OTHR-38. The development of patient-derived models of pediatric brain tumors

por Messiaen, Julie, Derweduwe, Marleen, Claeys, Annelies, Solie, Lien, Sciot, Raf, Bempt, Isabelle Vanden, Devleeschouwer, Steven, Van Calenbergh, Frank, De Vloo, Philippe, Depreitere, Bart, Jacobs, Sandra, De Smet, Frederik
Publicado 2022

OTHR-39. Extraneural spreading of a diffuse leptomeningeal glioneuronal tumor in a child: patient-derived models show sensitivity to vinblastin and trametinib

por Messiaen, Julie, Claeys, Annelies, Shetty, Aniket, Spans, Lien, Derweduwe, Marleen, Uyttebroeck, Anne, Depreitere, Bart, Bempt, Isabelle Vanden, Sciot, Raf, Ligon, Keith, Jones, David, Jacobs, Sandra, De Smet, Frederik
Publicado 2022

Generation of patient-derived models from a metastatic pediatric diffuse leptomeningeal glioneuronal tumor with KIAA1549::BRAF fusion

por Messiaen, Julie, Claeys, Annelies, Shetty, Aniket, Spans, Lien, Derweduwe, Marleen, Uyttebroeck, Anne, Depreitere, Bart, Vanden Bempt, Isabelle, Sciot, Raf, Ligon, Keith L., Jones, David T. W., Jacobs, Sandra A., De Smet, Frederik
Publicado 2022

GBM tumors are heterogeneous in their fatty acid metabolism and modulating fatty acid metabolism sensitizes cancer cells derived from recurring GBM tumors to temozolomide

por Parik, Sweta, Fernández-García, Juan, Lodi, Francesca, De Vlaminck, Karen, Derweduwe, Marleen, De Vleeschouwer, Steven, Sciot, Raf, Geens, Wietse, Weng, Linqian, Bosisio, Francesca Maria, Bergers, Gabriele, Duerinck, Johnny, De Smet, Frederick, Lambrechts, Diether, Van Ginderachter, Jo A., Fendt, Sarah-Maria
Publicado 2022

Reduced Levels of Misfolded and Aggregated Mutant p53 by Proteostatic Activation

por Naus, Evelyne, Derweduwe, Marleen, Lampi, Youlia, Claeys, Annelies, Pauwels, Jarne, Langenberg, Tobias, Claes, Filip, Xu, Jie, Haemels, Veerle, Atak, Zeynep Kalender, van der Kant, Rob, Van Durme, Joost, De Baets, Greet, Ligon, Keith L., Fiers, Mark, Gevaert, Kris, Aerts, Stein, Rousseau, Frederic, Schymkowitz, Joost, De Smet, Frederik
Publicado 2023

Single‐cell profiling and zebrafish avatars reveal LGALS1 as immunomodulating target in glioblastoma

por Finotto, Lise, Cole, Basiel, Giese, Wolfgang, Baumann, Elisabeth, Claeys, Annelies, Vanmechelen, Maxime, Decraene, Brecht, Derweduwe, Marleen, Dubroja Lakic, Nikolina, Shankar, Gautam, Nagathihalli Kantharaju, Madhu, Albrecht, Jan Philipp, Geudens, Ilse, Stanchi, Fabio, Ligon, Keith L, Boeckx, Bram, Lambrechts, Diether, Harrington, Kyle, Van Den Bosch, Ludo, De Vleeschouwer, Steven, De Smet, Frederik, Gerhardt, Holger
Publicado 2023