The finger loop of the SRA domain in the E3 ligase UHRF1 is a regulator of ubiquitin targeting and is required for the maintenance of DNA methylation

por Vaughan, Robert M., Rothbart, Scott B., Dickson, Bradley M.
Publicado 2019

Analysis of histone antibody specificity directly in sequencing data using siQ-ChIP

por Kupai, Ariana, Vaughan, Robert M., Rothbart, Scott B., Dickson, Bradley M.
Publicado 2023

Streamlined quantitative analysis of histone modification abundance at nucleosome-scale resolution with siQ-ChIP version 2.0

por Dickson, Bradley M., Kupai, Ariana, Vaughan, Robert M., Rothbart, Scott B.
Publicado 2023

A Degenerate Peptide Library Approach to Reveal Sequence Determinants of Methyllysine-Driven Protein Interactions

por Kupai, Ariana, Vaughan, Robert M., Dickson, Bradley M., Rothbart, Scott B.
Publicado 2020

Comparative biochemical analysis of UHRF proteins reveals molecular mechanisms that uncouple UHRF2 from DNA methylation maintenance

por Vaughan, Robert M, Dickson, Bradley M, Cornett, Evan M, Harrison, Joseph S, Kuhlman, Brian, Rothbart, Scott B
Publicado 2018

A physical basis for quantitative ChIP-sequencing

por Dickson, Bradley M., Tiedemann, Rochelle L., Chomiak, Alison A., Cornett, Evan M., Vaughan, Robert M., Rothbart, Scott B.
Publicado 2020

Molecular mechanisms of fentanyl mediated β-arrestin biased signaling

por de Waal, Parker W., Shi, Jingjing, You, Erli, Wang, Xiaoxi, Melcher, Karsten, Jiang, Yi, Xu, H. Eric, Dickson, Bradley M.
Publicado 2020

DNA strand asymmetry generated by CpG hemimethylation has opposing effects on CTCF binding

por Thomas, Stacey L, Xu, Ting-Hai, Carpenter, Brittany L, Pierce, Steven E, Dickson, Bradley M, Liu, Minmin, Liang, Gangning, Jones, Peter A
Publicado 2023

Global lysine methylome profiling using systematically characterized affinity reagents

por Berryhill, Christine A., Hanquier, Jocelyne N., Doud, Emma H., Cordeiro-Spinetti, Eric, Dickson, Bradley M., Rothbart, Scott B., Mosley, Amber L., Cornett, Evan M.
Publicado 2023

Chromatin structure and its chemical modifications regulate the ubiquitin ligase substrate selectivity of UHRF1

por Vaughan, Robert M., Dickson, Bradley M., Whelihan, Matthew F., Johnstone, Andrea L., Cornett, Evan M., Cheek, Marcus A., Ausherman, Christine A., Cowles, Martis W., Sun, Zu-Wen, Rothbart, Scott B.
Publicado 2018

The structural basis of the dominant negative phenotype of the Gα(i1)β(1)γ(2) G203A/A326S heterotrimer

por Liu, Ping, Jia, Ming-zhu, Zhou, X Edward, De Waal, Parker W, Dickson, Bradley M, Liu, Bo, Hou, Li, Yin, Yan-ting, Kang, Yan-yong, Shi, Yi, Melcher, Karsten, Xu, H Eric, Jiang, Yi
Publicado 2016

A functional proteomics platform to reveal the sequence determinants of lysine methyltransferase substrate selectivity

por Cornett, Evan M., Dickson, Bradley M., Krajewski, Krzysztof, Spellmon, Nicholas, Umstead, Andrew, Vaughan, Robert M., Shaw, Kevin M., Versluis, Philip P., Cowles, Martis W., Brunzelle, Joseph, Yang, Zhe, Vega, Irving E., Sun, Zu-Wen, Rothbart, Scott B.
Publicado 2018

The histone and non-histone methyllysine reader activities of the UHRF1 tandem Tudor domain are dispensable for the propagation of aberrant DNA methylation patterning in cancer cel...

por Vaughan, Robert M., Kupai, Ariana, Foley, Caroline A., Sagum, Cari A., Tibben, Bailey M., Eden, Hope E., Tiedemann, Rochelle L., Berryhill, Christine A., Patel, Varun, Shaw, Kevin M., Krajewski, Krzysztof, Strahl, Brian D., Bedford, Mark T., Frye, Stephen V., Dickson, Bradley M., Rothbart, Scott B.
Publicado 2020

Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1

por Harrison, Joseph S, Cornett, Evan M, