Molecular Basis of Ligand Dissociation in β-Adrenergic Receptors

por González, Angel, Perez-Acle, Tomas, Pardo, Leonardo, Deupi, Xavier
Publicado 2011

TMalphaDB and TMbetaDB: web servers to study the structural role of sequence motifs in α-helix and β-barrel domains of membrane proteins

por Perea, Marc, Lugtenburg, Ivar, Mayol, Eduardo, Cordomí, Arnau, Deupí, Xavier, Pardo, Leonardo, Olivella, Mireia
Publicado 2015

The counterion–retinylidene Schiff base interaction of an invertebrate rhodopsin rearranges upon light activation

por Nagata, Takashi, Koyanagi, Mitsumasa, Tsukamoto, Hisao, Mutt, Eshita, Schertler, Gebhard F. X., Deupi, Xavier, Terakita, Akihisa
Publicado 2019

The DRF motif of CXCR6 as chemokine receptor adaptation to adhesion

por Koenen, Andrea, Babendreyer, Aaron, Schumacher, Julian, Pasqualon, Tobias, Schwarz, Nicole, Seifert, Anke, Deupi, Xavier, Ludwig, Andreas, Dreymueller, Daniela
Publicado 2017

The Two-Photon Reversible Reaction of the Bistable Jumping Spider Rhodopsin-1

por Ehrenberg, David, Varma, Niranjan, Deupi, Xavier, Koyanagi, Mitsumasa, Terakita, Akihisa, Schertler, Gebhard F.X., Heberle, Joachim, Lesca, Elena
Publicado 2019

GPCR-SAS: A web application for statistical analyses on G protein-coupled receptors sequences

por Gómez Tamayo, José Carlos, Olivella, Mireia, Ríos, Santiago, Hoogstraat, Marlous, Gonzalez, Angel, Mayol, Eduardo, Deupi, Xavier, Campillo, Mercedes, Cordomí, Arnau
Publicado 2018

Crystal structure of jumping spider rhodopsin-1 as a light sensitive GPCR

por Varma, Niranjan, Mutt, Eshita, Mühle, Jonas, Panneels, Valérie, Terakita, Akihisa, Deupi, Xavier, Nogly, Przemyslaw, Schertler, Gebhard F. X., Lesca, Elena
Publicado 2019

Batch crystallization of rhodopsin for structural dynamics using an X-ray free-electron laser

por Wu, Wenting, Nogly, Przemyslaw, Rheinberger, Jan, Kick, Leonhard M., Gati, Cornelius, Nelson, Garrett, Deupi, Xavier, Standfuss, Jörg, Schertler, Gebhard, Panneels, Valérie
Publicado 2015

β-arrestin1 and 2 exhibit distinct phosphorylation-dependent conformations when coupling to the same GPCR in living cells

por Haider, Raphael S., Matthees, Edda S. F., Drube, Julia, Reichel, Mona, Zabel, Ulrike, Inoue, Asuka, Chevigné, Andy, Krasel, Cornelius, Deupi, Xavier, Hoffmann, Carsten
Publicado 2022

Ligand-regulated oligomerization of β(2)-adrenoceptors in a model lipid bilayer

por Fung, Juan José, Deupi, Xavier, Pardo, Leonardo, Yao, Xiao Jie, Velez-Ruiz, Gisselle A, DeVree, Brian T, Sunahara, Roger K, Kobilka, Brian K
Publicado 2009

Convergent evolution of tertiary structure in rhodopsin visual proteins from vertebrates and box jellyfish

por Gerrard, Elliot, Mutt, Eshita, Nagata, Takashi, Koyanagi, Mitsumasa, Flock, Tilman, Lesca, Elena, Schertler, Gebhard F. X., Terakita, Akihisa, Deupi, Xavier, Lucas, Robert J.
Publicado 2018

Arrestin-1 engineering facilitates complex stabilization with native rhodopsin

por Haider, Raphael S., Wilhelm, Florian, Rizk, Aurélien, Mutt, Eshita, Deupi, Xavier, Peterhans, Christian, Mühle, Jonas, Berger, Philipp, Schertler, Gebhard F. X., Standfuss, Jörg, Ostermaier, Martin K.
Publicado 2019

