Contributions of Na(V)1.8 and Na(V)1.9 to excitability in human induced pluripotent stem-cell derived somatosensory neurons

por Alsaloum, Matthew, Labau, Julie I. R., Liu, Shujun, Estacion, Mark, Zhao, Peng, Dib-Hajj, Fadia, Waxman, Stephen G.
Publicado 2021

The fates of internalized Na(V)1.7 channels in sensory neurons: Retrograde cotransport with other ion channels, axon-specific recycling, and degradation

por Higerd-Rusli, Grant P., Tyagi, Sidharth, Liu, Shujun, Dib-Hajj, Fadia B., Waxman, Stephen G., Dib-Hajj, Sulayman D.
Publicado 2022

Conserved but not critical: Trafficking and function of Na(V)1.7 are independent of highly conserved polybasic motifs

por Tyagi, Sidharth, Sarveswaran, Nivedita, Higerd-Rusli, Grant P., Liu, Shujun, Dib-Hajj, Fadia B., Waxman, Stephen G., Dib-Hajj, Sulayman D.
Publicado 2023

Inflammation differentially controls transport of depolarizing Nav versus hyperpolarizing Kv channels to drive rat nociceptor activity

por Higerd-Rusli, Grant P., Tyagi, Sidharth, Baker, Christopher A., Liu, Shujun, Dib-Hajj, Fadia B., Dib-Hajj, Sulayman D., Waxman, Stephen G.
Publicado 2023

Paclitaxel increases axonal localization and vesicular trafficking of Na(v)1.7

por Akin, Elizabeth J, Alsaloum, Matthew, Higerd, Grant P, Liu, Shujun, Zhao, Peng, Dib-Hajj, Fadia B, Waxman, Stephen G, Dib-Hajj, Sulayman D
Publicado 2021

Conditional knockout of Na(V)1.6 in adult mice ameliorates neuropathic pain

por Chen, Lubin, Huang, Jianying, Zhao, Peng, Persson, Anna-Karin, Dib-Hajj, Fadia B., Cheng, Xiaoyang, Tan, Andrew, Waxman, Stephen G., Dib-Hajj, Sulayman D.
Publicado 2018

Paclitaxel effects on axonal localization and vesicular trafficking of Na(V)1.8

por Baker, Christopher A., Tyagi, Sidharth, Higerd-Rusli, Grant P., Liu, Shujun, Zhao, Peng, Dib-Hajj, Fadia B., Waxman, Stephen G., Dib-Hajj, Sulayman D.
Publicado 2023

A Novel Gain-of-Function Nav1.9 Mutation in a Child With Episodic Pain

por Huang, Jianying, Estacion, Mark, Zhao, Peng, Dib-Hajj, Fadia B., Schulman, Betsy, Abicht, Angela, Kurth, Ingo, Brockmann, Knut, Waxman, Stephen G., Dib-Hajj, Sulayman D.
Publicado 2019

Building sensory axons: Delivery and distribution of Na(V)1.7 channels and effects of inflammatory mediators

por Akin, Elizabeth J., Higerd, Grant P., Mis, Malgorzata A., Tanaka, Brian S., Adi, Talia, Liu, Shujun, Dib-Hajj, Fadia B., Waxman, Stephen G., Dib-Hajj, Sulayman D.
Publicado 2019

KCNQ variants and pain modulation: a missense variant in Kv7.3 contributes to pain resilience

por Yuan, Jun-Hui, Estacion, Mark, Mis, Malgorzata A, Tanaka, Brian S, Schulman, Betsy R, Chen, Lubin, Liu, Shujun, Dib-Hajj, Fadia B, Dib-Hajj, Sulayman D, Waxman, Stephen G
Publicado 2021

Lacosamide Inhibition of Na(V)1.7 Channels Depends on its Interaction With the Voltage Sensor Domain and the Channel Pore

por Labau, Julie I. R., Alsaloum, Matthew, Estacion, Mark, Tanaka, Brian, Dib-Hajj, Fadia B., Lauria, Giuseppe, Smeets, Hubert J. M., Faber, Catharina G., Dib-Hajj, Sulayman, Waxman, Stephen G.
Publicado 2021