Distinct transcriptional programs stratify ovarian cancer cell lines into the five major histological subtypes

por Barnes, Bethany M., Nelson, Louisa, Tighe, Anthony, Burghel, George J., Lin, I-Hsuan, Desai, Sudha, McGrail, Joanne C., Morgan, Robert D., Taylor, Stephen S.
Publicado 2021

Exploiting a living biobank to delineate mechanisms underlying disease-specific chromosome instability

por Nelson, Louisa, Barnes, Bethany M., Tighe, Anthony, Littler, Samantha, Coulson-Gilmer, Camilla, Golder, Anya, Desai, Sudha, Morgan, Robert D., McGrail, Joanne C., Taylor, Stephen S.
Publicado 2023

Replication catastrophe is responsible for intrinsic PAR glycohydrolase inhibitor-sensitivity in patient-derived ovarian cancer models

por Coulson-Gilmer, Camilla, Morgan, Robert D., Nelson, Louisa, Barnes, Bethany M., Tighe, Anthony, Wardenaar, René, Spierings, Diana C. J., Schlecht, Helene, Burghel, George J., Foijer, Floris, Desai, Sudha, McGrail, Joanne C., Taylor, Stephen S.
Publicado 2021

A GPBAR1 (TGR5) Small Molecule Agonist Shows Specific Inhibitory Effects on Myeloid Cell Activation In Vitro and Reduces Experimental Autoimmune Encephalitis (EAE) In Vivo

por Lewis, Nuruddeen D., Patnaude, Lori A., Pelletier, Josephine, Souza, Donald J., Lukas, Susan M., King, F. James, Hill, Jonathan D., Stefanopoulos, Dimitria E., Ryan, Kelli, Desai, Sudha, Skow, Donna, Kauschke, Stefan G., Broermann, Andre, Kuzmich, Daniel, Harcken, Christian, Hickey, Eugene R., Modis, Louise K.
Publicado 2014

A living biobank of ovarian cancer ex vivo models reveals profound mitotic heterogeneity

por Nelson, Louisa, Tighe, Anthony, Golder, Anya, Littler, Samantha, Bakker, Bjorn, Moralli, Daniela, Murtuza Baker, Syed, Donaldson, Ian J., Spierings, Diana C. J., Wardenaar, René, Neale, Bethanie, Burghel, George J., Winter-Roach, Brett, Edmondson, Richard, Clamp, Andrew R., Jayson, Gordon C., Desai, Sudha, Green, Catherine M., Hayes, Andy, Foijer, Floris, Morgan, Robert D., Taylor, Stephen S.
Publicado 2020