Identification of Insulin Receptor Splice Variant B in Neurons by in situ Detection in Human Brain Samples

por Spencer, Brian, Rank, Logan, Metcalf, Jeff, Desplats, Paula
Publicado 2018

Evaluation of Biochemical and Epigenetic Measures of Peripheral Brain-Derived Neurotrophic Factor (BDNF) as a Biomarker in Huntington’s Disease Patients

por Gutierrez, Ashley, Corey-Bloom, Jody, Thomas, Elizabeth A., Desplats, Paula
Publicado 2020

Combined exposure to Maneb and Paraquat alters transcriptional regulation of neurogenesis-related genes in mice models of Parkinson’s disease

por Desplats, Paula, Patel, Pruthul, Kosberg, Kori, Mante, Michael, Patrick, Christina, Rockenstein, Edward, Fujita, Masayo, Hashimoto, Makoto, Masliah, Eliezer
Publicado 2012

Epigenetic Alterations in the Brain Associated with HIV-1 Infection and Methamphetamine Dependence

por Desplats, Paula, Dumaop, Wilmar, Cronin, Peter, Gianella, Sara, Woods, Steven, Letendre, Scott, Smith, David, Masliah, Eliezer, Grant, Igor
Publicado 2014

Combination of alpha-synuclein immunotherapy with anti-inflammatory treatment in a transgenic mouse model of multiple system atrophy

por Valera, Elvira, Spencer, Brian, Fields, Jerel A., Trinh, Ivy, Adame, Anthony, Mante, Michael, Rockenstein, Edward, Desplats, Paula, Masliah, Eliezer
Publicado 2017

Selective Molecular Alterations in the Autophagy Pathway in Patients with Lewy Body Disease and in Models of α-Synucleinopathy

por Crews, Leslie, Spencer, Brian, Desplats, Paula, Patrick, Christina, Paulino, Amy, Rockenstein, Edward, Hansen, Lawrence, Adame, Anthony, Galasko, Douglas, Masliah, Eliezer
Publicado 2010

Neuroprotective effects of the immunomodulatory drug FK506 in a model of HIV1-gp120 neurotoxicity

por Fields, Jerel A., Overk, Cassia, Adame, Anthony, Florio, Jazmin, Mante, Michael, Pineda, Andrea, Desplats, Paula, Rockenstein, Edward, Achim, Cristian, Masliah, Eliezer
Publicado 2016

Hippocampal neuronal cells that accumulate α-synuclein fragments are more vulnerable to Aβ oligomer toxicity via mGluR5 – implications for dementia with Lewy bodies

por Overk, Cassia R, Cartier, Anna, Shaked, Gideon, Rockenstein, Edward, Ubhi, Kiren, Spencer, Brian, Price, Diana L, Patrick, Christina, Desplats, Paula, Masliah, Eliezer
Publicado 2014

Neuropeptide Treatment with Cerebrolysin Enhances the Survival of Grafted Neural Stem Cell in an α-Synuclein Transgenic Model of Parkinson’s Disease

por Rockenstein, Edward, Desplats, Paula, Ubhi, Kiren, Mante, Michael, Florio, Jazmin, Adame, Anthony, Winter, Stefan, Brandstaetter, Hemma, Meier, Dieter, Moessler, Herbert, Masliah, Eliezer
Publicado 2016

MicroRNA-101 Modulates Autophagy and Oligodendroglial Alpha-Synuclein Accumulation in Multiple System Atrophy

por Valera, Elvira, Spencer, Brian, Mott, Jennifer, Trejo, Margarita, Adame, Anthony, Mante, Michael, Rockenstein, Edward, Troncoso, Juan C., Beach, Thomas G., Masliah, Eliezer, Desplats, Paula
Publicado 2017

Transcriptomic profiling of sporadic Alzheimer’s disease patients

por Caldwell, Andrew B., Anantharaman, Balaji G., Ramachandran, Srinivasan, Nguyen, Phuong, Liu, Qing, Trinh, Ivy, Galasko, Douglas R., Desplats, Paula A., Wagner, Steven L., Subramaniam, Shankar
Publicado 2022

ESCRT-mediated Uptake and Degradation of Brain-targeted α-synuclein Single Chain Antibody Attenuates Neuronal Degeneration In Vivo

por Spencer, Brian, Emadi, Sharareh, Desplats, Paula, Eleuteri, Simona, Michael, Sarah, Kosberg, Kori, Shen, Jay, Rockenstein, Edward, Patrick, Christina, Adame, Anthony, Gonzalez, Tania, Sierks, Michael, Masliah, Eliezer
Publicado 2014

