Villemagne, Baptiste, Willand, Nicolas
Publicado 2021

Rapid and Efficient Access to Novel Bio-Inspired 3-Dimensional Tricyclic SpiroLactams as Privileged Structures via Meyers’ Lactamization

por Tangara, Salia, Faïon, Léo, Piveteau, Catherine, Capet, Frédéric, Godelier, Romain, Michel, Marion, Flipo, Marion, Deprez, Benoit, Willand, Nicolas, Villemagne, Baptiste
Publicado 2023

Designing Focused Chemical Libraries Enriched in Protein-Protein Interaction Inhibitors using Machine-Learning Methods

por Reynès, Christelle, Host, Hélène, Camproux, Anne-Claude, Laconde, Guillaume, Leroux, Florence, Mazars, Anne, Deprez, Benoit, Fahraeus, Robin, Villoutreix, Bruno O., Sperandio, Olivier
Publicado 2010

Rescue of nonsense mutations by amlexanox in human cells

por Gonzalez-Hilarion, Sara, Beghyn, Terence, Jia, Jieshuang, Debreuck, Nadège, Berte, Gonzague, Mamchaoui, Kamel, Mouly, Vincent, Gruenert, Dieter C, Déprez, Benoit, Lejeune, Fabrice
Publicado 2012

The use or generation of biomedical data and existing medicines to discover and establish new treatments for patients with rare diseases – recommendations of the IRDiRC Data Mining...

por Southall, Noel T, Natarajan, Madhusudan, Lau, Lilian Pek Lian, Jonker, Anneliene Hechtelt, Deprez, Benoît, Guilliams, Tim, Hunter, Lawrence, Rademaker, Carin MA, Hivert, Virginie, Ardigò, Diego
Publicado 2019

High-Throughput Quantitative Screening of Glucose-Stimulated Insulin Secretion and Insulin Content Using Automated MALDI-TOF Mass Spectrometry

por Delannoy, Clément Philippe, Heuson, Egon, Herledan, Adrien, Oger, Frederik, Thiroux, Bryan, Chevalier, Mickaël, Gromada, Xavier, Rolland, Laure, Froguel, Philippe, Deprez, Benoit, Paul, Sébastien, Annicotte, Jean-Sébastien
Publicado 2023

Development and implementation of a cell-based assay to discover agonists of the nuclear receptor REV-ERBα

por Hering, Yuliya, Berthier, Alexandre, Duez, Helene, Lefebvre, Philippe, Deprez, Benoit, Gribbon, Philip, Wolf, Markus, Reinshagen, Jeanette, Halley, Francoise, Hannemann, Juliane, Böger, Rainer, Staels, Bart, Gul, Sheraz
Publicado 2018

Farnesoid X Receptor Activation in Brain Alters Brown Adipose Tissue Function via the Sympathetic System

por Deckmyn, Benjamin, Domenger, Dorothée, Blondel, Chloé, Ducastel, Sarah, Nicolas, Emilie, Dorchies, Emilie, Caron, Emilie, Charton, Julie, Vallez, Emmanuelle, Deprez, Benoit, Annicotte, Jean-Sébastien, Lestavel, Sophie, Tailleux, Anne, Magnan, Christophe, Staels, Bart, Bantubungi, Kadiombo
Publicado 2022

Exploring the Antitubercular Activity of Anthranilic Acid Derivatives: From MabA (FabG1) Inhibition to Intrabacterial Acidification

por Faïon, Léo, Djaout, Kamel, Pintiala, Catalin, Piveteau, Catherine, Leroux, Florence, Biela, Alexandre, Slupek, Stéphanie, Antoine, Rudy, Záhorszká, Monika, Cantrelle, Francois-Xavier, Hanoulle, Xavier, Korduláková, Jana, Deprez, Benoit, Willand, Nicolas, Baulard, Alain R., Flipo, Marion
Publicado 2023

Tricyclic SpiroLactams Kill Mycobacteria In Vitro and In Vivo by Inhibiting Type II NADH Dehydrogenases

por Dam, Sushovan, Tangara, Salia, Hamela, Claire, Hattabi, Theo, Faïon, Léo, Carre, Paul, Antoine, Rudy, Herledan, Adrien, Leroux, Florence, Piveteau, Catherine, Eveque, Maxime, Flipo, Marion, Deprez, Benoit, Kremer, Laurent, Willand, Nicolas, Villemagne, Baptiste, Hartkoorn, Ruben C.
Publicado 2022

