A 3D-QSAR model for cannabinoid receptor (CB2) ligands derived from aligned pharmacophors

por Günther, Robert, Deuther-Conrad, Winnie, Moldovan, Rareś, Fischer, Steffen, Brust, Peter
Publicado 2013

Synthesis and Preliminary Biological Evaluation of Indol-3-yl-oxoacetamides as Potent Cannabinoid Receptor Type 2 Ligands

por Moldovan, Rareş-Petru, Deuther-Conrad, Winnie, Horti, Andrew G., Brust, Peter
Publicado 2017

Novel Radioligands for Cyclic Nucleotide Phosphodiesterase Imaging with Positron Emission Tomography: An Update on Developments Since 2012

por Schröder, Susann, Wenzel, Barbara, Deuther-Conrad, Winnie, Scheunemann, Matthias, Brust, Peter
Publicado 2016

Development of cannabinoid receptor (CB 2 R) ligands for application in PET studies - where to attach the radiolabel?

por Günther, Robert, Moldovan, Rareş, Lueg, Corinna, Deuther-Conrad, Winnie, Wünsch, Bernhard, Brust, Peter
Publicado 2014

Cannabinoid receptor type 2 (CB2)-selective N-aryl-oxadiazolyl-propionamides: synthesis, radiolabelling, molecular modelling and biological evaluation

por Rühl, Thomas, Deuther-Conrad, Winnie, Fischer, Steffen, Günther, Robert, Hennig, Lothar, Krautscheid, Harald, Brust, Peter
Publicado 2012

Selective α(3)β(4) Nicotinic Acetylcholine Receptor Ligand as a Potential Tracer for Drug Addiction

por Kanasuwan, Apinan, Deuther-Conrad, Winnie, Chongruchiroj, Sumet, Sarasamkan, Jiradanai, Chotipanich, Chanisa, Vajragupta, Opa, Arunrungvichian, Kuntarat
Publicado 2023

Development of [(18)F]LU14 for PET Imaging of Cannabinoid Receptor Type 2 in the Brain

por Teodoro, Rodrigo, Gündel, Daniel, Deuther-Conrad, Winnie, Ueberham, Lea, Toussaint, Magali, Bormans, Guy, Brust, Peter, Moldovan, Rareş-Petru
Publicado 2021

Radiosynthesis and Preclinical Evaluation of an (18)F-Labeled Triazolopyridopyrazine-Based Inhibitor for Neuroimaging of the Phosphodiesterase 2A (PDE2A)

por Wenzel, Barbara, Fritzsche, Stefan R., Toussaint, Magali, Briel, Detlef, Kopka, Klaus, Brust, Peter, Scheunemann, Matthias, Deuther-Conrad, Winnie
Publicado 2022

Radiosynthesis and Radiotracer Properties of a 7-(2-[(18)F]Fluoroethoxy)-6-methoxypyrrolidinylquinazoline for Imaging of Phosphodiesterase 10A with PET

por Funke, Uta, Deuther-Conrad, Winnie, Schwan, Gregor, Maisonial, Aurélie, Scheunemann, Matthias, Fischer, Steffen, Hiller, Achim, Briel, Detlef, Brust, Peter
Publicado 2012

Exploring the Metabolism of (+)-[(18)F]Flubatine In Vitro and In Vivo: LC-MS/MS Aided Identification of Radiometabolites in a Clinical PET Study †

por Ludwig, Friedrich-Alexander, Fischer, Steffen, Smits, René, Deuther-Conrad, Winnie, Hoepping, Alexander, Tiepolt, Solveig, Patt, Marianne, Sabri, Osama, Brust, Peter
Publicado 2018

Synthesis and Biological Evaluation of a Novel (18)F-Labeled Radiotracer for PET Imaging of the Adenosine A(2A) Receptor

por Lai, Thu Hang, Toussaint, Magali, Teodoro, Rodrigo, Dukić-Stefanović, Sladjana, Kranz, Mathias, Deuther-Conrad, Winnie, Moldovan, Rareş-Petru, Brust, Peter
Publicado 2021

