Identification of unusual oxysterols biosynthesised in human pregnancy by charge-tagging and liquid chromatography - mass spectrometry

por Dickson, Alison L., Yutuc, Eylan, Thornton, Catherine A., Wang, Yuqin, Griffiths, William J.
Publicado 2022

Human 2′-Deoxynucleoside 5′-Phosphate N-Hydrolase 1: Mechanism of 2′-Deoxyuridine 5′-Monophosphate Hydrolysis

por Devi, Suneeta, Carberry, Anna E., Zickuhr, Greice M., Dickson, Alison L., Harrison, David J., da Silva, Rafael G.
Publicado 2023

Catalytic Cycle of the Bifunctional Enzyme Phosphoribosyl-ATP Pyrophosphohydrolase/Phosphoribosyl-AMP Cyclohydrolase

por Fisher, Gemma, Pečaver, Ennio, Read, Benjamin J., Leese, Susannah K., Laing, Erin, Dickson, Alison L., Czekster, Clarissa M., da Silva, Rafael G.
Publicado 2023

The novel anti-cancer fluoropyrimidine NUC-3373 is a potent inhibitor of thymidylate synthase and an effective DNA-damaging agent

por Bré, Jennifer, Dickson, Alison L., Read, Oliver J., Zhang, Ying, McKissock, Fiona G., Mullen, Peter, Tang, Peijun, Zickuhr, Greice M., Czekster, Clarissa M., Harrison, David J.
Publicado 2023

Deep mining of oxysterols and cholestenoic acids in human plasma and cerebrospinal fluid: Quantification using isotope dilution mass spectrometry

por Yutuc, Eylan, Dickson, Alison L., Pacciarini, Manuela, Griffiths, Lauren, Baker, Paul R.S., Connell, Lisa, Öhman, Anders, Forsgren, Lars, Trupp, Miles, Vilarinho, Sílvia, Khalil, Youssef, Clayton, Peter T., Sari, Sinan, Dalgic, Buket, Höflinger, Philip, Schöls, Ludger, Griffiths, William J., Wang, Yuqin
Publicado 2021

Bile acid biosynthesis in Smith-Lemli-Opitz syndrome bypassing cholesterol: Potential importance of pathway intermediates

por Abdel-Khalik, Jonas, Hearn, Thomas, Dickson, Alison L., Crick, Peter J., Yutuc, Eylan, Austin-Muttitt, Karl, Bigger, Brian W., Morris, Andrew A., Shackleton, Cedric H., Clayton, Peter T., Iida, Takashi, Sircar, Ria, Rohatgi, Rajat, Marschall, Hanns-Ulrich, Sjövall, Jan, Björkhem, Ingemar, Mullins, Jonathan G.L., Griffiths, William J., Wang, Yuqin
Publicado 2021