Structural activation of the transcriptional repressor EthR from Mycobacterium tuberculosis by single amino acid change mimicking natural and synthetic ligands

por Carette, Xavier, Blondiaux, Nicolas, Willery, Eve, Hoos, Sylviane, Lecat-Guillet, Nathalie, Lens, Zoé, Wohlkönig, Alexandre, Wintjens, René, Soror, Sameh H., Frénois, Frédéric, Dirié, Bertrand, Villeret, Vincent, England, Patrick, Lippens, Guy, Deprez, Benoit, Locht, Camille, Willand, Nicolas, Baulard, Alain R.
Publicado 2012

Novel dithiocarbamates selectively inhibit 3CL protease of SARS-CoV-2 and other coronaviruses

por Brier, Lucile, Hassan, Haitham, Hanoulle, Xavier, Landry, Valerie, Moschidi, Danai, Desmarets, Lowiese, Rouillé, Yves, Dumont, Julie, Herledan, Adrien, Warenghem, Sandrine, Piveteau, Catherine, Carré, Paul, Ikherbane, Sarah, Cantrelle, François-Xavier, Dupré, Elian, Dubuisson, Jean, Belouzard, Sandrine, Leroux, Florence, Deprez, Benoit, Charton, Julie
Publicado 2023

Combination therapy for tuberculosis treatment: pulmonary administration of ethionamide and booster co-loaded nanoparticles

por Costa-Gouveia, Joana, Pancani, Elisabetta, Jouny, Samuel, Machelart, Arnaud, Delorme, Vincent, Salzano, Giuseppina, Iantomasi, Raffaella, Piveteau, Catherine, Queval, Christophe J., Song, Ok-Ryul, Flipo, Marion, Deprez, Benoit, Saint-André, Jean-Paul, Hureaux, José, Majlessi, Laleh, Willand, Nicolas, Baulard, Alain, Brodin, Priscille, Gref, Ruxandra
Publicado 2017

Publisher Correction: Combination therapy for tuberculosis treatment: pulmonary administration of ethionamide and booster co-loaded nanoparticles

por Costa-Gouveia, Joana, Pancani, Elisabetta, Jouny, Samuel, Machelart, Arnaud, Delorme, Vincent, Salzano, Giuseppina, Iantomasi, Raffaella, Piveteau, Catherine, Queval, Christophe J., Song, Ok-Ryul, Flipo, Marion, Deprez, Benoit, Saint-André, Jean-Paul, Hureaux, José, Majlessi, Laleh, Willand, Nicolas, Baulard, Alain, Brodin, Priscille, Gref, Ruxandra
Publicado 2018

Pyridylpiperazine-based allosteric inhibitors of RND-type multidrug efflux pumps

por Plé, Coline, Tam, Heng-Keat, Vieira Da Cruz, Anais, Compagne, Nina, Jiménez-Castellanos, Juan-Carlos, Müller, Reinke T., Pradel, Elizabeth, Foong, Wuen Ee, Malloci, Giuliano, Ballée, Alexia, Kirchner, Moritz A., Moshfegh, Parisa, Herledan, Adrien, Herrmann, Andrea, Deprez, Benoit, Willand, Nicolas, Vargiu, Attilio Vittorio, Pos, Klaas M., Flipo, Marion, Hartkoorn, Ruben C.
Publicado 2022

Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme

por Zhang, Zhening, Liang, Wenguang G, Bailey, Lucas J, Tan, Yong Zi, Wei, Hui, Wang, Andrew, Farcasanu, Mara, Woods, Virgil A, McCord, Lauren A, Lee, David, Shang, Weifeng, Deprez-Poulain, Rebecca, Deprez, Benoit, Liu, David R, Koide, Akiko, Koide, Shohei, Kossiakoff, Anthony A, Li, Sheng, Carragher, Bridget, Potter, Clinton S, Tang, Wei-Jen
Publicado 2018

BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr(348) phosphorylation

por Sartori, Maxime, Mendes, Tiago, Desai, Shruti, Lasorsa, Alessia, Herledan, Adrien, Malmanche, Nicolas, Mäkinen, Petra, Marttinen, Mikael, Malki, Idir, Chapuis, Julien, Flaig, Amandine, Vreulx, Anaïs-Camille, Ciancia, Marion, Amouyel, Philippe, Leroux, Florence, Déprez, Benoit, Cantrelle, François-Xavier, Maréchal, Damien, Pradier, Laurent, Hiltunen, Mikko, Landrieu, Isabelle, Kilinc, Devrim, Herault, Yann, Laporte, Jocelyn, Lambert, Jean-Charles
Publicado 2019