Two roads to death – Bax targets mitochondria by distinct routes before or during apoptotic cell death

por Dewson, Grant
Publicado 2015

Mitochondria and apoptosis: emerging concepts

por Li, Mark Xiang, Dewson, Grant
Publicado 2015

Therapeutic targeting of mitophagy in Parkinson's disease

por Masaldan, Shashank, Callegari, Sylvie, Dewson, Grant
Publicado 2022

Multigene family isoform profiling from blood cell lineages

por Dewson, Grant, Conley, Edward C, Bradding, Peter
Publicado 2002

Ubiquitin signalling in neurodegeneration: mechanisms and therapeutic opportunities

por Schmidt, Marlene F., Gan, Zhong Yan, Komander, David, Dewson, Grant
Publicado 2021

A new crystal form of GABARAPL2

por Scicluna, Kristen, Dewson, Grant, Czabotar, Peter E., Birkinshaw, Richard W.
Publicado 2021

VDAC2 and the BCL-2 family of proteins

por Yuan, Zheng, Dewson, Grant, Czabotar, Peter E., Birkinshaw, Richard W.
Publicado 2021

Translocation of a Bak C-Terminus Mutant from Cytosol to Mitochondria to Mediate Cytochrome c Release: Implications for Bak and Bax Apoptotic Function

por Ferrer, Pedro Eitz, Frederick, Paul, Gulbis, Jacqueline M., Dewson, Grant, Kluck, Ruth M.
Publicado 2012

Mitochondrial permeabilization relies on BH3 ligands engaging multiple prosurvival Bcl-2 relatives, not Bak

por Uren, Rachel T., Dewson, Grant, Chen, Lin, Coyne, Stephanie C., Huang, David C.S., Adams, Jerry M., Kluck, Ruth M.
Publicado 2007

Robust autoactivation for apoptosis by BAK but not BAX highlights BAK as an important therapeutic target

por Iyer, Sweta, Uren, Rachel T., Dengler, Michael A., Shi, Melissa X., Uno, Etsuko, Adams, Jerry M., Dewson, Grant, Kluck, Ruth M.
Publicado 2020

Disordered clusters of Bak dimers rupture mitochondria during apoptosis

por Uren, Rachel T, O’Hely, Martin, Iyer, Sweta, Bartolo, Ray, Shi, Melissa X, Brouwer, Jason M, Alsop, Amber E, Dewson, Grant, Kluck, Ruth M
Publicado 2017

Identification of an activation site in Bak and mitochondrial Bax triggered by antibodies

por Iyer, Sweta, Anwari, Khatira, Alsop, Amber E., Yuen, Wai Shan, Huang, David C. S., Carroll, John, Smith, Nicholas A., Smith, Brian J., Dewson, Grant, Kluck, Ruth M.
Publicado 2016

Activation mechanism of PINK1

por Gan, Zhong Yan, Callegari, Sylvie, Cobbold, Simon A., Cotton, Thomas R., Mlodzianoski, Michael J., Schubert, Alexander F., Geoghegan, Niall D., Rogers, Kelly L., Leis, Andrew, Dewson, Grant, Glukhova, Alisa, Komander, David
Publicado 2021

Publisher Correction: Activation mechanism of PINK1

por Gan, Zhong Yan, Callegari, Sylvie, Cobbold, Simon A., Cotton, Thomas R., Mlodzianoski, Michael J., Schubert, Alexander F., Geoghegan, Niall D., Rogers, Kelly L., Leis, Andrew, Dewson, Grant, Glukhova, Alisa, Komander, David
Publicado 2022

Mutant TRP53 exerts a target gene-selective dominant-negative effect to drive tumor development

por Aubrey, Brandon J., Janic, Ana, Chen, Yunshun, Chang, Catherine, Lieschke, Elizabeth C., Diepstraten, Sarah T., Kueh, Andrew J., Bernardini, Jonathan P., Dewson, Grant, O'Reilly, Lorraine A., Whitehead, Lachlan, Voss, Anne K., Smyth, Gordon K., Strasser, Andreas, Kelly, Gemma L.
Publicado 2018

Mesenchymal stromal cell apoptosis is required for their therapeutic function

por Pang, Swee Heng Milon, D’Rozario, Joshua, Mendonca, Senora, Bhuvan, Tejasvini, Payne, Natalie L., Zheng, Di, Hisana, Assifa, Wallis, Georgia, Barugahare, Adele, Powell, David, Rautela, Jai, Huntington, Nicholas D., Dewson, Grant, Huang, David C. S., Gray, Daniel H. D., Heng, Tracy S. P.
Publicado 2021

Physiological restraint of Bak by Bcl-x(L) is essential for cell survival

por Lee, Erinna F., Grabow, Stephanie, Chappaz, Stephane, Dewson, Grant, Hockings, Colin, Kluck, Ruth M., Debrincat, Marlyse A., Gray, Daniel H., Witkowski, Matthew T., Evangelista, Marco, Pettikiriarachchi, Anne, Bouillet, Philippe, Lane, Rachael M., Czabotar, Peter E., Colman, Peter M., Smith, Brian J., Kile, Benjamin T., Fairlie, W. Douglas
Publicado 2016

An aspartyl protease defines a novel pathway for export of Toxoplasma proteins into the host cell

por Coffey, Michael J, Sleebs, Brad E, Uboldi, Alessandro D, Garnham, Alexandra, Franco, Magdalena, Marino, Nicole D, Panas, Michael W, Ferguson, David JP, Enciso, Marta, O'Neill, Matthew T, Lopaticki, Sash, Stewart, Rebecca J, Dewson, Grant, Smyth, Gordon K, Smith, Brian J, Masters, Seth L, Boothroyd, John C, Boddey, Justin A, Tonkin, Christopher J
Publicado 2015

VDAC2 enables BAX to mediate apoptosis and limit tumor development

por Chin, Hui San, Li, Mark X., Tan, Iris K. L., Ninnis, Robert L., Reljic, Boris, Scicluna, Kristen, Dagley, Laura F., Sandow, Jarrod J., Kelly, Gemma L., Samson, Andre L., Chappaz, Stephane, Khaw, Seong L., Chang, Catherine, Morokoff, Andrew, Brinkmann, Kerstin, Webb, Andrew, Hockings, Colin, Hall, Cathrine M., Kueh, Andrew J., Ryan, Michael T., Kluck, Ruth M., Bouillet, Philippe, Herold, Marco J., Gray, Daniel H. D., Huang, David C. S., van Delft, Mark F., Dewson, Grant
Publicado 2018

Mechanism and inhibition of the papain‐like protease, PLpro, of SARS‐CoV‐2

por Klemm, Theresa, Ebert, Gregor, Calleja, Dale J, Allison, Cody C, Richardson, Lachlan W, Bernardini, Jonathan P, Lu, Bernadine GC, Kuchel, Nathan W, Grohmann, Christoph, Shibata, Yuri, Gan, Zhong Yan, Cooney, James P, Doerflinger, Marcel, Au, Amanda E, Blackmore, Timothy R, van der Heden van Noort, Gerbrand J, Geurink, Paul P, Ovaa, Huib, Newman, Janet, Riboldi‐Tunnicliffe, Alan, Czabotar, Peter E, Mitchell, Jeffrey P, Feltham, Rebecca, Lechtenberg, Bernhard C, Lowes, Kym N, Dewson, Grant, Pellegrini, Marc, Lessene, Guillaume, Komander, David
Publicado 2020