Mechanisms of ligand binding

por Di Cera, Enrico
Publicado 2020

Role of sequence and position of the cleavage sites in prothrombin activation

por Stojanovski, Bosko M., Di Cera, Enrico
Publicado 2021

Comparative sequence analysis of vitamin K‐dependent coagulation factors

por Stojanovski, Bosko M., Di Cera, Enrico
Publicado 2022

Probing prothrombin structure by limited proteolysis

por Acquasaliente, Laura, Pelc, Leslie A., Di Cera, Enrico
Publicado 2019

Role of the activation peptide in the mechanism of protein C activation

por Stojanovski, Bosko M., Pelc, Leslie A., Di Cera, Enrico
Publicado 2020

Interplay between conformational selection and zymogen activation

por Chakraborty, Pradipta, Acquasaliente, Laura, Pelc, Leslie A., Di Cera, Enrico
Publicado 2018

Zymogen and activated protein C have similar structural architecture

por Stojanovski, Bosko M., Pelc, Leslie A., Zuo, Xiaobing, Di Cera, Enrico
Publicado 2020

Cryo-EM structure of coagulation factor V short

por Mohammed, Bassem M., Pelc, Leslie A., Rau, Michael J., Di Cera, Enrico
Publicado 2023

Cryo‐EM structures of coagulation factors

por Di Cera, Enrico, Mohammed, Bassem M., Pelc, Leslie A., Stojanovski, Bosko M.
Publicado 2022

Structural Basis of Sequential and Concerted Cooperativity

por Morea, Veronica, Angelucci, Francesco, Tame, Jeremy R. H., Di Cera, Enrico, Bellelli, Andrea
Publicado 2022

Rational Design of Protein C Activators

por Barranco-Medina, Sergio, Murphy, Mary, Pelc, Leslie, Chen, Zhiwei, Di Cera, Enrico, Pozzi, Nicola
Publicado 2017

Residues W215, E217 and E192 control the allosteric E*-E equilibrium of thrombin

por Pelc, Leslie A., Koester, Sarah K., Chen, Zhiwei, Gistover, Noah E., Di Cera, Enrico
Publicado 2019

Role of the I16-D194 ionic interaction in the trypsin fold

por Stojanovski, Bosko M., Chen, Zhiwei, Koester, Sarah K., Pelc, Leslie A., Di Cera, Enrico
Publicado 2019

The active site region plays a critical role in Na(+) binding to thrombin

por Pelc, Leslie A., Koester, Sarah K., Kukla, Cassandra R., Chen, Zhiwei, Di Cera, Enrico
Publicado 2021

Cryo-EM structure of the prothrombin-prothrombinase complex

por Ruben, Eliza A., Summers, Brock, Rau, Michael J., Fitzpatrick, James A. J., Di Cera, Enrico
Publicado 2022

Structure of prothrombin in the closed form reveals new details on the mechanism of activation

por Chinnaraj, Mathivanan, Chen, Zhiwei, Pelc, Leslie A., Grese, Zachary, Bystranowska, Dominika, Di Cera, Enrico, Pozzi, Nicola
Publicado 2018

(19)F NMR reveals the conformational properties of free thrombin and its zymogen precursor prethrombin-2

por Ruben, Eliza A., Gandhi, Prafull S., Chen, Zhiwei, Koester, Sarah K., DeKoster, Gregory T., Frieden, Carl, Di Cera, Enrico
Publicado 2020

Thrombin Cleavage of Plasmodium falciparum Erythrocyte Membrane Protein 1 Inhibits Cytoadherence

por Gillrie, Mark R., Renaux, Bernard, Russell-Goldman, Eleanor, Avril, Marion, Brazier, Andrew J., Mihara, Koichiro, Di Cera, Enrico, Milner, Danny A., Hollenberg, Morley D., Smith, Joseph D., Ho, May
Publicado 2016

Costimulatory Effects of an Immunodominant Parasite Antigen Paradoxically Prevent Induction of Optimal CD8 T Cell Protective Immunity

por Eickhoff, Christopher S., Zhang, Xiuli, Vasconcelos, Jose R., Motz, R. Geoffrey, Sullivan, Nicole L., O’Shea, Kelly, Pozzi, Nicola, Gohara, David W., Blase, Jennifer R., Di Cera, Enrico, Hoft, Daniel F.
Publicado 2016

Reversible covalent direct thrombin inhibitors

por Sivaraja, Mohanram, Pozzi, Nicola, Rienzo, Matthew, Lin, Kenneth, Shiau, Timothy P., Clemens, Daniel M., Igoudin, Lev, Zalicki, Piotr, Chang, Stephanie S., Estiarte, M. Angels, Short, Kevin M., Williams, David C., Datta, Anirban, Di Cera, Enrico, Kita, David B.
Publicado 2018