Structural Lessons From the Mutant Proinsulin Syndrome

por Dhayalan, Balamurugan, Chatterjee, Deepak, Chen, Yen-Shan, Weiss, Michael A.
Publicado 2021

Structural principles of insulin formulation and analog design: A century of innovation

por Jarosinski, Mark A., Dhayalan, Balamurugan, Chen, Yen-Shan, Chatterjee, Deepak, Varas, Nicolás, Weiss, Michael A.
Publicado 2021

Distinct states of proinsulin misfolding in MIDY

por Haataja, Leena, Arunagiri, Anoop, Hassan, Anis, Regan, Kaitlin, Tsai, Billy, Dhayalan, Balamurugan, Weiss, Michael A., Liu, Ming, Arvan, Peter
Publicado 2021

Peptide Model of the Mutant Proinsulin Syndrome. II. Nascent Structure and Biological Implications

por Yang, Yanwu, Glidden, Michael D., Dhayalan, Balamurugan, Zaykov, Alexander N., Chen, Yen-Shan, Wickramasinghe, Nalinda P., DiMarchi, Richard D., Weiss, Michael A.
Publicado 2022

Peptide Model of the Mutant Proinsulin Syndrome. I. Design and Clinical Correlation

por Dhayalan, Balamurugan, Glidden, Michael D., Zaykov, Alexander N., Chen, Yen-Shan, Yang, Yanwu, Phillips, Nelson B., Ismail-Beigi, Faramarz, Jarosinski, Mark A., DiMarchi, Richard D., Weiss, Michael A.
Publicado 2022

Insertion of a Synthetic Switch Into Insulin Provides Metabolite-Dependent Regulation of Hormone-Receptor Activation

por Chen, Yen-Shan, Gleaton, Jeremy, Yang, Yanwu, Dhayalan, Balamurugan, Phillips, Nelson B, Liu, Yule, Broadwater, Laurie, Jarosinski, Mark, Chatterjee, Deepak, Lawrence, Michael C, Hattier, Thomas, Michael, Dodson M, Weiss, Michael Aaron
Publicado 2021