Asymmetric Synthesis of Spirocyclic 2-Benzopyrans for Positron Emission Tomography of σ(1) Receptors in the Brain

por Holl, Katharina, Schepmann, Dirk, Fischer, Steffen, Ludwig, Friedrich-Alexander, Hiller, Achim, Donat, Cornelius K., Deuther-Conrad, Winnie, Brust, Peter, Wünsch, Bernhard
Publicado 2014

Synthesis, (18)F-Radiolabelling and Biological Characterization of Novel Fluoroalkylated Triazine Derivatives for in Vivo Imaging of Phosphodiesterase 2A in Brain via Positron Emis...

por Schröder, Susann, Wenzel, Barbara, Deuther-Conrad, Winnie, Teodoro, Rodrigo, Egerland, Ute, Kranz, Mathias, Scheunemann, Matthias, Höfgen, Norbert, Steinbach, Jörg, Brust, Peter
Publicado 2015

Discovery and development of brain-penetrant (18)F-labeled radioligands for neuroimaging of the sigma-2 receptors

por Zhang, Ying, Wang, Tao, Zhang, Xiaojun, Deuther-Conrad, Winnie, Fu, Hualong, Cui, Mengchao, Zhang, Jinming, Brust, Peter, Huang, Yiyun, Jia, Hongmei
Publicado 2022

Investigation of an (18)F-labelled Imidazopyridotriazine for Molecular Imaging of Cyclic Nucleotide Phosphodiesterase 2A

por Schröder, Susann, Wenzel, Barbara, Deuther-Conrad, Winnie, Teodoro, Rodrigo, Kranz, Mathias, Scheunemann, Matthias, Egerland, Ute, Höfgen, Norbert, Briel, Detlef, Steinbach, Jörg, Brust, Peter
Publicado 2018

Radiosynthesis and Biological Investigation of a Novel Fluorine-18 Labeled Benzoimidazotriazine-Based Radioligand for the Imaging of Phosphodiesterase 2A with Positron Emission Tom...

por Ritawidya, Rien, Wenzel, Barbara, Teodoro, Rodrigo, Toussaint, Magali, Kranz, Mathias, Deuther-Conrad, Winnie, Dukic-Stefanovic, Sladjana, Ludwig, Friedrich-Alexander, Scheunemann, Matthias, Brust, Peter
Publicado 2019

Synthesis of Novel Fluorinated Xanthine Derivatives with High Adenosine A(2B) Receptor Binding Affinity

por Lindemann, Marcel, Dukic-Stefanovic, Sladjana, Hinz, Sonja, Deuther-Conrad, Winnie, Teodoro, Rodrigo, Juhl, Cathleen, Steinbach, Jörg, Brust, Peter, Müller, Christa E., Wenzel, Barbara
Publicado 2021

Design, Radiosynthesis and Preliminary Biological Evaluation in Mice of a Brain-Penetrant (18)F-Labelled σ(2) Receptor Ligand

por Moldovan, Rareş-Petru, Gündel, Daniel, Teodoro, Rodrigo, Ludwig, Friedrich-Alexander, Fischer, Steffen, Toussaint, Magali, Schepmann, Dirk, Wünsch, Bernhard, Brust, Peter, Deuther-Conrad, Winnie
Publicado 2021

Radiofluorination and biological evaluation of N-aryl-oxadiazolyl-propionamides as potential radioligands for PET imaging of cannabinoid CB(2) receptors

por Teodoro, Rodrigo, Moldovan, Rareş-Petru, Lueg, Corinna, Günther, Robert, Donat, Cornelius K, Ludwig, Friedrich-Alexander, Fischer, Steffen, Deuther-Conrad, Winnie, Wünsch, Bernhard, Brust, Peter
Publicado 2013

Development of Fluorinated Non-Peptidic Ghrelin Receptor Ligands for Potential Use in Molecular Imaging

por Moldovan, Rareş-Petru, Els-Heindl, Sylvia, Worm, Dennis J., Kniess, Torsten, Kluge, Michael, Beck-Sickinger, Annette G., Deuther-Conrad, Winnie, Krügel, Ute, Brust, Peter
Publicado 2017