Mevalonate metabolism–dependent protein geranylgeranylation regulates thymocyte egress

por Du, Xingrong, Zeng, Hu, Liu, Shaofeng, Guy, Cliff, Dhungana, Yogesh, Neale, Geoffrey, Bergo, Martin O., Chi, Hongbo
Publicado 2019

Truncated HSPB1 causes axonal neuropathy and impairs tolerance to unfolded protein stress

por Ylikallio, Emil, Konovalova, Svetlana, Dhungana, Yogesh, Hilander, Taru, Junna, Nella, Partanen, Juhani V., Toppila, Jussi P., Auranen, Mari, Tyynismaa, Henna
Publicado 2015

Hippo/Mst signaling coordinates cellular quiescence with terminal maturation in iNKT cell development and fate decisions

por Raynor, Jana L., Liu, Chaohong, Dhungana, Yogesh, Guy, Cliff, Chapman, Nicole M., Shi, Hao, Neale, Geoffrey, Sesaki, Hiromi, Chi, Hongbo
Publicado 2020

Critical roles of mTORC1 signaling and metabolic reprogramming for M-CSF–mediated myelopoiesis

por Karmaus, Peer W.F., Herrada, Andrés A., Guy, Cliff, Neale, Geoffrey, Dhungana, Yogesh, Long, Lingyun, Vogel, Peter, Avila, Julian, Clish, Clary B., Chi, Hongbo
Publicado 2017

mTOR coordinates transcriptional programs and mitochondrial metabolism of activated T(reg) subsets to protect tissue homeostasis

por Chapman, Nicole M., Zeng, Hu, Nguyen, Thanh-Long M., Wang, Yanyan, Vogel, Peter, Dhungana, Yogesh, Liu, Xiaojing, Neale, Geoffrey, Locasale, Jason W., Chi, Hongbo
Publicado 2018

Discrete roles and bifurcation of PTEN signaling and mTORC1-mediated anabolic metabolism underlie IL-7–driven B lymphopoiesis

por Zeng, Hu, Yu, Mei, Tan, Haiyan, Li, Yuxin, Su, Wei, Shi, Hao, Dhungana, Yogesh, Guy, Cliff, Neale, Geoffrey, Cloer, Caryn, Peng, Junmin, Wang, Demin, Chi, Hongbo
Publicado 2018

Lipid signalling enforces T(reg) cell functional specialization in tumours

por Lim, Seon Ah, Wei, Jun, Nguyen, Thanh-Long M., Shi, Hao, Su, Wei, Palacios, Gustavo, Dhungana, Yogesh, Chapman, Nicole M., Long, Lingyun, Saravia, Jordy, Vogel, Peter, Chi, Hongbo
Publicado 2021

SLC38A2 and glutamine signalling in cDC1s dictate anti-tumour immunity

por Guo, Chuansheng, You, Zhiyuan, Shi, Hao, Sun, Yu, Du, Xingrong, Palacios, Gustavo, Guy, Cliff, Yuan, Sujing, Chapman, Nicole M., Lim, Seon Ah, Sun, Xiang, Saravia, Jordy, Rankin, Sherri, Dhungana, Yogesh, Chi, Hongbo
Publicado 2023

Homeostasis and transitional activation of regulatory T cells require c-Myc

por Saravia, Jordy, Zeng, Hu, Dhungana, Yogesh, Bastardo Blanco, Daniel, Nguyen, Thanh-Long M., Chapman, Nicole M., Wang, Yanyan, Kanneganti, Apurva, Liu, Shaofeng, Raynor, Jana L., Vogel, Peter, Neale, Geoffrey, Carmeliet, Peter, Chi, Hongbo
Publicado 2020

Targeting Regnase-1 programs long-lived effector T cells for cancer therapy

por Wei, Jun, Long, Lingyun, Zheng, Wenting, Dhungana, Yogesh, Lim, Seon Ah, Guy, Cliff, Wang, Yanyan, Wang, Yong-Dong, Qian, Chenxi, Xu, Beisi, Anil, KC, Saravia, Jordy, Huang, Hongling, Yu, Jiyang, Doench, John G., Geiger, Terrence L., Chi, Hongbo
Publicado 2019

scMINER: a mutual information-based framework for identifying hidden drivers from single-cell omics data

