Ex vivo gene modification therapy for genetic skin diseases—recent advances in gene modification technologies and delivery

por Jayarajan, Vignesh, Kounatidou, Evangelia, Qasim, Waseem, Di, Wei‐Li
Publicado 2021

Tissue Kallikrein Inhibitors Based on the Sunflower Trypsin Inhibitor Scaffold – A Potential Therapeutic Intervention for Skin Diseases

por Chen, Wenjie, Kinsler, Veronica A., Macmillan, Derek, Di, Wei-Li
Publicado 2016

Short-Term Treatment with Rho-Associated Kinase Inhibitor Preserves Keratinocyte Stem Cell Characteristics In Vitro

por Jayarajan, Vignesh, Hall, George T., Xenakis, Theodoros, Bulstrode, Neil, Moulding, Dale, Castellano, Sergi, Di, Wei-Li
Publicado 2023

Efficient CRISPR-Cas9-Mediated Gene Ablation in Human Keratinocytes to Recapitulate Genodermatoses: Modeling of Netherton Syndrome

por Gálvez, Victoria, Chacón-Solano, Esteban, Bonafont, Jose, Mencía, Ángeles, Di, Wei-Li, Murillas, Rodolfo, Llames, Sara, Vicente, Asunción, Del Rio, Marcela, Carretero, Marta, Larcher, Fernando
Publicado 2020

Cytosine Deaminase Base Editing to Restore COL7A1 in Dystrophic Epidermolysis Bullosa Human: Murine Skin Model

por Naso, Gaetano, Gkazi, Soragia Athina, Georgiadis, Christos, Jayarajan, Vignesh, Jacków, Joanna, Fleck, Roland, Allison, Leanne, Ogunbiyi, Olumide Kayode, McGrath, John Alexander, Ilic, Dusko, Di, Wei-Li, Petrova, Anastasia, Qasim, Waseem
Publicado 2023

Molecular Genetic Dissection of Inflammatory Linear Verrucous Epidermal Naevus Leads to Successful Targeted Therapy

por Riachi, Melissa, Polubothu, Satyamaanasa, Stadnik, Paulina, Hughes, Connor, Martin, Sara Barberan, Charman, Carolyn R., Cheng, Iek Leng, Gholam, Karolina, Ogunbiyi, Olumide, Paige, David G., Sebire, Neil J., Pittman, Alan, Di, Wei-Li, Kinsler, Veronica A.
Publicado 2021

A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a...

por Naeem, Aishath S., Tommasi, Cristina, Cole, Christian, Brown, Stuart J., Zhu, Yanan, Way, Benjamin, Willis Owen, Saffron A.G., Moffatt, Miriam, Cookson, William O., Harper, John I., Di, Wei-Li, Brown, Sara J., Reinheckel, Thomas, O'Shaughnessy, Ryan F.L.
Publicado 2017

Lentiviral Engineered Fibroblasts Expressing Codon-Optimized COL7A1 Restore Anchoring Fibrils in RDEB

por Georgiadis, Christos, Syed, Farhatullah, Petrova, Anastasia, Abdul-Wahab, Alya, Lwin, Su M., Farzaneh, Farzin, Chan, Lucas, Ghani, Sumera, Fleck, Roland A., Glover, Leanne, McMillan, James R., Chen, Mei, Thrasher, Adrian J., McGrath, John A., Di, Wei-Li, Qasim, Waseem
Publicado 2016

Inherited duplications of PPP2R3B predispose to nevi and melanoma via a C21orf91-driven proliferative phenotype

por Polubothu, Satyamaanasa, Zecchin, Davide, Al-Olabi, Lara, Lionarons, Daniël A., Harland, Mark, Horswell, Stuart, Thomas, Anna C., Hunt, Lilian, Wlodarchak, Nathan, Aguilera, Paula, Brand, Sarah, Bryant, Dale, Carrera, Cristina, Chen, Hui, Elgar, Greg, Harwood, Catherine A., Howell, Michael, Larue, Lionel, Loughlin, Sam, MacDonald, Jeff, Malvehy, Josep, Barberan, Sara Martin, da Silva, Vanessa Martins, Molina, Miriam, Morrogh, Deborah, Moulding, Dale, Nsengimana, Jérémie, Pittman, Alan, Puig-Butillé, Joan-Anton, Parmar, Kiran, Sebire, Neil J., Scherer, Stephen, Stadnik, Paulina, Stanier, Philip, Tell, Gemma, Waelchli, Regula, Zarrei, Mehdi, Puig, Susana, Bataille, Véronique, Xing, Yongna, Healy, Eugene, Moore, Gudrun E., Di, Wei-Li, Newton-Bishop, Julia, Downward, Julian, Kinsler, Veronica A.
Publicado 2021