No Time to Relax and Unwind: Exploration of Topoisomerases and a Growing Field of Study

por Deweese, Joseph E., Osheroff, Neil
Publicado 2023

The DNA cleavage reaction of topoisomerase II: wolf in sheep's clothing

por Deweese, Joseph E., Osheroff, Neil
Publicado 2009

Human topoisomerase IIα uses a two-metal-ion mechanism for DNA cleavage

por Deweese, Joseph E., Burgin, Alex B., Osheroff, Neil
Publicado 2008

Cannabidiol oxidation product HU-331 is a potential anticancer cannabinoid-quinone: a narrative review

por Trac, Judy, Keck, J. Myles, Deweese, Joseph E.
Publicado 2021

A novel and unified two-metal mechanism for DNA cleavage by type II and IA topoisomerases

por Schmidt, Bryan H., Burgin, Alex B., Deweese, Joseph E., Osheroff, Neil, Berger, James M.
Publicado 2010

Inhibition of Topoisomerases by Metal Thiosemicarbazone Complexes

por Jiang, Xiaohua, Fielding, Lauren A., Davis, Hunter, Carroll, William, Lisic, Edward C., Deweese, Joseph E.
Publicado 2023

Etoposide Quinone Is a Covalent Poison of Human Topoisomerase IIβ

por Smith, Nicholas A., Byl, Jo Ann W., Mercer, Susan L., Deweese, Joseph E., Osheroff, Neil
Publicado 2014

Examining the Impact of Antimicrobial Fluoroquinolones on Human DNA Topoisomerase IIα and IIβ

por Fief, Cole A., Hoang, Kristine G., Phipps, Stephen D., Wallace, Jessica L., Deweese, Joseph E.
Publicado 2019

Catalytic Core of Human Topoisomerase IIα: Insights into Enzyme–DNA Interactions and Drug Mechanism

por Lindsey, R. Hunter, Pendleton, MaryJean, Ashley, Rachel E., Mercer, Susan L., Deweese, Joseph E., Osheroff, Neil
Publicado 2014

Exploration of the Role of the C-Terminal Domain of Human DNA Topoisomerase IIα in Catalytic Activity

por Dougherty, Ashley C., Hawaz, Mariam G., Hoang, Kristine G., Trac, Judy, Keck, Jacob M., Ayes, Carmen, Deweese, Joseph E.
Publicado 2021

PSICalc: a novel approach to identifying and ranking critical non-proximal interdependencies within the overall protein structure

por Townsley, Thomas D, Wilson, James T, Akers, Harrison, Bryant, Timothy, Cordova, Salvador, Wallace, T L, Durston, Kirk K, Deweese, Joseph E
Publicado 2022