por Ding, Liang, Shi, Hao, Qian, Chenxi, Burdyshaw, Chad, Veloso, Joao Pedro, Khatamian, Alireza, Pan, Qingfei, Dhungana, Yogesh, Xie, Zhen, Risch, Isabel, Yang, Xu, Huang, Xin, Yan, Lei, Rusch, Michael, Brewer, Michael, Yan, Koon-Kiu, Chi, Hongbo, Yu, Jiyang
Publicado 2023

scMINER: a mutual information-based framework for identifying hidden drivers from single-cell omics data

por Ding, Liang, Shi, Hao, Qian, Chenxi, Burdyshaw, Chad, Veloso, Joao Pedro, Khatamian, Alireza, Pan, Qingfei, Dhungana, Yogesh, Xie, Zhen, Risch, Isabel, Yang, Xu, Huang, Xin, Yan, Lei, Rusch, Michael, Brewer, Michael, Yan, Koon-Kiu, Chi, Hongbo, Yu, Jiyang
Publicado 2023

NetBID2 provides comprehensive hidden driver analysis

por Dong, Xinran, Ding, Liang, Thrasher, Andrew, Wang, Xinge, Liu, Jingjing, Pan, Qingfei, Rash, Jordan, Dhungana, Yogesh, Yang, Xu, Risch, Isabel, Li, Yuxin, Yan, Lei, Rusch, Michael, McLeod, Clay, Yan, Koon-Kiu, Peng, Junmin, Chi, Hongbo, Zhang, Jinghui, Yu, Jiyang
Publicado 2023

Metabolic heterogeneity underlies reciprocal fates of T(H)17 cell stemness and plasticity

por Karmaus, Peer W F, Chen, Xiang, Lim, Seon Ah, Herrada, Andrés A, Nguyen, Thanh-Long M, Xu, Beisi, Dhungana, Yogesh, Rankin, Sherri, Chen, Wenan, Rosencrance, Celeste, Yang, Kai, Fan, Yiping, Cheng, Yong, Easton, John, Neale, Geoffrey, Vogel, Peter, Chi, Hongbo
Publicado 2018

Integrome signatures of lentiviral gene therapy for SCID-X1 patients

por Yan, Koon-Kiu, Condori, Jose, Ma, Zhijun, Metais, Jean-Yves, Ju, Bensheng, Ding, Liang, Dhungana, Yogesh, Palmer, Lance E., Langfitt, Deanna M., Ferrara, Francesca, Throm, Robert, Shi, Hao, Risch, Isabel, Bhatara, Sheetal, Shaner, Bridget, Lockey, Timothy D., Talleur, Aimee C., Easton, John, Meagher, Michael M., Puck, Jennifer M., Cowan, Morton J., Zhou, Sheng, Mamcarz, Ewelina, Gottschalk, Stephen, Yu, Jiyang
Publicado 2023

Inhibition of mitochondrial complex I reverses NOTCH1-driven metabolic reprogramming in T-cell acute lymphoblastic leukemia

por Baran, Natalia, Lodi, Alessia, Dhungana, Yogesh, Herbrich, Shelley, Collins, Meghan, Sweeney, Shannon, Pandey, Renu, Skwarska, Anna, Patel, Shraddha, Tremblay, Mathieu, Kuruvilla, Vinitha Mary, Cavazos, Antonio, Kaplan, Mecit, Warmoes, Marc O., Veiga, Diogo Troggian, Furudate, Ken, Rojas-Sutterin, Shanti, Haman, Andre, Gareau, Yves, Marinier, Anne, Ma, Helen, Harutyunyan, Karine, Daher, May, Garcia, Luciana Melo, Al-Atrash, Gheath, Piya, Sujan, Ruvolo, Vivian, Yang, Wentao, Shanmugavelandy, Sriram Saravanan, Feng, Ningping, Gay, Jason, Du, Di, Yang, Jun J., Hoff, Fieke W., Kaminski, Marcin, Tomczak, Katarzyna, Eric Davis, R., Herranz, Daniel, Ferrando, Adolfo, Jabbour, Elias J., Emilia Di Francesco, M., Teachey, David T., Horton, Terzah M., Kornblau, Steven, Rezvani, Katayoun, Sauvageau, Guy, Gagea, Mihai, Andreeff, Michael, Takahashi, Koichi, Marszalek, Joseph R., Lorenzi, Philip L., Yu, Jiyang, Tiziani, Stefano, Hoang, Trang, Konopleva, Marina
Publicado 2022