Chagas Disease Drug Discovery in Latin America—A Mini Review of Antiparasitic Agents Explored Between 2010 and 2021

por de Oliveira, Ramon G., Cruz, Luiza R., Mollo, María C., Dias, Luiz C., Kratz, Jadel M.
Publicado 2021

Structure-Based and Molecular Modeling Studies for the Discovery of Cyclic Imides as Reversible Cruzain Inhibitors With Potent Anti-Trypanosoma cruzi Activity

por Ferreira, Rafael A. A., Pauli, Ivani, Sampaio, Thiago S., de Souza, Mariana L., Ferreira, Leonardo L. G., Magalhães, Luma G., Rezende, Celso de O., Ferreira, Rafaela S., Krogh, Renata, Dias, Luiz C., Andricopulo, Adriano D.
Publicado 2019

Hit-to-lead optimization of a benzene sulfonamide series for potential antileishmanial agents

por Koovits, Paul J., Dessoy, Marco A., Matheeussen, An, Maes, Louis, Caljon, Guy, Ferreira, Leonardo L. G., Chelucci, Rafael C., Michelan-Duarte, Simone, Andricopulo, Adriano D., Campbell, Simon, Kratz, Jadel M., Mowbray, Charles E., Dias, Luiz C.
Publicado 2020

Multiparameter Optimization of Trypanocidal Cruzain Inhibitors With In Vivo Activity and Favorable Pharmacokinetics

por Pauli, Ivani, Rezende Jr., Celso de O., Slafer, Brian W., Dessoy, Marco A., de Souza, Mariana L., Ferreira, Leonardo L. G., Adjanohun, Abraham L. M., Ferreira, Rafaela S., Magalhães, Luma G., Krogh, Renata, Michelan-Duarte, Simone, Del Pintor, Ricardo Vaz, da Silva, Fernando B. R., Cruz, Fabio C., Dias, Luiz C., Andricopulo, Adriano D.
Publicado 2022