Exploring the signaling space of a GPCR using bivalent ligands with a rigid oligoproline backbone

por Romantini, Nina, Alam, Shahidul, Dobitz, Stefanie, Spillmann, Martin, De Foresta, Martina, Schibli, Roger, Schertler, Gebhard F. X., Wennemers, Helma, Deupi, Xavier, Behe, Martin, Berger, Philipp
Publicado 2021

High-mass MALDI-MS unravels ligand-mediated G protein–coupling selectivity to GPCRs

por Wu, Na, Olechwier, Agnieszka M., Brunner, Cyrill, Edwards, Patricia C., Tsai, Ching-Ju, Tate, Christopher G., Schertler, Gebhard F. X., Schneider, Gisbert, Deupi, Xavier, Zenobi, Renato, Ma, Pikyee
Publicado 2021

Cryo-EM structure of the rhodopsin-Gαi-βγ complex reveals binding of the rhodopsin C-terminal tail to the gβ subunit

por Tsai, Ching-Ju, Marino, Jacopo, Adaixo, Ricardo, Pamula, Filip, Muehle, Jonas, Maeda, Shoji, Flock, Tilman, Taylor, Nicholas MI, Mohammed, Inayatulla, Matile, Hugues, Dawson, Roger JP, Deupi, Xavier, Stahlberg, Henning, Schertler, Gebhard
Publicado 2019

Structural Elements Directing G Proteins and β-Arrestin Interactions with the Human Melatonin Type 2 Receptor Revealed by Natural Variants

por Plouffe, Bianca, Karamitri, Angeliki, Flock, Tilman, Gallion, Jonathan M., Houston, Shane, Daly, Carole A., Bonnefond, Amélie, Guillaume, Jean-Luc, Le Gouill, Christian, Froguel, Phillipe, Lichtarge, Olivier, Deupi, Xavier, Jockers, Ralf, Bouvier, Michel
Publicado 2022

A tool for nuclear imaging of the SARS-CoV-2 entry receptor: molecular model and preclinical development of ACE2-selective radiopeptides

por Beyer, Darja, Vaccarin, Christian, Deupi, Xavier, Mapanao, Ana Katrina, Cohrs, Susan, Sozzi-Guo, Fan, Grundler, Pascal V., van der Meulen, Nicholas P., Wang, Jinling, Tanriver, Matthias, Bode, Jeffrey W., Schibli, Roger, Müller, Cristina
Publicado 2023

An experimental strategy to probe Gq contribution to signal transduction in living cells

por Patt, Julian, Alenfelder, Judith, Pfeil, Eva Marie, Voss, Jan Hendrik, Merten, Nicole, Eryilmaz, Funda, Heycke, Nina, Rick, Uli, Inoue, Asuka, Kehraus, Stefan, Deupi, Xavier, Müller, Christa E., König, Gabriele M., Crüsemann, Max, Kostenis, Evi
Publicado 2021

Crystal structure of rhodopsin in complex with a mini-G(o) sheds light on the principles of G protein selectivity

por Tsai, Ching-Ju, Pamula, Filip, Nehmé, Rony, Mühle, Jonas, Weinert, Tobias, Flock, Tilman, Nogly, Przemyslaw, Edwards, Patricia C., Carpenter, Byron, Gruhl, Thomas, Ma, Pikyee, Deupi, Xavier, Standfuss, Jörg, Tate, Christopher G., Schertler, Gebhard F. X.
Publicado 2018

Identification of Key Regions Mediating Human Melatonin Type 1 Receptor Functional Selectivity Revealed by Natural Variants

por Hegron, Alan, Huh, Eunna, Deupi, Xavier, Sokrat, Badr, Gao, Wenwen, Le Gouill, Christian, Canouil, Mickaël, Boissel, Mathilde, Charpentier, Guillaume, Roussel, Ronan, Balkau, Beverley, Froguel, Philippe, Plouffe, Bianca, Bonnefond, Amélie, Lichtarge, Olivier, Jockers, Ralf, Bouvier, Michel
Publicado 2021