A biosynthetic pathway for a prominent class of microbiota-derived bile acids

por Devlin, A. Sloan, Fischbach, Michael A.
Publicado 2015

A selective gut bacterial bile salt hydrolase alters host metabolism

por Yao, Lina, Seaton, Sarah Craven, Ndousse-Fetter, Sula, Adhikari, Arijit A, DiBenedetto, Nicholas, Mina, Amir I, Banks, Alexander S, Bry, Lynn, Devlin, A Sloan
Publicado 2018

Bariatric surgery reveals a gut-restricted TGR5 agonist with anti-diabetic effects

por Chaudhari, Snehal N., Harris, David A., Aliakbarian, Hassan, Luo, James N., Henke, Matthew T., Subramaniam, Renuka, Vernon, Ashley H., Tavakkoli, Ali, Sheu, Eric G., Devlin, A. Sloan
Publicado 2020

Inhibition of microbial deconjugation of micellar bile acids protects against intestinal permeability and liver injury

por Li, Darrick K., Chaudhari, Snehal N., Lee, Yoojin, Sojoodi, Mozhdeh, Adhikari, Arijit A., Zukerberg, Lawrence, Shroff, Stuti, Barrett, Stephen Cole, Tanabe, Kenneth, Chung, Raymond T., Devlin, A. Sloan
Publicado 2022

Development of a Covalent Inhibitor of Gut Bacterial Bile Salt Hydrolases

por Adhikari, Arijit A., Seegar, Tom C. M., Ficarro, Scott B., McCurry, Megan D., Ramachandran, Deepti, Yao, Lina, Chaudhari, Snehal N., Ndousse-Fetter, Sula, Banks, Alexander S., Marto, Jarrod A., Blacklow, Stephen C., Devlin, A. Sloan
Publicado 2020

Diet rapidly and reproducibly alters the human gut microbiome

por David, Lawrence A., Maurice, Corinne F., Carmody, Rachel N., Gootenberg, David B., Button, Julie E., Wolfe, Benjamin E., Ling, Alisha V., Devlin, A. Sloan, Varma, Yug, Fischbach, Michael A., Biddinger, Sudha B., Dutton, Rachel J., Turnbaugh, Peter J.
Publicado 2013

Bile acid metabolites control Th17 and Treg cell differentiation

por Hang, Saiyu, Paik, Donggi, Yao, Lina, Kim, Eunha, Jamma, Trinath, Lu, Jingping, Ha, Soyoung, Nelson, Brandon N., Kelly, Samantha P., Wu, Lin, Zheng, Ye, Longman, Randy S., Rastinejad, Fraydoon, Devlin, A. Sloan, Krout, Michael R., Fischbach, Michael A., Littman, Dan R., Huh, Jun R.
Publicado 2019