Long‐lasting pathological consequences of overexpression‐induced α‐synuclein spreading in the rat brain

por Rusconi, Raffaella, Ulusoy, Ayse, Aboutalebi, Helia, Di Monte, Donato A.
Publicado 2018

Overexpression-Induced α-Synuclein Brain Spreading

por Pinto-Costa, Rita, Harbachova, Eugenia, La Vitola, Pietro, Di Monte, Donato A.
Publicado 2022

Neuron-to-neuron α-synuclein propagation in vivo is independent of neuronal injury

por Ulusoy, Ayse, Musgrove, Ruth E, Rusconi, Raffaella, Klinkenberg, Michael, Helwig, Michael, Schneider, Anja, Di Monte, Donato A
Publicado 2015

Sphingolipid changes in Parkinson L444P GBA mutation fibroblasts promote α-synuclein aggregation

por Galvagnion, Céline, Marlet, Frederik Ravnkilde, Cerri, Silvia, Schapira, Anthony H V, Blandini, Fabio, Di Monte, Donato A
Publicado 2022

Interneuronal In Vivo Transfer of Synaptic Proteins

por Klinkenberg, Michael, Helwig, Michael, Pinto-Costa, Rita, Rollar, Angela, Rusconi, Raffaella, Di Monte, Donato A., Ulusoy, Ayse
Publicado 2023

Inhibition of microglial β-glucocerebrosidase hampers the microglia-mediated antioxidant and protective response in neurons

por Brunialti, Electra, Villa, Alessandro, Mekhaeil, Marianna, Mornata, Federica, Vegeto, Elisabetta, Maggi, Adriana, Di Monte, Donato A., Ciana, Paolo
Publicado 2021

α-Synuclein Suppression by Targeted Small Interfering RNA in the Primate Substantia Nigra

por McCormack, Alison L., Mak, Sally K., Henderson, Jaimie M., Bumcrot, David, Farrer, Matthew J., Di Monte, Donato A.
Publicado 2010

The L444P Gba1 mutation enhances alpha-synuclein induced loss of nigral dopaminergic neurons in mice

por Migdalska-Richards, Anna, Wegrzynowicz, Michal, Rusconi, Raffaella, Deangeli, Giulio, Di Monte, Donato A, Spillantini, Maria G, Schapira, Anthony H V
Publicado 2017

GBA Mutations Influence the Release and Pathological Effects of Small Extracellular Vesicles from Fibroblasts of Patients with Parkinson’s Disease

por Cerri, Silvia, Ghezzi, Cristina, Ongari, Gerardo, Croce, Stefania, Avenali, Micol, Zangaglia, Roberta, Di Monte, Donato A., Valente, Enza Maria, Blandini, Fabio
Publicado 2021

MAO-B Elevation in Mouse Brain Astrocytes Results in Parkinson's Pathology

por Mallajosyula, Jyothi K., Kaur, Deepinder, Chinta, Shankar J., Rajagopalan, Subramanian, Rane, Anand, Nicholls, David G., Di Monte, Donato A., Macarthur, Heather, Andersen, Julie K.
Publicado 2008

Correction: MAO-B Elevation in Mouse Brain Astrocytes Results in Parkinson's Pathology

por Mallajosyula, Jyothi K., Kaur, Deepinder, Chinta, Shankar J., Rajagopalan, Subramanian, Rane, Anand, Nicholls, David G., Di Monte, Donato A., Macarthur, Heather, Andersen, Julie K.
Publicado 2012

Activation of the DNA damage response in vivo in synucleinopathy models of Parkinson’s disease

por Milanese, Chiara, Cerri, Silvia, Ulusoy, Ayse, Gornati, Simona V., Plat, Audrey, Gabriels, Sylvia, Blandini, Fabio, Di Monte, Donato A., Hoeijmakers, Jan H., Mastroberardino, Pier G.
Publicado 2018

Neuronal hyperactivity–induced oxidant stress promotes in vivo α-synuclein brain spreading

por Helwig, Michael, Ulusoy, Ayse, Rollar, Angela, O’Sullivan, Sinead A., Lee, Shirley S. L., Aboutalebi, Helia, Pinto-Costa, Rita, Jevans, Benjamin, Klinkenberg, Michael, Di Monte, Donato A.
Publicado 2022

Gender biased neuroprotective effect of Transferrin Receptor 2 deletion in multiple models of Parkinson’s disease

por Milanese, Chiara, Gabriels, Sylvia, Barnhoorn, Sander, Cerri, Silvia, Ulusoy, Ayse, Gornati, S. V., Wallace, Daniel F., Blandini, Fabio, Di Monte, Donato A., Subramaniam, V. Nathan, Mastroberardino, Pier G.
Publicado 2020

LRRK2 kinase regulates α-synuclein propagation via RAB35 phosphorylation

por Bae, Eun-Jin, Kim, Dong-Kyu, Kim, Changyoun, Mante, Michael, Adame, Anthony, Rockenstein, Edward, Ulusoy, Ayse, Klinkenberg, Michael, Jeong, Ga Ram, Bae, Jae Ryul, Lee, Cheolsoon, Lee, He-Jin, Lee, Byung-Dae, Di Monte, Donato A., Masliah, Eliezer, Lee, Seung-Jae
Publicado 2018

Inflammation promotes synucleinopathy propagation

por Kim, Tae-Kyung, Bae, Eun-Jin, Jung, Byung Chul, Choi, Minsun, Shin, Soo Jean, Park, Sung Jun, Kim, Jeong Tae, Jung, Min Kyo, Ulusoy, Ayse, Song, Mi-Young, Lee, Jun Sung, Lee, He-Jin, Di Monte, Donato A., Lee, Seung-Jae
Publicado 2022

Serine 129 Phosphorylation Reduces the Ability of α-Synuclein to Regulate Tyrosine Hydroxylase and Protein Phosphatase 2A in Vitro and in Vivo

por Lou, Haiyan, Montoya, Susana E., Alerte, Tshianda N. M., Wang, Jian, Wu, Jianjun, Peng, Xiangmin, Hong, Chang-Sook, Friedrich, Emily E., Mader, Samantha A., Pedersen, Courtney J., Marcus, Brian S., McCormack, Alison L., Di Monte, Donato A., Daubner, S. Colette, Perez, Ruth G.
Publicado 2010

Phosphorylation of Parkin at serine 65 is essential for its activation in vivo

por McWilliams, Thomas G., Barini, Erica, Pohjolan-Pirhonen, Risto, Brooks, Simon P., Singh, François, Burel, Sophie, Balk, Kristin, Kumar, Atul, Montava-Garriga, Lambert, Prescott, Alan R., Hassoun, Sidi Mohamed, Mouton-Liger, François, Ball, Graeme, Hills, Rachel, Knebel, Axel, Ulusoy, Ayse, Di Monte, Donato A., Tamjar, Jevgenia, Antico, Odetta, Fears, Kyle, Smith, Laura, Brambilla, Riccardo, Palin, Eino, Valori, Miko, Eerola-Rautio, Johanna, Tienari, Pentti, Corti, Olga, Dunnett, Stephen B., Ganley, Ian G., Suomalainen, Anu, Muqit, Miratul M. K.
Publicado 2018