Considerations for the discovery and development of 3-chymotrypsin-like cysteine protease inhibitors targeting SARS-CoV-2 infection

por Vandyck, Koen, Deval, Jerome
Publicado 2021

Advances in antiviral nucleoside analogues and their prodrugs

por Seley-Radtke, Katherine, Deval, Jerome
Publicado 2018

Opportunities and Challenges in Targeting the Proofreading Activity of SARS-CoV-2 Polymerase Complex

por Deval, Jerome, Gurard-Levin, Zachary A.
Publicado 2022

Inhibition of viral RNA polymerases by nucleoside and nucleotide analogs: therapeutic applications against positive-strand RNA viruses beyond hepatitis C virus

por Deval, Jerome, Symons, Julian A, Beigelman, Leo
Publicado 2014

Innovation and trends in the development and approval of antiviral medicines: 1987–2017 and beyond

por Chaudhuri, Shuvam, Symons, Julian A., Deval, Jerome
Publicado 2018

Nucleosides for the treatment of respiratory RNA virus infections

por Jordan, Paul C, Stevens, Sarah K, Deval, Jerome
Publicado 2018

Characterization of the Elongation Complex of Dengue Virus RNA Polymerase: ASSEMBLY, KINETICS OF NUCLEOTIDE INCORPORATION, AND FIDELITY

por Jin, Zhinan, Deval, Jerome, Johnson, Kenneth A., Swinney, David C.
Publicado 2011

Structure(s), function(s), and inhibition of the RNA-dependent RNA polymerase of noroviruses

por Deval, Jerome, Jin, Zhinan, Chuang, Ying-Chih, Kao, C. Cheng
Publicado 2017

Label-Free Screening of SARS-CoV-2 NSP14 Exonuclease Activity Using SAMDI Mass Spectrometry

por Scholle, Michael D., Liu, Cheng, Deval, Jerome, Gurard-Levin, Zachary A.
Publicado 2021

Comparison of RNA synthesis initiation properties of non-segmented negative strand RNA virus polymerases

por Shareef, Afzaal M., Ludeke, Barbara, Jordan, Paul, Deval, Jerome, Fearns, Rachel
Publicado 2021

The Ambiguous Base-Pairing and High Substrate Efficiency of T-705 (Favipiravir) Ribofuranosyl 5′-Triphosphate towards Influenza A Virus Polymerase

por Jin, Zhinan, Smith, Lucas K., Rajwanshi, Vivek K., Kim, Baek, Deval, Jerome
Publicado 2013

Susceptibility of paramyxoviruses and filoviruses to inhibition by 2′-monofluoro- and 2′-difluoro-4′-azidocytidine analogs

por Lo, Michael K., Jordan, Paul C., Stevens, Sarah, Tam, Yuen, Deval, Jerome, Nichol, Stuart T., Spiropoulou, Christina F.
Publicado 2018

Subgenomic promoter recognition by the norovirus RNA-dependent RNA polymerases

por Lin, Xiaoyan, Thorne, Lucy, Jin, Zhinan, Hammad, Loubna A., Li, Serena, Deval, Jerome, Goodfellow, Ian G., Kao, C. Cheng
Publicado 2015

Initiation, extension, and termination of RNA synthesis by a paramyxovirus polymerase

por Jordan, Paul C., Liu, Cheng, Raynaud, Pauline, Lo, Michael K., Spiropoulou, Christina F., Symons, Julian A., Beigelman, Leo, Deval, Jerome
Publicado 2018

Biochemical Effect of Resistance Mutations against Synergistic Inhibitors of RSV RNA Polymerase

por Deval, Jerome, Fung, Amy, Stevens, Sarah K., Jordan, Paul C., Gromova, Tatiana, Taylor, Joshua S., Hong, Jin, Meng, Jia, Wang, Guangyi, Dyatkina, Natalia, Prhavc, Marija, Symons, Julian A., Beigelman, Leo
Publicado 2016

Dual inhibition of SARS-CoV-2 and human rhinovirus with protease inhibitors in clinical development

por Liu, Cheng, Boland, Sandro, Scholle, Michael D., Bardiot, Dorothee, Marchand, Arnaud, Chaltin, Patrick, Blatt, Lawrence M., Beigelman, Leonid, Symons, Julian A., Raboisson, Pierre, Gurard-Levin, Zachary A., Vandyck, Koen, Deval, Jerome
Publicado 2021

Evaluation of SARS-CoV-2 3C-like protease inhibitors using self-assembled monolayer desorption ionization mass spectrometry

por Gurard-Levin, Zachary A., Liu, Cheng, Jekle, Andreas, Jaisinghani, Ruchika, Ren, Suping, Vandyck, Koen, Jochmans, Dirk, Leyssen, Pieter, Neyts, Johan, Blatt, Lawrence M., Beigelman, Leonid, Symons, Julian A., Raboisson, Pierre, Scholle, Michael D., Deval, Jerome
Publicado 2020

Regulation of gene transcription by thyroid hormone receptor β agonists in clinical development for the treatment of non-alcoholic steatohepatitis (NASH)

por Luong, Xuan G., Stevens, Sarah K., Jekle, Andreas, Lin, Tse-I, Gupta, Kusum, Misner, Dinah, Chanda, Sushmita, Mukherjee, Sucheta, Williams, Caroline, Stoycheva, Antitsa, Blatt, Lawrence M., Beigelman, Leonid N., Symons, Julian A., Raboisson, Pierre, McGowan, David, Vandyck, Koen, Deval, Jerome
Publicado 2020

Tumor Regression upon Intratumoral and Subcutaneous Dosing of the STING Agonist ALG-031048 in Mouse Efficacy Models

por Jekle, Andreas, Thatikonda, Santosh Kumar, Jaisinghani, Ruchika, Ren, Suping, Kinkade, April, Stevens, Sarah K., Stoycheva, Antitsa, Rajwanshi, Vivek K., Williams, Caroline, Deval, Jerome, Mukherjee, Sucheta, Zhang, Qingling, Chanda, Sushmita, Smith, David B., Blatt, Lawrence M., Symons, Julian A., Gonzalvez, Francois, Beigelman, Leonid
Publicado 2023

Meeting report: 34th international conference on antiviral research

por Brancale, Andrea, Carter, Kara, Delang, Leen, Deval, Jerome, Durantel, David, Gentry, Brian G, Jordan, Robert, Julander, Justin G., Lo, Michael K., Pérez-Pérez, Maria-Jesús, Schang, Luis M., Seley-Radtke, Katherine L., Shi, Pei-Yong, Vasudevan, Subhash G., Whitley, Richard J., Spengler, Jessica R.
Publicado 2022