Disease-associated protein seeding suggests a dissociation between misfolded protein accumulation and neurodegeneration in prion disease

por Alibhai, James, Diack, Abigail, Manson, Jean
Publicado 2017

Public health risks from subclinical variant CJD

por Diack, Abigail B., Will, Robert G., Manson, Jean C.
Publicado 2017

Insights into Mechanisms of Chronic Neurodegeneration

por Diack, Abigail B., Alibhai, James D., Barron, Rona, Bradford, Barry, Piccardo, Pedro, Manson, Jean C.
Publicado 2016

Prion infectivity in the spleen of a PRNP heterozygous individual with subclinical variant Creutzfeldt–Jakob disease

por Bishop, Matthew T., Diack, Abigail B., Ritchie, Diane L., Ironside, James W., Will, Robert G., Manson, Jean C.
Publicado 2013

Variant Creutzfeldt-Jakob disease strain is identical in individuals of two PRNP codon 129 genotypes

por Diack, Abigail B, Boyle, Aileen, Plinston, Christopher, Hunt, Emma, Bishop, Matthew T, Will, Robert G, Manson, Jean C
Publicado 2019

No Adaptation of the Prion Strain in a Heterozygous Case of Variant Creutzfeldt-Jakob Disease

por Boyle, Aileen, Plinston, Chris, Laing, Fraser, Mackenzie, Graeme, Will, Robert G., Manson, Jean C., Diack, Abigail B.
Publicado 2020

Spermine increases acetylation of tubulins and facilitates autophagic degradation of prion aggregates

por Phadwal, Kanchan, Kurian, Dominic, Salamat, Muhammad Khalid F., MacRae, Vicky E., Diack, Abigail B., Manson, Jean C.
Publicado 2018

Traits associated with innate and adaptive immunity in pigs: heritability and associations with performance under different health status conditions

por Clapperton, Mary, Diack, Abigail B, Matika, Oswald, Glass, Elizabeth J, Gladney, Christy D, Mellencamp, Martha A, Hoste, Annabelle, Bishop, Stephen C
Publicado 2009

Variant CJD: 18 years of research and surveillance

por Diack, Abigail B, Head, Mark W, McCutcheon, Sandra, Boyle, Aileen, Knight, Richard, Ironside, James W, Manson, Jean C, Will, Robert G
Publicado 2014

The Glycosylation Status of PrP(C) Is a Key Factor in Determining Transmissible Spongiform Encephalopathy Transmission between Species

por Wiseman, Frances K., Cancellotti, Enrico, Piccardo, Pedro, Iremonger, Kayleigh, Boyle, Aileen, Brown, Deborah, Ironside, James W., Manson, Jean C., Diack, Abigail B.
Publicado 2015

Ablation of Prion Protein in Wild Type Human Amyloid Precursor Protein (APP) Transgenic Mice Does Not Alter The Proteolysis of APP, Levels of Amyloid-β or Pathologic Phenotype

por Whitehouse, Isobel J., Brown, Deborah, Baybutt, Herbert, Diack, Abigail B., Kellett, Katherine A. B., Piccardo, Pedro, Manson, Jean C., Hooper, Nigel M.
Publicado 2016

Similarities of Variant Creutzfeldt-Jakob Disease Strain in Mother and Son in Spain to UK Reference Case

por Diack, Abigail B., Boyle, Aileen, Ritchie, Diane, Plinston, Chris, Kisielewski, Dorothy, de Pedro-Cuesta, Jesús, Rábano, Alberto, Will, Robert G., Manson, Jean C.
Publicado 2017

Identification of a homology-independent linchpin domain controlling mouse and bank vole prion protein conversion

por Burke, Cassandra M., Mark, Kenneth M. K., Walsh, Daniel J., Noble, Geoffrey P., Steele, Alexander D., Diack, Abigail B., Manson, Jean C., Watts, Joel C., Supattapone, Surachai
Publicado 2020

Conservation of vCJD Strain Properties After Extraction and In Vitro Propagation of PrP(Sc) from Archived Formalin-Fixed Brain and Appendix Tissues Using Highly Sensitive Protein M...

por Suleiman, Suzanne, McGuire, Lynne I., Chong, Angela, Ritchie, Diane L., Boyle, Aileen, McManus, Lee, Brydon, Fraser, Smith, Colin, Knight, Richard, Green, Alison, Diack, Abigail B., Barria, Marcelo A.
Publicado 2023

Variably Protease-Sensitive Prionopathy, a Unique Prion Variant with Inefficient Transmission Properties

por Diack, Abigail B., Ritchie, Diane L., Peden, Alexander H., Brown, Deborah, Boyle, Aileen, Morabito, Laura, Maclennan, David, Burgoyne, Paul, Jansen, Casper, Knight, Richard S., Piccardo, Pedro, Ironside, James W., Manson, Jean C.
Publicado 2014

Constant Transmission Properties of Variant Creutzfeldt-Jakob Disease in 5 Countries

por Diack, Abigail B., Ritchie, Diane, Bishop, Matthew, Pinion, Victoria, Brandel, Jean-Philippe, Haik, Stephane, Tagliavini, Fabrizio, Van Duijn, Cornelia, Belay, Ermias D., Gambetti, Pierluigi, Schonberger, Lawrence B., Piccardo, Pedro, Will, Robert G., Manson, Jean C.
Publicado 2012