A novel aptamer-based small RNA delivery platform and its application to cancer therapy

por Tanno, Toshihiko, Zhang, Peng, Bailey, Christopher, Wang, Yin, Ittiprasert, Wannaporn, Devenport, Martin, Zheng, Pan, Liu, Yang
Publicado 2022

Targeting HIF-1α abrogates PD-L1–mediated immune evasion in tumor microenvironment but promotes tolerance in normal tissues

por Bailey, Christopher M., Liu, Yan, Liu, Mingyue, Du, Xuexiang, Devenport, Martin, Zheng, Pan, Liu, Yang, Wang, Yin
Publicado 2022

Structure of CTLA-4 complexed with a pH-sensitive cancer immunotherapeutic antibody

por Gao, Han, Cai, Haiyan, Liu, Jia, Wang, Xiaoxiao, Zheng, Pan, Devenport, Martin, Xu, Ting, Dou, Fei, Liu, Yang, Zhou, Aiwu
Publicado 2020

CD24Fc ameliorates immune-related adverse events while preserving anti-tumor therapeutic effect

por Liu, Mingyue, Wang, Xu, Du, Xuexiang, Zhang, Yan, Ai, Chunxia, Hu-Lieskovan, Siwen, Li, Tianhong, Devenport, Martin, Liu, Yang, Zheng, Pan
Publicado 2022

Uncoupling therapeutic from immunotherapy-related adverse effects for safer and effective anti-CTLA-4 antibodies in CTLA4 humanized mice

por Du, Xuexiang, Liu, Mingyue, Su, Juanjuan, Zhang, Peng, Tang, Fei, Ye, Peiying, Devenport, Martin, Wang, Xu, Zhang, Yan, Liu, Yang, Zheng, Pan
Publicado 2018

Mechanism- and Immune Landscape-Based Ranking of Therapeutic Responsiveness of 22 Major Human Cancers to Next Generation Anti-CTLA-4 Antibodies

por Zhang, Peng, Xiong, Xinxin, Rolfo, Christian, Du, Xuexiang, Zhang, Yan, Yang, Han, Russo, Alessandro, Devenport, Martin, Zhou, Penghui, Liu, Yang, Zheng, Pan
Publicado 2020

Malaria Parasite Invasion of the Mosquito Salivary Gland Requires Interaction between the Plasmodium TRAP and the Anopheles Saglin Proteins

por Ghosh, Anil K., Devenport, Martin, Jethwaney, Deepa, Kalume, Dario E., Pandey, Akhilesh, Anderson, Vernon E., Sultan, Ali A., Kumar, Nirbhay, Jacobs-Lorena, Marcelo
Publicado 2009

Hijacking antibody-induced CTLA-4 lysosomal degradation for safer and more effective cancer immunotherapy

por Zhang, Yan, Du, Xuexiang, Liu, Mingyue, Tang, Fei, Zhang, Peng, Ai, Chunxia, Fields, James K., Sundberg, Eric J., Latinovic, Olga S., Devenport, Martin, Zheng, Pan, Liu, Yang
Publicado 2019

A reappraisal of CTLA-4 checkpoint blockade in cancer immunotherapy

por Du, Xuexiang, Tang, Fei, Liu, Mingyue, Su, Juanjuan, Zhang, Yan, Wu, Wei, Devenport, Martin, Lazarski, Christopher A, Zhang, Peng, Wang, Xu, Ye, Peiying, Wang, Changyu, Hwang, Eugene, Zhu, Tinghui, Xu, Ting, Zheng, Pan, Liu, Yang
Publicado 2018

Efficacy and safety of CD24Fc in hospitalised patients with COVID-19: a randomised, double-blind, placebo-controlled, phase 3 study

por Welker, James, Pulido, Juan D, Catanzaro, Andrew T, Malvestutto, Carlos D, Li, Zihai, Cohen, Jonathan B, Whitman, Eric D, Byrne, Dana, Giddings, Olivia K, Lake, Jordan E, Chua, Joel V, Li, Ella, Chen, Jian, Zhou, Xiang, He, Kun, Gates, Davis, Kaur, Amarjot, Chen, Jamie, Chou, Hung-Yen, Devenport, Martin, Touomou, Raymond, Kottilil, Shyamasundaran, Liu, Yang, Zheng, Pan
Publicado 2022

TREATMENT WITH SOLUBLE CD24 ATTENUATES COVID-19-ASSOCIATED SYSTEMIC IMMUNOPATHOLOGY

por Song, No-Joon, Allen, Carter, Vilgelm, Anna E., Riesenberg, Brian P., Weller, Kevin P., Reynolds, Kelsi, Chakravarthy, Karthik B., Kumar, Amrendra, Khatiwada, Aastha, Sun, Zequn, Ma, Anjun, Chang, Yuzhou, Yusuf, Mohamed, Li, Anqi, Zeng, Cong, Evans, John P., Bucci, Donna, Gunasena, Manuja, Xu, Menglin, Liyanage, Namal P.M., Bolyard, Chelsea, Velegraki, Maria, Liu, Shan-Lu, Ma, Qin, Devenport, Martin, Liu, Yang, Zheng, Pan, Malvestutto, Carlos D., Chung, Dongjun, Li, Zihai
Publicado 2021

Treatment with soluble CD24 attenuates COVID-19-associated systemic immunopathology

por Song, No-Joon, Allen, Carter, Vilgelm, Anna E., Riesenberg, Brian P., Weller, Kevin P., Reynolds, Kelsi, Chakravarthy, Karthik B., Kumar, Amrendra, Khatiwada, Aastha, Sun, Zequn, Ma, Anjun, Chang, Yuzhou, Yusuf, Mohamed, Li, Anqi, Zeng, Cong, Evans, John P., Bucci, Donna, Gunasena, Manuja, Xu, Menglin, Liyanage, Namal P. M., Bolyard, Chelsea, Velegraki, Maria, Liu, Shan-Lu, Ma, Qin, Devenport, Martin, Liu, Yang, Zheng, Pan, Malvestutto, Carlos D., Chung, Dongjun, Li, Zihai
Publicado 2022