Circulating tumor cells: silent predictors of metastasis

por Zhou, LanLan, Dicker, David T., Matthew, Elizabeth, El-Deiry, Wafik S., Alpaugh, R. Katherine
Publicado 2017

Anti-cancer efficacy including Rb-deficient tumors and VHL-independent HIF1α proteasomal destabilization by dual targeting of CDK1 or CDK4/6 and HSP90

por Zhao, Shuai, Zhou, Lanlan, Dicker, David T., Lev, Avital, Zhang, Shengliang, Ross, Eric, El-Deiry, Wafik S.
Publicado 2021

Detection of circulating tumor cells in the cerebrospinal fluid of a patient with a solitary metastasis from breast cancer: A case report

por PATEL, AKSHAL S., ALLEN, JOSHUA E., DICKER, DAVID T., SHEEHAN, JONAS M., GLANTZ, MICHAEL J., EL-DEIRY, WAFIK S.
Publicado 2014

P53-independent partial restoration of the p53 pathway in tumors with mutated p53 through ATF4 transcriptional modulation by ERK1/2 and CDK9

por Tian, Xiaobing, Ahsan, Nagib, Lulla, Amriti, Lev, Avital, Abbosh, Philip, Dicker, David T., Zhang, Shengliang, El-Deiry, Wafik S.
Publicado 2021

Identification of TRAIL-inducing compounds highlights small molecule ONC201/TIC10 as a unique anti-cancer agent that activates the TRAIL pathway

por Allen, Joshua E, Krigsfeld, Gabriel, Patel, Luv, Mayes, Patrick A, Dicker, David T, Wu, Gen Sheng, El-Deiry, Wafik S
Publicado 2015

Antitumorigenic effect of combination treatment with ONC201 and TRAIL in endometrial cancer in vitro and in vivo

por Ray, Jocelyn E., Ralff, Marie D., Jhaveri, Aakash, Zhou, Lanlan, Dicker, David T., Ross, Eric A., El-Deiry, Wafik S.
Publicado 2021

Identification and enumeration of circulating tumor cells in the cerebrospinal fluid of breast cancer patients with central nervous system metastases

por Patel, Akshal S., Allen, Joshua E., Dicker, David T., Peters, Kristi L., Sheehan, Jonas M., Glantz, Michael J., El-Deiry, Wafik S.
Publicado 2011

The Akt Inhibitor ISC-4 Synergizes with Cetuximab in 5-FU-Resistant Colon Cancer

por Allen, Joshua E., Gallant, Jean-Nicolas, Dicker, David T., Amin, Shantu, Irby, Rosalyn B., Sharma, Arun K., El-Deiry, Wafik S.
Publicado 2013

Correction: The Akt Inhibitor ISC-4 Synergizes with Cetuximab in 5-FU-Resistant Colon Cancer

por Allen, Joshua E., Gallant, Jean-Nicolas, Dicker, David T., Amin, Shantu, Irby, Rosalyn B., Sharma, Arun K., El-Deiry, Wafik S.
Publicado 2013

Sorafenib Sensitizes Solid Tumors to Apo2L/TRAIL and Apo2L/TRAIL Receptor Agonist Antibodies by the Jak2-Stat3-Mcl1 Axis

por Abdulghani, Junaid, Allen, Joshua E., Dicker, David T., Liu, Yingqiu Yvette, Goldenberg, David, Smith, Charles D., Humphreys, Robin, El-Deiry, Wafik S.
Publicado 2013

A subset of CB002 xanthine analogs bypass p53-signaling to restore a p53 transcriptome and target an S-phase cell cycle checkpoint in tumors with mutated-p53

por Hernandez Borrero, Liz, Dicker, David T, Santiago, John, Sanders, Jennifer, Tian, Xiaobing, Ahsan, Nagib, Lev, Avital, Zhou, Lanlan, El-Deiry, Wafik S
Publicado 2021

The angular structure of ONC201, a TRAIL pathway-inducing compound, determines its potent anti-cancer activity

por Wagner, Jessica, Kline, Christina Leah, Pottorf, Richard S., Nallaganchu, Bhaskara Rao, Olson, Gary L., Dicker, David T., Allen, Joshua E., El-Deiry, Wafik S.
Publicado 2015

