The fates of internalized Na(V)1.7 channels in sensory neurons: Retrograde cotransport with other ion channels, axon-specific recycling, and degradation

por Higerd-Rusli, Grant P., Tyagi, Sidharth, Liu, Shujun, Dib-Hajj, Fadia B., Waxman, Stephen G., Dib-Hajj, Sulayman D.
Publicado 2022

Conserved but not critical: Trafficking and function of Na(V)1.7 are independent of highly conserved polybasic motifs

por Tyagi, Sidharth, Sarveswaran, Nivedita, Higerd-Rusli, Grant P., Liu, Shujun, Dib-Hajj, Fadia B., Waxman, Stephen G., Dib-Hajj, Sulayman D.
Publicado 2023

Inflammation differentially controls transport of depolarizing Nav versus hyperpolarizing Kv channels to drive rat nociceptor activity

por Higerd-Rusli, Grant P., Tyagi, Sidharth, Baker, Christopher A., Liu, Shujun, Dib-Hajj, Fadia B., Dib-Hajj, Sulayman D., Waxman, Stephen G.
Publicado 2023

Paclitaxel increases axonal localization and vesicular trafficking of Na(v)1.7

por Akin, Elizabeth J, Alsaloum, Matthew, Higerd, Grant P, Liu, Shujun, Zhao, Peng, Dib-Hajj, Fadia B, Waxman, Stephen G, Dib-Hajj, Sulayman D
Publicado 2021

Effects of ranolazine on wild-type and mutant hNa(v)1.7 channels and on DRG neuron excitability

por Estacion, Mark, Waxman, Stephen G, Dib-Hajj, Sulayman D
Publicado 2010

Multiple myosin motors interact with sodium/potassium-ATPase alpha 1 subunits

por Dash, Bhagirathi, Dib-Hajj, Sulayman D., Waxman, Stephen G.
Publicado 2018

Conditional knockout of Na(V)1.6 in adult mice ameliorates neuropathic pain

por Chen, Lubin, Huang, Jianying, Zhao, Peng, Persson, Anna-Karin, Dib-Hajj, Fadia B., Cheng, Xiaoyang, Tan, Andrew, Waxman, Stephen G., Dib-Hajj, Sulayman D.
Publicado 2018

Paclitaxel effects on axonal localization and vesicular trafficking of Na(V)1.8

por Baker, Christopher A., Tyagi, Sidharth, Higerd-Rusli, Grant P., Liu, Shujun, Zhao, Peng, Dib-Hajj, Fadia B., Waxman, Stephen G., Dib-Hajj, Sulayman D.
Publicado 2023

A Novel Gain-of-Function Nav1.9 Mutation in a Child With Episodic Pain

por Huang, Jianying, Estacion, Mark, Zhao, Peng, Dib-Hajj, Fadia B., Schulman, Betsy, Abicht, Angela, Kurth, Ingo, Brockmann, Knut, Waxman, Stephen G., Dib-Hajj, Sulayman D.
Publicado 2019

Building sensory axons: Delivery and distribution of Na(V)1.7 channels and effects of inflammatory mediators

por Akin, Elizabeth J., Higerd, Grant P., Mis, Malgorzata A., Tanaka, Brian S., Adi, Talia, Liu, Shujun, Dib-Hajj, Fadia B., Waxman, Stephen G., Dib-Hajj, Sulayman D.
Publicado 2019

Lessons learned in translating pain knowledge into practice

por Becker, Juliane, Effraim, Philip R., Dib-Hajj, Sulayman, Rittner, Heike L.
Publicado 2023

Mutation I136V alters electrophysiological properties of the Na(V)1.7 channel in a family with onset of erythromelalgia in the second decade

por Cheng, Xiaoyang, Dib-Hajj, Sulayman D, Tyrrell, Lynda, Waxman, Stephen G
Publicado 2008

Nonmuscle myosin II isoforms interact with sodium channel alpha subunits

por Dash, Bhagirathi, Han, Chongyang, Waxman, Stephen G, Dib-Hajj, Sulayman D
Publicado 2018

KCNQ variants and pain modulation: a missense variant in Kv7.3 contributes to pain resilience

por Yuan, Jun-Hui, Estacion, Mark, Mis, Malgorzata A, Tanaka, Brian S, Schulman, Betsy R, Chen, Lubin, Liu, Shujun, Dib-Hajj, Fadia B, Dib-Hajj, Sulayman D, Waxman, Stephen G
Publicado 2021

Lacosamide Inhibition of Na(V)1.7 Channels Depends on its Interaction With the Voltage Sensor Domain and the Channel Pore

por Labau, Julie I. R., Alsaloum, Matthew, Estacion, Mark, Tanaka, Brian, Dib-Hajj, Fadia B., Lauria, Giuseppe, Smeets, Hubert J. M., Faber, Catharina G., Dib-Hajj, Sulayman, Waxman, Stephen G.
Publicado 2021

Kv7-specific activators hyperpolarize resting membrane potential and modulate human iPSC-derived sensory neuron excitability

por Estacion, Mark, Liu, Shujun, Cheng, Xiaoyang, Dib-Hajj, Sulayman, Waxman, Stephen G.
Publicado 2023

Expression of Nav1.7 in DRG neurons extends from peripheral terminals in the skin to central preterminal branches and terminals in the dorsal horn

por Black, Joel A, Frézel, Noémie, Dib-Hajj, Sulayman D, Waxman, Stephen G
Publicado 2012

Brain activity associated with pain in inherited erythromelalgia: stimulus-free pain engages brain areas involved in valuation and learning

por Geha, Paul, Schulman, Betsy R., Dib-Hajj, Sulayman D., Waxman, Stephen G.
Publicado 2018

Oral Administration of PF-01247324, a Subtype-Selective Nav1.8 Blocker, Reverses Cerebellar Deficits in a Mouse Model of Multiple Sclerosis

por Shields, Shannon D., Butt, Richard P., Dib-Hajj, Sulayman D., Waxman, Stephen G.
Publicado 2015

Preferential Targeting of Na(v)1.6 Voltage-Gated Na(+) Channels to the Axon Initial Segment during Development

por Akin, Elizabeth J., Solé, Laura, Dib-Hajj, Sulayman D., Waxman, Stephen G., Tamkun, Michael M.
Publicado 2015