TOM40 Mediates Mitochondrial Dysfunction Induced by α-Synuclein Accumulation in Parkinson’s Disease

por Bender, Andreas, Desplats, Paula, Spencer, Brian, Rockenstein, Edward, Adame, Anthony, Elstner, Matthias, Laub, Christoph, Mueller, Sarina, Koob, Andrew O., Mante, Michael, Pham, Emily, Klopstock, Thomas, Masliah, Eliezer
Publicado 2013

Mechanisms of Hybrid Oligomer Formation in the Pathogenesis of Combined Alzheimer's and Parkinson's Diseases

por Tsigelny, Igor F., Crews, Leslie, Desplats, Paula, Shaked, Gideon M., Sharikov, Yuriy, Mizuno, Hideya, Spencer, Brian, Rockenstein, Edward, Trejo, Margarita, Platoshyn, Oleksandr, Yuan, Jason X.-J., Masliah, Eliezer
Publicado 2008

Alterations in mGluR5 Expression and Signaling in Lewy Body Disease and in Transgenic Models of Alpha-Synucleinopathy – Implications for Excitotoxicity

por Price, Diana L., Rockenstein, Edward, Ubhi, Kiren, Phung, Van, MacLean-Lewis, Natalie, Askay, David, Cartier, Anna, Spencer, Brian, Patrick, Christina, Desplats, Paula, Ellisman, Mark H., Masliah, Eliezer
Publicado 2010

Hypoestoxide reduces neuroinflammation and α-synuclein accumulation in a mouse model of Parkinson’s disease

por Kim, Changyoun, Ojo-Amaize, Emmanuel, Spencer, Brian, Rockenstein, Edward, Mante, Michael, Desplats, Paula, Wrasidlo, Wolf, Adame, Anthony, Nchekwube, Emeka, Oyemade, Olusola, Okogun, Joseph, Chan, Michael, Cottam, Howard, Masliah, Eliezer
Publicado 2015

Differential blood DNA methylation across Lewy body dementias

por Nasamran, Chanond A., Sachan, Anubhav Nikunj Singh, Mott, Jennifer, Kuras, Yuliya I., Scherzer, Clemens R., Study, Harvard Biomarkers, Ricciardelli, Eugenia, Jepsen, Kristen, Edland, Steven D., Fisch, Kathleen M., Desplats, Paula
Publicado 2021

Common Variants Near ZIC1 and ZIC4 in Autopsy-Confirmed Multiple System Atrophy

por Hopfner, Franziska, Tietz, Anja K., Ruf, Viktoria C., Ross, Owen A., Koga, Shunsuke, Dickson, Dennis, Aguzzi, Adriano, Attems, Johannes, Beach, Thomas, Beller, Allison, Cheshire, William P., van Deerlin, Vivianna, Desplats, Paula, Deuschl, Günther, Duyckaerts, Charles, Ellinghaus, David, Evsyukov, Valentin, Flanagan, Margaret Ellen, Franke, Andre, Frosch, Matthew P., Gearing, Marla, Gelpi, Ellen, van Gerpen, Jay A., Ghetti, Bernardino, Glass, Jonathan D., Grinberg, Lea T., Halliday, Glenda, Helbig, Ingo, Höllerhage, Matthias, Huitinga, Inge, Irwin, David John, Keene, Dirk C., Kovacs, Gabor G., Lee, Edward B., Levin, Johannes, Martí, Maria J., Mackenzie, Ian, McKeith, Ian, Mclean, Catriona, Mollenhauer, Brit, Neumann, Manuela, Newell, Kathy L., Pantelyat, Alex, Pendziwiat, Manuela, Peters, Annette, Porcel, Laura Molina, Rabano, Alberto, Matěj, Radoslav, Rajput, Alex, Rajput, Ali, Reimann, Regina, Scott, William K., Seeley, William, Selvackadunco, Sashika, Simuni, Tanya, Stadelmann, Christine, Svenningsson, Per, Thomas, Alan, Trenkwalder, Claudia, Troakes, Claire, Trojanowski, John Q., Uitti, Ryan J., White, Charles L., Wszolek, Zbigniew K., Xie, Tao, Ximelis, Teresa, Justo, Yebenes, Müller, Ulrich, Schellenberg, Gerard D., Herms, Jochen, Kuhlenbäumer, Gregor, Höglinger, Günter
Publicado 2022