Apoptotic circulating tumor cells (CTCs) in the peripheral blood of metastatic colorectal cancer patients are associated with liver metastasis but not CTCs

por Allen, Joshua E., Saroya, Bikramajit Singh, Kunkel, Miriam, Dicker, David T., Das, Avisnata, Peters, Kristi L., Joudeh, Jamal, Zhu, Junjia, El-Deiry, Wafik S.
Publicado 2013

TRAIL receptor agonists convert the response of breast cancer cells to ONC201 from anti-proliferative to apoptotic

por Ralff, Marie D., Jhaveri, Aakash, Ray, Jocelyn E., Zhou, Lanlan, Lev, Avital, Campbell, Kerry S., Dicker, David T., Ross, Eric A., El-Deiry, Wafik S.
Publicado 2020

Role of Dopamine Receptors in the Anticancer Activity of ONC201()()

por Kline, Christina Leah B., Ralff, Marie D., Lulla, Amriti R., Wagner, Jessica M., Abbosh, Phillip H., Dicker, David T., Allen, Joshua E., El-Deiry, Wafik S.
Publicado 2017

Anti-pancreatic cancer activity of ONC212 involves the unfolded protein response (UPR) and is reduced by IGF1-R and GRP78/BIP

por Lev, Avital, Lulla, Amriti R., Wagner, Jessica, Ralff, Marie D., Kiehl, Joshua B., Zhou, Yan, Benes, Cyril H., Prabhu, Varun V., Oster, Wolfgang, Astsaturov, Igor, Dicker, David T., El-Deiry, Wafik S.
Publicado 2017

A multiplexed marker-based algorithm for diagnosis of carcinoma of unknown primary using circulating tumor cells

por Matthew, Elizabeth M., Zhou, Lanlan, Yang, Zhaohai, Dicker, David T., Holder, Sheldon L., Lim, Bora, Harouaka, Ramdane, Zheng, Si-Yang, Drabick, Joseph J., Lamparella, Nicholas E., Truica, Cristina I., El-Deiry, Wafik S.
Publicado 2015

Discovery and clinical introduction of first-in-class imipridone ONC201

por Allen, Joshua E., Kline, C. Leah B., Prabhu, Varun V., Wagner, Jessica, Ishizawa, Jo, Madhukar, Neel, Lev, Avital, Baumeister, Marie, Zhou, Lanlan, Lulla, Amriti, Stogniew, Martin, Schalop, Lee, Benes, Cyril, Kaufman, Howard L., Pottorf, Richard S., Nallaganchu, B. Rao, Olson, Gary L., Al-Mulla, Fahd, Duvic, Madeleine, Wu, Gen Sheng, Dicker, David T., Talekar, Mala K., Lim, Bora, Elemento, Olivier, Oster, Wolfgang, Bertino, Joseph, Flaherty, Keith, Wang, Michael L., Borthakur, Gautam, Andreeff, Michael, Stein, Mark, El-Deiry, Wafik S.
Publicado 2016

Correction: Discovery and clinical introduction of first-in-class imipridone ONC201

por Allen, Joshua E., Kline, C. Leah B., Prabhu, Varun V., Wagner, Jessica, Ishizawa, Jo, Madhukar, Neel, Lev, Avital, Baumeister, Marie, Zhou, Lanlan, Lulla, Amriti, Stogniew, Martin, Schalop, Lee, Benes, Cyril, Kaufman, Howard L., Pottorf, Richard S., Nallaganchu, B. Rao, Olson, Gary L., Al-Mulla, Fahd, Duvic, Madeleine, Wu, Gen Sheng, Dicker, David T., Talekar, Mala K., Lim, Bora, Elemento, Olivier, Oster, Wolfgang, Bertino, Joseph, Flaherty, Keith, Wang, Michael L., Borthakur, Gautam, Andreeff, Michael, Stein, Mark, El-Deiry, Wafik S.
Publicado 2021