RIG-I recognizes metabolite-capped RNAs as signaling ligands

por Schweibenz, Brandon D, Solotchi, Mihai, Hanpude, Pranita, Devarkar, Swapnil C, Patel, Smita S
Publicado 2023

Sarecycline inhibits protein translation in Cutibacterium acnes 70S ribosome using a two-site mechanism

por Lomakin, Ivan B, Devarkar, Swapnil C, Patel, Shivali, Grada, Ayman, Bunick, Christopher G
Publicado 2023

Structures of a Mobile Intron Retroelement Poised to Attack Its Structured DNA Target

por Chung, Kevin, Xu, Ling, Chai, Pengxin, Peng, Junhui, Devarkar, Swapnil C., Pyle, Anna Marie
Publicado 2022

The autoinhibitory CARD2-Hel2i Interface of RIG-I governs RNA selection

por Ramanathan, Anand, Devarkar, Swapnil C., Jiang, Fuguo, Miller, Matthew T., Khan, Abdul G., Marcotrigiano, Joseph, Patel, Smita S.
Publicado 2016

Nodal modulator (NOMO) is required to sustain endoplasmic reticulum morphology

por Amaya, Catherine, Cameron, Christopher J.F., Devarkar, Swapnil C., Seager, Sebastian J.H., Gerstein, Mark B., Xiong, Yong, Schlieker, Christian
Publicado 2021

The intrinsically disordered CARDs‐Helicase linker in RIG‐I is a molecular gate for RNA proofreading

por Schweibenz, Brandon D, Devarkar, Swapnil C, Solotchi, Mihai, Craig, Candice, Zheng, Jie, Pascal, Bruce D, Gokhale, Samantha, Xie, Ping, Griffin, Patrick R, Patel, Smita S
Publicado 2022

Nonstructural Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity Factor Redirecting Host Protein Synthesis Machinery toward Viral RNA

por Yuan, Shuai, Peng, Lei, Park, Jonathan J., Hu, Yingxia, Devarkar, Swapnil C., Dong, Matthew B., Shen, Qi, Wu, Shenping, Chen, Sidi, Lomakin, Ivan B., Xiong, Yong
Publicado 2020

HDX-MS reveals dysregulated checkpoints that compromise discrimination against self RNA during RIG-I mediated autoimmunity

por Zheng, Jie, Wang, Chen, Chang, Mi Ra, Devarkar, Swapnil C., Schweibenz, Brandon, Crynen, Gogce C., Garcia-Ordonez, Ruben D., Pascal, Bruce D., Novick, Scott J., Patel, Smita S., Marcotrigiano, Joseph, Griffin, Patrick R.
Publicado 2018

The capsid lattice engages a bipartite NUP153 motif to mediate nuclear entry of HIV-1 cores

por Shen, Qi, Kumari, Sushila, Xu, Chaoyi, Jang, Sooin, Shi, Jiong, Burdick, Ryan C., Levintov, Lev, Xiong, Qiancheng, Wu, Chunxiang, Devarkar, Swapnil C., Tian, Taoran, Tripler, Therese N., Hu, Yingxia, Yuan, Shuai, Temple, Joshua, Feng, Qingzhou, Lusk, C. Patrick, Aiken, Christopher, Engelman, Alan N., Perilla, Juan R., Pathak, Vinay K., Lin, Chenxiang, Xiong, Yong
Publicado 2023