The Metamorphic Nature of the Tau Protein: Dynamic Flexibility Comes at a Cost

por Sabbagh, Jonathan J., Dickey, Chad A.
Publicado 2016

Potential synergy between tau aggregation inhibitors and tau chaperone modulators

por Blair, Laura J, Zhang, Bo, Dickey, Chad A
Publicado 2013

Pharmacologic reductions of total tau levels; implications for the role of microtubule dynamics in regulating tau expression

por Dickey, Chad A, Ash, Peter, Klosak, Natalia, Lee, Wing C, Petrucelli, Leonard, Hutton, Michael, Eckman, Christopher B
Publicado 2006

Exploiting the Diversity of the Heat-Shock Protein Family for Primary and Secondary Tauopathy Therapeutics

por Abisambra, Jose F, Jinwal, Umesh K, Jones, Jeffrey R, Blair, Laura J, Koren, John, Dickey, Chad A
Publicado 2011

Dysregulation of Na+/K+ ATPase by amyloid in APP+PS1 transgenic mice

por Dickey, Chad A, Gordon, Marcia N, Wilcock, Donna M, Herber, Donna L, Freeman, Melissa J, Morgan, Dave
Publicado 2005

Hippocampal Neurogenesis Is Enhanced in Adult Tau Deficient Mice

por Criado-Marrero, Marangelie, Sabbagh, Jonathan J., Jones, Margaret R., Chaput, Dale, Dickey, Chad A., Blair, Laura J.
Publicado 2020

The Disease-Associated Chaperone FKBP51 Impairs Cognitive Function by Accelerating AMPA Receptor Recycling

por Blair, Laura J., Criado-Marrero, Marangelie, Zheng, Dali, Wang, Xinming, Kamath, Siddharth, Nordhues, Bryce A., Weeber, Edwin J., Dickey, Chad A.
Publicado 2019

Early Life Stress and High FKBP5 Interact to Increase Anxiety-Like Symptoms through Altered AKT Signaling in the Dorsal Hippocampus

por Criado-Marrero, Marangelie, Gebru, Niat T., Gould, Lauren A., Smith, Taylor M., Kim, Sojeong, Blackburn, Roy J., Dickey, Chad A., Blair, Laura J.
Publicado 2019

Chaperone signalling complexes in Alzheimer's disease

por Koren, John, Jinwal, Umesh K, Lee, Daniel C, Jones, Jeffrey R, Shults, Cody L, Johnson, Amelia G, Anderson, Laura J, Dickey, Chad A
Publicado 2009

Age-Associated Epigenetic Upregulation of the FKBP5 Gene Selectively Impairs Stress Resiliency

por Sabbagh, Jonathan J., O'Leary, John C., Blair, Laura J., Klengel, Torsten, Nordhues, Bryce A., Fontaine, Sarah N., Binder, Elisabeth B., Dickey, Chad A.
Publicado 2014

FKBP5 and early life stress affect the hippocampus by an age-dependent mechanism

por Criado-Marrero, Marangelie, Smith, Taylor M., Gould, Lauren A., Kim, Sojeong, Penny, Hannah J., Sun, Zheying, Gulick, Danielle, Dickey, Chad A., Blair, Laura J.
Publicado 2020

LPS- induced inflammation exacerbates phospho-tau pathology in rTg4510 mice

por Lee, Daniel C, Rizer, Justin, Selenica, Maj-Linda B, Reid, Patrick, Kraft, Clara, Johnson, Amelia, Blair, Laura, Gordon, Marcia N, Dickey, Chad A, Morgan, Dave
Publicado 2010

Rhodacyanine Derivative Selectively Targets Cancer Cells and Overcomes Tamoxifen Resistance

por Koren, John, Miyata, Yoshinari, Kiray, Janine, O'Leary, John C., Nguyen, Lana, Guo, Jianping, Blair, Laura J., Li, Xiokai, Jinwal, Umesh K., Cheng, Jin Q., Gestwicki, Jason E., Dickey, Chad A.
Publicado 2012

Correction: Rhodacyanine Derivative Selectively Targets Cancer Cells and Overcomes Tamoxifen Resistance

por Koren, John, Miyata, Yoshinari, Kiray, Janine, O'Leary, John C., Nguyen, Lana, Guo, Jianping, Blair, Laura J., Li, Xiaokai, Jinwal, Umesh K., Cheng, Jin Q., Gestwicki, Jason E., Dickey, Chad A.
Publicado 2012

Tau depletion prevents progressive blood-brain barrier damage in a mouse model of tauopathy

por Blair, Laura J, Frauen, Haley D, Zhang, Bo, Nordhues, Bryce A, Bijan, Sara, Lin, Yen-Chi, Zamudio, Frank, Hernandez, Lidice D, Sabbagh, Jonathan J, Selenica, Maj-Linda B, Dickey, Chad A
Publicado 2015

A New Anti-Depressive Strategy for the Elderly: Ablation of FKBP5/FKBP51

por O'Leary, John C., Dharia, Sheetal, Blair, Laura J., Brady, Sarah, Johnson, Amelia G., Peters, Melinda, Cheung-Flynn, Joyce, Cox, Marc B., de Erausquin, Gabriel, Weeber, Edwin J., Jinwal, Umesh K., Dickey, Chad A.
Publicado 2011

Epitope analysis following active immunization with tau proteins reveals immunogens implicated in tau pathogenesis

por Selenica, Maj-Linda B, Davtyan, Hayk, Housley, Steven B, Blair, Laura J, Gillies, Anne, Nordhues, Bryce A, Zhang, Bo, Liu, Joseph, Gestwicki, Jason E, Lee, Daniel C, Gordon, Marcia N, Morgan, Dave, Dickey, Chad A
Publicado 2014

Structure and pro-toxic mechanism of the human Hsp90/PPIase/Tau complex

por Oroz, Javier, Chang, Bliss J., Wysoczanski, Piotr, Lee, Chung-Tien, Pérez-Lara, Ángel, Chakraborty, Pijush, Hofele, Romina V., Baker, Jeremy D., Blair, Laura J., Biernat, Jacek, Urlaub, Henning, Mandelkow, Eckhard, Dickey, Chad A., Zweckstetter, Markus
Publicado 2018

FKBP52 overexpression accelerates hippocampal-dependent memory impairments in a tau transgenic mouse model

por Criado-Marrero, Marangelie, Gebru, Niat T., Gould, Lauren A., Blazier, Danielle M., Vidal-Aguiar, Yamile, Smith, Taylor M., Abdelmaboud, Salma S., Shelton, Lindsey B., Wang, Xinming, Dahrendorff, Jan, Beaulieu-Abdelahad, David, Dickey, Chad A., Blair, Laura J.
Publicado 2021

Hsp22 with an N-Terminal Domain Truncation Mediates a Reduction in Tau Protein Levels

por Webster, Jack M., Darling, April L., Sanders, Taylor A., Blazier, Danielle M., Vidal-Aguiar, Yamile, Beaulieu-Abdelahad, David, Plemmons, Drew G., Hill, Shannon E., Uversky, Vladimir N., Bickford, Paula C., Dickey, Chad A., Blair, Laura J.
Publicado 2020