Morphing of Ibogaine: A Successful Attempt into the Search for Sigma-2 Receptor Ligands

por Floresta, Giuseppe, Dichiara, Maria, Gentile, Davide, Prezzavento, Orazio, Marrazzo, Agostino, Rescifina, Antonio, Amata, Emanuele
Publicado 2019

Sigma-2 receptor ligands QSAR model dataset

por Rescifina, Antonio, Floresta, Giuseppe, Marrazzo, Agostino, Parenti, Carmela, Prezzavento, Orazio, Nastasi, Giovanni, Dichiara, Maria, Amata, Emanuele
Publicado 2017

Discovery and computational studies of piperidine/piperazine-based compounds endowed with sigma receptor affinity

por De Luca, Laura, Lombardo, Lisa, Mirabile, Salvatore, Marrazzo, Agostino, Dichiara, Maria, Cosentino, Giuseppe, Amata, Emanuele, Gitto, Rosaria
Publicado 2023

Cytotoxicity Profiles and Neuroprotective Properties of the Novel Ifenprodil Analogues as Sigma Ligands

por Zampieri, Daniele, Calabretti, Antonella, Romano, Maurizio, Fortuna, Sara, Collina, Simona, Amata, Emanuele, Dichiara, Maria, Marrazzo, Agostino, Mamolo, Maria Grazia
Publicado 2023

Discovery, affinity maturation and multimerization of small molecule ligands against human tyrosinase and tyrosinase-related protein 1

por Catalano, Marco, Bassi, Gabriele, Rotondi, Giulia, Khettabi, Lyna, Dichiara, Maria, Murer, Patrizia, Scheuermann, Jörg, Soler-Lopez, Montserrat, Neri, Dario
Publicado 2020

Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors

por Amata, Emanuele, Marrazzo, Agostino, Dichiara, Maria, Modica, Maria N., Salerno, Loredana, Prezzavento, Orazio, Nastasi, Giovanni, Rescifina, Antonio, Romeo, Giuseppe, Pittalà, Valeria
Publicado 2017

Novel N-normetazocine Derivatives with Opioid Agonist/Sigma-1 Receptor Antagonist Profile as Potential Analgesics in Inflammatory Pain

por Turnaturi, Rita, Chiechio, Santina, Pasquinucci, Lorella, Spoto, Salvatore, Costanzo, Giuliana, Dichiara, Maria, Piana, Silvia, Grasso, Margherita, Amata, Emanuele, Marrazzo, Agostino, Parenti, Carmela
Publicado 2022

Synthesis, Computational Insights, and Evaluation of Novel Sigma Receptors Ligands

por Dichiara, Maria, Ambrosio, Francesca Alessandra, Barbaraci, Carla, González-Cano, Rafael, Costa, Giosuè, Parenti, Carmela, Marrazzo, Agostino, Pasquinucci, Lorella, Cobos, Enrique J., Alcaro, Stefano, Amata, Emanuele
Publicado 2023

Combination of Heme Oxygenase-1 Inhibition and Sigma Receptor Modulation for Anticancer Activity

por Romeo, Giuseppe, Ciaffaglione, Valeria, Amata, Emanuele, Dichiara, Maria, Calabrese, Loredana, Vanella, Luca, Sorrenti, Valeria, Grosso, Salvo, D’Amico, Agata Grazia, D’Agata, Velia, Intagliata, Sebastiano, Salerno, Loredana
Publicado 2021

New Insights into the Opioid Analgesic Profile of cis-(−)-N-Normetazocine-derived Ligands

por Costanzo, Giuliana, Turnaturi, Rita, Parenti, Carmela, Spoto, Salvatore, Piana, Silvia, Dichiara, Maria, Zagni, Chiara, Galambos, Anna Rita, Essmat, Nariman, Marrazzo, Agostino, Amata, Emanuele, Al-Khrasani, Mahmoud, Pasquinucci, Lorella
Publicado 2023

Haloperidol Metabolite II Valproate Ester (S)-(−)-MRJF22: Preliminary Studies as a Potential Multifunctional Agent Against Uveal Melanoma

por Barbaraci, Carla, Giurdanella, Giovanni, Leotta, Claudia Giovanna, Longo, Anna, Amata, Emanuele, Dichiara, Maria, Pasquinucci, Lorella, Turnaturi, Rita, Prezzavento, Orazio, Cacciatore, Ivana, Zuccarello, Elisa, Lupo, Gabriella, Pitari, Giovanni Mario, Anfuso, Carmelina Daniela, Marrazzo, Agostino
Publicado 2021

Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents

por Fallica, Antonino Nicolò, Barbaraci, Carla, Amata, Emanuele, Pasquinucci, Lorella, Turnaturi, Rita, Dichiara, Maria, Intagliata, Sebastiano, Gariboldi, Marzia Bruna, Marras, Emanuela, Orlandi, Viviana Teresa, Ferroni, Claudia, Martini, Cecilia, Rescifina, Antonio, Gentile, Davide, Varchi, Greta, Marrazzo, Agostino
Publicado 2021

Correction to “Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents”

por Fallica, Antonino Nicolò, Barbaraci, Carla, Amata, Emanuele, Pasquinucci, Lorella, Turnaturi, Rita, Dichiara, Maria, Intagliata, Sebastiano, Gariboldi, Marzia Bruna, Marras, Emanuela, Orlandi, Viviana Teresa, Ferroni, Claudia, Martini, Cecilia, Rescifina, Antonio, Gentile, Davide, Varchi, Greta, Marrazzo, Agostino
Publicado 2022

Discovery of AD258 as a Sigma Receptor Ligand with Potent Antiallodynic Activity

por Dichiara, Maria, Ambrosio, Francesca Alessandra, Lee, Sang Min, Ruiz-Cantero, M. Carmen, Lombino, Jessica, Coricello, Adriana, Costa, Giosuè, Shah, Dhara, Costanzo, Giuliana, Pasquinucci, Lorella, Son, Kyung No, Cosentino, Giuseppe, González-Cano, Rafael, Marrazzo, Agostino, Aakalu, Vinay Kumar, Cobos, Enrique J., Alcaro, Stefano, Amata, Emanuele
Publicado 2023

Structural and Molecular Insight into Piperazine and Piperidine Derivatives as Histamine H(3) and Sigma-1 Receptor Antagonists with Promising Antinociceptive Properties

por Szczepańska, Katarzyna, Podlewska, Sabina, Dichiara, Maria, Gentile, Davide, Patamia, Vincenzo, Rosier, Niklas, Mönnich, Denise, Ruiz Cantero, Ma Carmen, Karcz, Tadeusz, Łażewska, Dorota, Siwek, Agata, Pockes, Steffen, Cobos, Enrique J., Marrazzo, Agostino, Stark, Holger, Rescifina, Antonio, Bojarski, Andrzej J., Amata, Emanuele, Kieć-Kononowicz, Katarzyna
Publicado 2021

Structure–Property Optimization of a Series of Imidazopyridines for Visceral Leishmaniasis

por Dichiara, Maria, Simpson, Quillon J., Quotadamo, Antonio, Jalani, Hitesh B., Huang, Anson X., Millard, Caroline C., Klug, Dana M., Tse, Edwin G., Todd, Matthew H., Silva, Daniel Gedder, da Silva Emery, Flavio, Carlson, J. Eric, Zheng, Shao-Liang, Vleminckx, Margot, Matheeussen, An, Caljon, Guy, Pollastri, Michael P., Sjö, Peter, Perry, Benjamin, Ferrins, Lori
Publicado 2023

Dual Piperidine-Based Histamine H(3) and Sigma-1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain

por Szczepańska, Katarzyna, Karcz, Tadeusz, Dichiara, Maria, Mogilski, Szczepan, Kalinowska-Tłuścik, Justyna, Pilarski, Bogusław, Leniak, Arkadiusz, Pietruś, Wojciech, Podlewska, Sabina, Popiołek-Barczyk, Katarzyna, Humphrys, Laura J., Ruiz-Cantero, M. Carmen, Reiner-Link, David, Leitzbach, Luisa, Łażewska, Dorota, Pockes, Steffen, Górka, Michał, Zmysłowski, Adam, Calmels, Thierry, Cobos, Enrique J., Marrazzo, Agostino, Stark, Holger, Bojarski, Andrzej J., Amata, Emanuele, Kieć-Kononowicz, Katarzyna
Publicado 2023