Novel Type V-A CRISPR Effectors Are Active Nucleases with Expanded Targeting Capabilities

por Aliaga Goltsman, Daniela S., Alexander, Lisa M., Devoto, Audra E., Albers, Justine B., Liu, Jason, Butterfield, Cristina N., Brown, Christopher T., Thomas, Brian C.
Publicado 2020

Megaphages infect Prevotella and variants are widespread in gut microbiomes

por Devoto, Audra E., Santini, Joanne M., Olm, Matthew R., Anantharaman, Karthik, Munk, Patrick, Tung, Jenny, Archie, Elizabeth A., Turnbaugh, Peter J., Seed, Kimberley D., Blekhman, Ran, Aarestrup, Frank M., Thomas, Brian C., Banfield, Jillian F.
Publicado 2019

Novel CRISPR-Associated Gene-Editing Systems Discovered in Metagenomic Samples Enable Efficient and Specific Genome Engineering

por Lamothe, Rebecca C., Storlie, Meghan D., Espinosa, Diego A., Rudlaff, Rachel, Browne, Patrick, Liu, Jason, Rivas, Andres, Devoto, Audra, Oki, Jennifer, Khoubyari, Ashcon, Goltsman, Daniela S. Aliaga, Lin, Jyun-Liang, Butterfield, Cristina N., Brown, Christopher T., Thomas, Brian C., Cost, Gregory J.
Publicado 2023

Compact Cas9d and HEARO enzymes for genome editing discovered from uncultivated microbes

por Aliaga Goltsman, Daniela S., Alexander, Lisa M., Lin, Jyun-Liang, Fregoso Ocampo, Rodrigo, Freeman, Benjamin, Lamothe, Rebecca C., Perez Rivas, Andres, Temoche-Diaz, Morayma M., Chadha, Shailaja, Nordenfelt, Natalie, Janson, Owen P., Barr, Ian, Devoto, Audra E., Cost, Gregory J., Butterfield, Cristina N., Thomas, Brian C., Brown, Christopher T.
Publicado 2022

Closely related Lak megaphages replicate in the microbiomes of diverse animals

por Crisci, Marco A., Chen, Lin-Xing, Devoto, Audra E., Borges, Adair L., Bordin, Nicola, Sachdeva, Rohan, Tett, Adrian, Sharrar, Allison M., Segata, Nicola, Debenedetti, Francesco, Bailey, Mick, Burt, Rachel, Wood, Rhiannon M., Rowden, Lewis J., Corsini, Paula M., van Winden, Steven, Holmes, Mark A., Lei, Shufei, Banfield, Jillian F., Santini, Joanne M.
Publicado 2021

Novel and Engineered Type II CRISPR Systems from Uncultivated Microbes with Broad Genome Editing Capability

por Alexander, Lisa M., Aliaga Goltsman, Daniela S., Liu, Jason, Lin, Jyun-Liang, Temoche-Diaz, Morayma M., Laperriere, Sarah M., Neerincx, Andreas, Bednarski, Christien, Knyphausen, Philipp, Cohnen, Andre, Albers, Justine, Gonzalez-Osorio, Liliana, Fregoso Ocampo, Rodrigo, Oki, Jennifer, Devoto, Audra E., Castelle, Cindy J., Lamothe, Rebecca C., Cost, Gregory J., Butterfield, Cristina N., Thomas, Brian C., Brown, Christopher T.
Publicado 2023

Clades of huge phages from across Earth’s ecosystems

por Al-Shayeb, Basem, Sachdeva, Rohan, Chen, Lin-Xing, Ward, Fred, Munk, Patrick, Devoto, Audra, Castelle, Cindy J., Olm, Matthew R., Bouma-Gregson, Keith, Amano, Yuki, He, Christine, Méheust, Raphaël, Brooks, Brandon, Thomas, Alex, Lavy, Adi, Matheus-Carnevali, Paula, Sun, Christine, Goltsman, Daniela S. A., Borton, Mikayla A., Sharrar, Allison, Jaffe, Alexander L., Nelson, Tara C., Kantor, Rose, Keren, Ray, Lane, Katherine R., Farag, Ibrahim F., Lei, Shufei, Finstad, Kari, Amundson, Ronald, Anantharaman, Karthik, Zhou, Jinglie, Probst, Alexander J., Power, Mary E., Tringe, Susannah G., Li, Wen-Jun, Wrighton, Kelly, Harrison, Sue, Morowitz, Michael, Relman, David A., Doudna, Jennifer A., Lehours, Anne-Catherine, Warren, Lesley, Cate, Jamie H. D., Santini, Joanne M., Banfield, Jillian F.
Publicado 2020