Probenecid‐Boosted Tenofovir: A Physiologically‐Based Pharmacokinetic Model‐Informed Strategy for On‐Demand HIV Preexposure Prophylaxis

por Liu, Stephanie N., Desta, Zeruesenay, Gufford, Brandon T.
Publicado 2019

A Penalized Mixture Model Approach in Genotype/Phenotype Association Analysis for Quantitative Phenotypes

por Li, Lang, Borges, Silvana, Jason, Robarge D., Shen, Changyu, Desta, Zeruesenay, Flockhart, David
Publicado 2010

Efavirenz-mediated induction of omeprazole metabolism is CYP2C19 genotype-dependent

por Michaud, Veronique, Kreutz, Yvonne, Skaar, Todd, Ogburn, Evan, Thong, Nancy, Flockhart, David A., Desta, Zeruesenay
Publicado 2013

DrugMetab: An Integrated Machine Learning and Lexicon Mapping Named Entity Recognition Method for Drug Metabolite

por Wu, Heng‐Yi, Lu, Deshun, Hyder, Mustafa, Zhang, Shijun, Quinney, Sara K., Desta, Zeruesenay, Li, Lang
Publicado 2018

CYP2B6 Genotype‐Dependent Inhibition of CYP1A2 and Induction of CYP2A6 by the Antiretroviral Drug Efavirenz in Healthy Volunteers

por Metzger, Ingrid F., Dave, Nimita, Kreutz, Yvonne, Lu, Jessica B.L., Galinsky, Raymond E., Desta, Zeruesenay
Publicado 2019

Rifampin modulation of xeno‐ and endobiotic conjugating enzyme mRNA expression and associated microRNAs in human hepatocytes

por Gufford, Brandon T., Robarge, Jason D., Eadon, Michael T., Gao, Hongyu, Lin, Hai, Liu, Yunlong, Desta, Zeruesenay, Skaar, Todd C.
Publicado 2018

Rifampin Regulation of Drug Transporters Gene Expression and the Association of MicroRNAs in Human Hepatocytes

por Benson, Eric A., Eadon, Michael T., Desta, Zeruesenay, Liu, Yunlong, Lin, Hai, Burgess, Kimberly S., Segar, Matthew W., Gaedigk, Andrea, Skaar, Todd C.
Publicado 2016

Influence of paraoxonase-1 Q192R and cytochrome P450 2C19 polymorphisms on clopidogrel response

por Kreutz, Rolf P, Nystrom, Perry, Kreutz, Yvonne, Miao, Jia, Desta, Zeruesenay, Breall, Jeffrey A, Li, Lang, Chiang, ChienWei, Kovacs, Richard, Flockhart, David A, Jin, Yan
Publicado 2012

Clinically important alterations in pharmacogene expression in histologically severe nonalcoholic fatty liver disease

por Powell, Nicholas R., Liang, Tiebing, Ipe, Joseph, Cao, Sha, Skaar, Todd C., Desta, Zeruesenay, Qian, Hui-Rong, Ebert, Philip J., Chen, Yu, Thomas, Melissa K., Chalasani, Naga
Publicado 2023

Pentoxifylline, Inflammation, and Endothelial Function in HIV-Infected Persons: A Randomized, Placebo-Controlled Trial

por Gupta, Samir K., Mi, Deming, Dubé, Michael P., Saha, Chandan K., Johnson, Raymond M., Stein, James H., Clauss, Matthias A., Mather, Kieren J., Desta, Zeruesenay, Liu, Ziyue
Publicado 2013

Cytochrome P450 3A4*22, PPAR-α, and ARNT polymorphisms and clopidogrel response

por Kreutz, Rolf P, Owens, Janelle, Jin, Yan, Nystrom, Perry, Desta, Zeruesenay, Kreutz, Yvonne, Breall, Jeffrey A, Li, Lang, Chiang, ChienWei, Kovacs, Richard J, Flockhart, David A
Publicado 2013

Substantial Effect of Efavirenz Monotherapy on Bilirubin Levels in Healthy Volunteers

por Metzger, Ingrid F., Quigg, Troy C., Epstein, Noam, Aregbe, Abdulateef O., Thong, Nancy, Callaghan, John T., Flockhart, David A., Nguyen, Anne T., Stevens, Colleen K., Gupta, Samir K., Desta, Zeruesenay
Publicado 2014

Polymorphisms in drug-metabolizing enzymes and steady-state exemestane concentration in post-menopausal patients with breast cancer

por Hertz, Daniel L., Kidwell, Kelley M., Seewald, Nicholas J., Gersch, Christina L., Desta, Zeruesenay, Flockhart, David A, Storniolo, Ana-Maria, Stearns, Vered, Skaar, Todd C, Hayes, Daniel F, Henry, N. Lynn, Rae, James M.
Publicado 2016

Predicting neurodevelopmental risk in children born to mothers living with HIV in Kenya: protocol for a prospective cohort study (Tabiri Study)

por Oyungu, Eren, El Kebbi, Ola, Vreeman, Rachel, Nyandiko, Winstone, Monahan, Patrick O, Tu, Wanzhu, Khaitan, Alka, Desta, Zeruesenay, Slogrove, Amy L, Humphrey, John M, Were, Edwin, Patel, Rena C, Carlucci, James G, Wools-Kaloustian, Kara, McHenry, Megan S
Publicado 2022

Pharmacogenomics of selective serotonin reuptake inhibitor treatment for major depressive disorder: genome-wide associations and functional genomics

por Ji, Yuan, Biernacka, Joanna M., Hebbring, Scott, Chai, Yubo, Jenkins, Gregory D., Batzler, Anthony, Snyder, Karen A., Drews, Maureen S., Desta, Zeruesenay, Flockhart, David, Mushiroda, Taisei, Kubo, Michiaki, Nakamura, Yusuke, Kamatani, Naoyuki, Schaid, Daniel, Weinshilboum, Richard M., Mrazek, David A.
Publicado 2012

Genome-Wide Discovery of Drug-Dependent Human Liver Regulatory Elements

por Smith, Robin P., Eckalbar, Walter L., Morrissey, Kari M., Luizon, Marcelo R., Hoffmann, Thomas J., Sun, Xuefeng, Jones, Stacy L., Force Aldred, Shelley, Ramamoorthy, Anuradha, Desta, Zeruesenay, Liu, Yunlong, Skaar, Todd C., Trinklein, Nathan D., Giacomini, Kathleen M., Ahituv, Nadav
Publicado 2014

Anastrozole Aromatase Inhibitor Plasma Drug Concentration Genome‐Wide Association Study: Functional Epistatic Interaction Between SLC38A7 and ALPPL2

por Dudenkov, Tanda M., Liu, Duan, Cairns, Junmei, Devarajan, Sandhya, Zhuang, Yongxian, Ingle, James N., Buzdar, Aman U., Robson, Mark E., Kubo, Michiaki, Batzler, Anthony, Barman, Poulami, Jenkins, Gregory D., Carlson, Erin E., Goetz, Matthew P., Northfelt, Donald W., Moreno‐Aspitia, Alvaro, Desta, Zeruesenay, Reid, Joel M., Kalari, Krishna R., Wang, Liewei, Weinshilboum, Richard M.
Publicado 2019