Structural Basis for Cyclic Py-Im Polyamide Allosteric Inhibition of Nuclear Receptor Binding

por Chenoweth, David M., Dervan, Peter B.
Publicado 2010

A sequence-specific DNA binding small molecule triggers the release of immunogenic signals and phagocytosis in a model of B-cell lymphoma

por Kang, JeenJoo S., Dervan, Peter B.
Publicado 2015

Sequence specific suppression of androgen receptor–DNA binding in vivo by a Py-Im polyamide

por Kurmis, Alexis A, Dervan, Peter B
Publicado 2019

Microwave Assisted Synthesis of Py-Im Polyamides

por Puckett, James W., Green, Joshua T., Dervan, Peter B.
Publicado 2012

Enhancing the cellular uptake of Py–Im polyamides through next-generation aryl turns

por Meier, Jordan L., Montgomery, David C., Dervan, Peter B.
Publicado 2012

Design of Sequence-Specific DNA Binding Molecules for DNA Methyltransferase Inhibition

por Kang, JeenJoo S., Meier, Jordan L., Dervan, Peter B.
Publicado 2014

Tumor Xenograft Uptake of a Pyrrole–Imidazole (Py-Im) Polyamide Varies as a Function of Cell Line Grafted

por Raskatov, Jevgenij A., Szablowski, Jerzy O., Dervan, Peter B.
Publicado 2014

Improved nuclear localization of DNA-binding polyamides

por Nickols, Nicholas G., Jacobs, Claire S., Farkas, Michelle E., Dervan, Peter B.
Publicado 2007

Synthesis of Cyclic Py-Im Polyamide Libraries

por Li, Benjamin C., Montgomery, David C., Puckett, James W., Dervan, Peter B.
Publicado 2012

Guiding the Design of Synthetic DNA-Binding Molecules with Massively Parallel Sequencing

por Meier, Jordan L., Yu, Abigail S., Korf, Ian, Segal, David J., Dervan, Peter B.
Publicado 2012

RNA polymerase II trapped on a molecular treadmill: Structural basis of persistent transcriptional arrest by a minor groove DNA binder

por Oh, Juntaek, Jia, Tiezheng, Xu, Jun, Chong, Jenny, Dervan, Peter B., Wang, Dong
Publicado 2022

Unanticipated differences between α- and γ-diaminobutyric acid-linked hairpin polyamide-alkylator conjugates

por Tsai, Sherry M., Farkas, Michelle E., Chou, C. James, Gottesfeld, Joel M., Dervan, Peter B.
Publicado 2007

Expanding the Repertoire of Natural Product-Inspired Ring Pairs for Molecular Recognition of DNA

por Muzikar, Katy A., Meier, Jordan L., Gubler, Daniel A., Raskatov, Jevgenij A., Dervan, Peter B.
Publicado 2011

Characterization and Solubilization of Pyrrole–Imidazole Polyamide Aggregates

por Hargrove, Amanda E., Raskatov, Jevgenij A., Meier, Jordan L., Montgomery, David C., Dervan, Peter B.
Publicado 2012

Single position substitution of hairpin pyrrole-imidazole polyamides imparts distinct DNA-binding profiles across the human genome

por Finn, Paul B., Bhimsaria, Devesh, Ali, Asfa, Eguchi, Asuka, Ansari, Aseem Z., Dervan, Peter B.
Publicado 2020

Interference with DNA repair after ionizing radiation by a pyrrole-imidazole polyamide

por Diaz-Perez, Silvia, Kane, Nathanael, Kurmis, Alexis A., Yang, Fei, Kummer, Nicolas T., Dervan, Peter B., Nickols, Nicholas G.
Publicado 2018

Single-dose pharmacokinetic and toxicity analysis of pyrrole–imidazole polyamides in mice

por Synold, Timothy W., Xi, Bixin, Wu, Jun, Yen, Yun, Li, Benjamin C., Yang, Fei, Phillips, John W., Nickols, Nicholas G., Dervan, Peter B.
Publicado 2012

Animal Toxicity of Hairpin Pyrrole-Imidazole Polyamides Varies with the Turn Unit

por Yang, Fei, Nickols, Nicholas G., Li, Benjamin C., Szablowski, Jerzy O., Hamilton, Shari R., Meier, Jordan L., Wang, Chieh-Mei, Dervan, Peter B.
Publicado 2013

Replication stress by Py–Im polyamides induces a non-canonical ATR-dependent checkpoint response

por Martínez, Thomas F., Phillips, John W., Karanja, Kenneth K., Polaczek, Piotr, Wang, Chieh-Mei, Li, Benjamin C., Campbell, Judith L., Dervan, Peter B.
Publicado 2014

Tumor Repression of VCaP Xenografts by a Pyrrole-Imidazole Polyamide

por Hargrove, Amanda E., Martinez, Thomas F., Hare, Alissa A., Kurmis, Alexis A., Phillips, John W., Sud, Sudha, Pienta, Kenneth J, Dervan, Peter B.
Publicado 2015