Machine learning links T cell function and spatial localization to neoadjuvant immunotherapy and clinical outcome in pancreatic cancer

por Blise, Katie E., Sivagnanam, Shamilene, Betts, Courtney B., Betre, Konjit, Kirchberger, Nell, Tate, Benjamin, Furth, Emma E., Dias Costa, Andressa, Nowak, Jonathan A., Wolpin, Brian M., Vonderheide, Robert H., Goecks, Jeremy, Coussens, Lisa M., Byrne, Katelyn T.
Publicado 2023

Multicenter randomized controlled trial of neoadjuvant chemoradiotherapy alone or in combination with pembrolizumab in patients with resectable or borderline resectable pancreatic...

por Katz, Matthew H G, Petroni, Gina R, Bauer, Todd, Reilley, Matthew J, Wolpin, Brian M, Stucky, Chee-Chee, Bekaii-Saab, Tanios S, Elias, Rawad, Merchant, Nipun, Dias Costa, Andressa, Lenehan, Patrick, Cardot-Ruffino, Victoire, Rodig, Scott, Pfaff, Kathleen, Dougan, Stephanie K, Nowak, Jonathan Andrew, Varadhachary, Gauri R, Slingluff, Craig L, Rahma, Osama
Publicado 2023

Bayesian risk prediction model for colorectal cancer mortality through integration of clinicopathologic and genomic data

por Zhao, Melissa, Lau, Mai Chan, Haruki, Koichiro, Väyrynen, Juha P., Gurjao, Carino, Väyrynen, Sara A., Dias Costa, Andressa, Borowsky, Jennifer, Fujiyoshi, Kenji, Arima, Kota, Hamada, Tsuyoshi, Lennerz, Jochen K., Fuchs, Charles S., Nishihara, Reiko, Chan, Andrew T., Ng, Kimmie, Zhang, Xuehong, Meyerhardt, Jeffrey A., Song, Mingyang, Wang, Molin, Giannakis, Marios, Nowak, Jonathan A., Yu, Kun-Hsing, Ugai, Tomotaka, Ogino, Shuji
Publicado 2023

An integrated analysis of lymphocytic reaction, tumour molecular characteristics and patient survival in colorectal cancer

por Haruki, Koichiro, Kosumi, Keisuke, Li, Peilong, Arima, Kota, Väyrynen, Juha P., Lau, Mai Chan, Twombly, Tyler S., Hamada, Tsuyoshi, Glickman, Jonathan N., Fujiyoshi, Kenji, Chen, Yang, Du, Chunxia, Guo, Chunguang, Väyrynen, Sara A., Dias Costa, Andressa, Song, Mingyang, Chan, Andrew T., Meyerhardt, Jeffrey A., Nishihara, Reiko, Fuchs, Charles S., Liu, Li, Zhang, Xuehong, Wu, Kana, Giannakis, Marios, Nowak, Jonathan A., Ogino, Shuji
Publicado 2020

Prognostic significance of myeloid immune cells and their spatial distribution in the colorectal cancer microenvironment

por Väyrynen, Juha P, Haruki, Koichiro, Väyrynen, Sara A, Lau, Mai Chan, Dias Costa, Andressa, Borowsky, Jennifer, Zhao, Melissa, Ugai, Tomotaka, Kishikawa, Junko, Akimoto, Naohiko, Zhong, Rong, Shi, Shanshan, Chang, Tzuu-Wang, Fujiyoshi, Kenji, Arima, Kota, Twombly, Tyler S, Da Silva, Annacarolina, Song, Mingyang, Wu, Kana, Zhang, Xuehong, Chan, Andrew T, Nishihara, Reiko, Fuchs, Charles S, Meyerhardt, Jeffrey A, Giannakis, Marios, Ogino, Shuji, Nowak, Jonathan A
Publicado 2021

Neoadjuvant Selicrelumab, an Agonist CD40 Antibody, Induces Changes in the Tumor Microenvironment in Patients with Resectable Pancreatic Cancer

por Byrne, Katelyn T., Betts, Courtney B., Mick, Rosemarie, Sivagnanam, Shamilene, Bajor, David L., Laheru, Daniel A., Chiorean, E. Gabriela, O'Hara, Mark H., Liudahl, Shannon M., Newcomb, Craig, Alanio, Cécile, Ferreira, Ana P., Park, Byung S., Ohtani, Takuya, Huffman, Austin P., Väyrynen, Sara A., Dias Costa, Andressa, Kaiser, Judith C., Lacroix, Andreanne M., Redlinger, Colleen, Stern, Martin, Nowak, Jonathan A., Wherry, E. John, Cheever, Martin A., Wolpin, Brian M., Furth, Emma E., Jaffee, Elizabeth M., Coussens, Lisa M., Vonderheide, Robert H.
Publicado 2021