Crystal structure of the ternary complex of Leishmania major pteridine reductase 1 with the cofactor NADP(+)/NADPH and the substrate folic acid

por Dello Iacono, Lucia, Di Pisa, Flavio, Mangani, Stefano
Publicado 2022

Release of Soybean Isoflavones by Using a β‐Glucosidase from Alicyclobacillus herbarius

por Delgado, Lidia, Heckmann, Christian M., Di Pisa, Flavio, Gourlay, Louise, Paradisi, Francesca
Publicado 2020

Two novel fish paralogs provide insights into the Rid family of imine deaminases active in pre-empting enamine/imine metabolic damage

por Digiovanni, Stefania, Visentin, Cristina, Degani, Genny, Barbiroli, Alberto, Chiara, Matteo, Regazzoni, Luca, Di Pisa, Flavio, Borchert, Andrew J., Downs, Diana M., Ricagno, Stefano, Vanoni, Maria Antonietta, Popolo, Laura
Publicado 2020

Structure, Immunoreactivity, and In Silico Epitope Determination of SmSPI S. mansoni Serpin for Immunodiagnostic Application

por De Benedetti, Stefano, Di Pisa, Flavio, Fassi, Enrico Mario Alessandro, Cretich, Marina, Musicò, Angelo, Frigerio, Roberto, Mussida, Alessandro, Bombaci, Mauro, Grifantini, Renata, Colombo, Giorgio, Bolognesi, Martino, Grande, Romualdo, Zanchetta, Nadia, Gismondo, Maria Rita, Mileto, Davide, Mancon, Alessandro, Gourlay, Louise Jane
Publicado 2021

Elucidating the 3D Structure of a Surface Membrane Antigen from Trypanosoma cruzi as a Serodiagnostic Biomarker of Chagas Disease

por Di Pisa, Flavio, De Benedetti, Stefano, Fassi, Enrico Mario Alessandro, Bombaci, Mauro, Grifantini, Renata, Musicò, Angelo, Frigerio, Roberto, Pontillo, Angela, Rigo, Cinzia, Abelli, Sandra, Grande, Romualdo, Zanchetta, Nadia, Mileto, Davide, Mancon, Alessandro, Rizzo, Alberto, Gori, Alessandro, Cretich, Marina, Colombo, Giorgio, Bolognesi, Martino, Gourlay, Louise Jane
Publicado 2022

Multitarget, Selective Compound Design Yields Potent Inhibitors of a Kinetoplastid Pteridine Reductase 1

por Pöhner, Ina, Quotadamo, Antonio, Panecka-Hofman, Joanna, Luciani, Rosaria, Santucci, Matteo, Linciano, Pasquale, Landi, Giacomo, Di Pisa, Flavio, Dello Iacono, Lucia, Pozzi, Cecilia, Mangani, Stefano, Gul, Sheraz, Witt, Gesa, Ellinger, Bernhard, Kuzikov, Maria, Santarem, Nuno, Cordeiro-da-Silva, Anabela, Costi, Maria P., Venturelli, Alberto, Wade, Rebecca C.
Publicado 2022

Chroman-4-One Derivatives Targeting Pteridine Reductase 1 and Showing Anti-Parasitic Activity

por Di Pisa, Flavio, Landi, Giacomo, Dello Iacono, Lucia, Pozzi, Cecilia, Borsari, Chiara, Ferrari, Stefania, Santucci, Matteo, Santarem, Nuno, Cordeiro-da-Silva, Anabela, Moraes, Carolina B., Alcantara, Laura M., Fontana, Vanessa, Freitas-Junior, Lucio H., Gul, Sheraz, Kuzikov, Maria, Behrens, Birte, Pöhner, Ina, Wade, Rebecca C., Costi, Maria Paola, Mangani, Stefano
Publicado 2017

Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery

por Linciano, Pasquale, Dawson, Alice, Pöhner, Ina, Costa, David M., Sá, Monica S., Cordeiro-da-Silva, Anabela, Luciani, Rosaria, Gul, Sheraz, Witt, Gesa, Ellinger, Bernhard, Kuzikov, Maria, Gribbon, Philip, Reinshagen, Jeanette, Wolf, Markus, Behrens, Birte, Hannaert, Véronique, Michels, Paul A. M., Nerini, Erika, Pozzi, Cecilia, di Pisa, Flavio, Landi, Giacomo, Santarem, Nuno, Ferrari, Stefania, Saxena, Puneet, Lazzari, Sandra, Cannazza, Giuseppe, Freitas-Junior, Lucio H., Moraes, Carolina B., Pascoalino, Bruno S., Alcântara, Laura M., Bertolacini, Claudia P., Fontana, Vanessa, Wittig, Ulrike, Müller, Wolfgang, Wade, Rebecca C., Hunter, William N., Mangani, Stefano, Costantino, Luca, Costi, Maria P.
Publicado 2017

Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform

por Moraes, Carolina B., Witt, Gesa, Kuzikov, Maria, Ellinger, Bernhard, Calogeropoulou, Theodora, Prousis, Kyriakos C., Mangani, Stefano, Di Pisa, Flavio, Landi, Giacomo, Iacono, Lucia Dello, Pozzi, Cecilia, Freitas-Junior, Lucio H., dos Santos Pascoalino, Bruno, Bertolacini, Claudia P., Behrens, Birte, Keminer, Oliver, Leu, Jennifer, Wolf, Markus, Reinshagen, Jeanette, Cordeiro-da-Silva, Anabela, Santarem, Nuno, Venturelli, Alberto, Wrigley, Stephen, Karunakaran, Deepa, Kebede, Bethlehem, Pöhner, Ina, Müller, Wolfgang, Panecka-Hofman, Joanna, Wade, Rebecca C., Fenske, Martina, Clos, Joachim, Alunda, José María, Corral, María Jesús, Uliassi, Elisa, Bolognesi, Maria Laura, Linciano, Pasquale, Quotadamo, Antonio, Ferrari, Stefania, Santucci, Matteo, Borsari, Chiara, Costi, Maria Paola, Gul, Sheraz
Publicado 2019