Human spermatogonial stem cells and their niche in male (in)fertility: novel concepts from single-cell RNA-sequencing

por Di Persio, Sara, Neuhaus, Nina
Publicado 2022

The sperm epigenome does not display recurrent epimutations in patients with severely impaired spermatogenesis

por Leitão, Elsa, Di Persio, Sara, Laurentino, Sandra, Wöste, Marius, Dugas, Martin, Kliesch, Sabine, Neuhaus, Nina, Horsthemke, Bernhard
Publicado 2020

Effect of Mitotane on Male Gonadal Function

por Innocenti, Federica, Di Persio, Sara, Taggi, Marilena, Maggio, Roberta, Lardo, Pina, Toscano, Vincenzo, Canipari, Rita, Vicini, Elena, Stigliano, Antonio
Publicado 2023

An Orchestrated Intron Retention Program in Meiosis Controls Timely Usage of Transcripts during Germ Cell Differentiation

por Naro, Chiara, Jolly, Ariane, Di Persio, Sara, Bielli, Pamela, Setterblad, Niclas, Alberdi, Antonio J., Vicini, Elena, Geremia, Raffaele, De la Grange, Pierre, Sette, Claudio
Publicado 2017

High-resolution analysis of germ cells from men with sex chromosomal aneuploidies reveals normal transcriptome but impaired imprinting

por Laurentino, Sandra, Heckmann, Laura, Di Persio, Sara, Li, Xiaolin, Meyer zu Hörste, Gerd, Wistuba, Joachim, Cremers, Jann-Frederik, Gromoll, Jörg, Kliesch, Sabine, Schlatt, Stefan, Neuhaus, Nina
Publicado 2019

Whole-genome methylation analysis of testicular germ cells from cryptozoospermic men points to recurrent and functionally relevant DNA methylation changes

por Di Persio, Sara, Leitão, Elsa, Wöste, Marius, Tekath, Tobias, Cremers, Jann-Frederik, Dugas, Martin, Li, Xiaolin, zu Hörste, Gerd Meyer, Kliesch, Sabine, Laurentino, Sandra, Neuhaus, Nina, Horsthemke, Bernhard
Publicado 2021

DDX3Y is likely the key spermatogenic factor in the AZFa region that contributes to human non-obstructive azoospermia

por Dicke, Ann-Kristin, Pilatz, Adrian, Wyrwoll, Margot J., Punab, Margus, Ruckert, Christian, Nagirnaja, Liina, Aston, Kenneth I., Conrad, Donald F., Di Persio, Sara, Neuhaus, Nina, Fietz, Daniela, Laan, Maris, Stallmeyer, Birgit, Tüttelmann, Frank
Publicado 2023

TRIM71 Deficiency Causes Germ Cell Loss During Mouse Embryogenesis and Is Associated With Human Male Infertility

por Torres-Fernández, Lucia A., Emich, Jana, Port, Yasmine, Mitschka, Sibylle, Wöste, Marius, Schneider, Simon, Fietz, Daniela, Oud, Manon S., Di Persio, Sara, Neuhaus, Nina, Kliesch, Sabine, Hölzel, Michael, Schorle, Hubert, Friedrich, Corinna, Tüttelmann, Frank, Kolanus, Waldemar
Publicado 2021

Transcriptome analyses in infertile men reveal germ cell–specific expression and splicing patterns

por Siebert-Kuss, Lara M, Krenz, Henrike, Tekath, Tobias, Wöste, Marius, Di Persio, Sara, Terwort, Nicole, Wyrwoll, Margot J, Cremers, Jann-Frederik, Wistuba, Joachim, Dugas, Martin, Kliesch, Sabine, Schlatt, Stefan, Tüttelmann, Frank, Gromoll, Jörg, Neuhaus, Nina, Laurentino, Sandra
Publicado 2022

Single-cell RNA-seq unravels alterations of the human spermatogonial stem cell compartment in patients with impaired spermatogenesis

por Di Persio, Sara, Tekath, Tobias, Siebert-Kuss, Lara Marie, Cremers, Jann-Frederik, Wistuba, Joachim, Li, Xiaolin, Meyer zu Hörste, Gerd, Drexler, Hannes C.A., Wyrwoll, Margot Julia, Tüttelmann, Frank, Dugas, Martin, Kliesch, Sabine, Schlatt, Stefan, Laurentino, Sandra, Neuhaus, Nina
Publicado 2021