Purinergic and Calcium Signaling in Macrophage Function and Plasticity

por Desai, Bimal N., Leitinger, Norbert
Publicado 2014

Editorial: TRP Channels in Inflammation and Immunity

por Partida-Sanchez, Santiago, Desai, Bimal N., Schwab, Albrecht, Zierler, Susanna
Publicado 2021

Revisiting multimodal activation and channel properties of Pannexin 1

por Chiu, Yu-Hsin, Schappe, Michael S., Desai, Bimal N., Bayliss, Douglas A.
Publicado 2018

A high-conductance chemo-optogenetic system based on the vertebrate channel Trpa1b

por Lam, Pui-Ying, Mendu, Suresh K., Mills, Robert W., Zheng, Baohui, Padilla, Hugo, Milan, David J., Desai, Bimal N., Peterson, Randall T.
Publicado 2017

Macrophage phenotype and bioenergetics are controlled by oxidized phospholipids identified in lean and obese adipose tissue

por Serbulea, Vlad, Upchurch, Clint M., Schappe, Michael S., Voigt, Paxton, DeWeese, Dory E., Desai, Bimal N., Meher, Akshaya K., Leitinger, Norbert
Publicado 2018

Caspase-11 Controls Interleukin-1β Release through Degradation of TRPC1

por Py, Bénédicte F., Jin, Mingzhi, Desai, Bimal N., Penumaka, Anirudh, Zhu, Hong, Kober, Maike, Dietrich, Alexander, Lipinski, Marta M., Henry, Thomas, Clapham, David E., Yuan, Junying
Publicado 2014

Macrophage acetyl-CoA carboxylase regulates acute inflammation through control of glucose and lipid metabolism

por Yeudall, Scott, Upchurch, Clint M., Seegren, Philip V., Pavelec, Caitlin M., Greulich, Jan, Lemke, Michael C., Harris, Thurl E., Desai, Bimal N., Hoehn, Kyle L., Leitinger, Norbert
Publicado 2022

Analogs of FTY720 inhibit TRPM7 but not S1PRs and exert multimodal anti-inflammatory effects

por Busey, Gregory W., Manjegowda, Mohan C., Huang, Tao, Iobst, Wesley H., Naphade, Shardul S., Kennedy, Joel A., Doyle, Catherine A., Seegren, Philip V., Lynch, Kevin R., Desai, Bimal N.
Publicado 2023

Neuronal hyperexcitability is a DLK-dependent trigger of herpes simplex virus reactivation that can be induced by IL-1

por Cuddy, Sean R, Schinlever, Austin R, Dochnal, Sara, Seegren, Philip V, Suzich, Jon, Kundu, Parijat, Downs, Taylor K, Farah, Mina, Desai, Bimal N, Boutell, Chris, Cliffe, Anna R
Publicado 2020

Efferocytosis requires periphagosomal Ca(2+)-signaling and TRPM7-mediated electrical activity

por Schappe, Michael S., Stremska, Marta E., Busey, Gregory W., Downs, Taylor K., Seegren, Philip V., Mendu, Suresh K., Flegal, Zachary, Doyle, Catherine A., Stipes, Eric J., Desai, Bimal N.
Publicado 2022

Reduced mitochondrial calcium uptake in macrophages is a major driver of inflammaging

por Seegren, Philip V., Harper, Logan R., Downs, Taylor K., Zhao, Xiao-Yu, Viswanathan, Shivapriya B., Stremska, Marta E., Olson, Rachel J., Kennedy, Joel, Ewald, Sarah E., Kumar, Pankaj, Desai, Bimal N.
Publicado 2023

Mitochondrial Ca(2+) Signaling Is an Electrometabolic Switch to Fuel Phagosome Killing

por Seegren, Philip V., Downs, Taylor K., Stremska, Marta E., Harper, Logan R., Cao, Ruofan, Olson, Rachel J., Upchurch, Clint M., Doyle, Catherine A., Kennedy, Joel, Stipes, Eric L., Leitinger, Norbert, Periasamy, Ammasi, Desai, Bimal N.
Publicado 2020

Hematopoietic pannexin 1 function is critical for neuropathic pain

por Weaver, Janelle L., Arandjelovic, Sanja, Brown, Gregory, K. Mendu, Suresh, S. Schappe, Michael, Buckley, Monica W., Chiu, Yu-Hsin, Shu, Shaofang, Kim, Jin K., Chung, Joyce, Krupa, Julia, Jevtovic-Todorovic, Vesna, Desai, Bimal N., Ravichandran, Kodi S., Bayliss, Douglas A.
Publicado 2017

Deacetylation as a receptor-regulated direct activation switch for pannexin channels

por Chiu, Yu-Hsin, Medina, Christopher B., Doyle, Catherine A., Zhou, Ming, Narahari, Adishesh K., Sandilos, Joanna K., Gonye, Elizabeth C., Gao, Hong-Yu, Guo, Shih Yi, Parlak, Mahmut, Lorenz, Ulrike M., Conrads, Thomas P., Desai, Bimal N., Ravichandran, Kodi S., Bayliss, Douglas A.
Publicado 2021

Distinct insulin granule subpopulations implicated in the secretory pathology of diabetes types 1 and 2

por Kreutzberger, Alex J B, Kiessling, Volker, Doyle, Catherine A, Schenk, Noah, Upchurch, Clint M, Elmer-Dixon, Margaret, Ward, Amanda E, Preobraschenski, Julia, Hussein, Syed S, Tomaka, Weronika, Seelheim, Patrick, Kattan, Iman, Harris, Megan, Liang, Binyong, Kenworthy, Anne K, Desai, Bimal N, Leitinger, Norbert, Anantharam, Arun, Castle, J David, Tamm, Lukas K
Publicado 2020

Adaptive thermogenesis in brown adipose tissue involves activation of pannexin-1 channels

por Senthivinayagam, Subramanian, Serbulea, Vlad, Upchurch, Clint M., Polanowska-Grabowska, Renata, Mendu, Suresh K., Sahu, Srabani, Jayaguru, Prathiba, Aylor, Kevin W., Chordia, Mahendra D., Steinberg, Limor, Oberholtzer, Nathaniel, Uchiyama, Seichii, Inada, Noriko, Lorenz, Ulrike M., Harris, Thurl E., Keller, Susanna R., Meher, Akshaya K., Kadl, Alexandra, Desai, Bimal N., Kundu, Bijoy K., Leitinger, Norbert
Publicado 2020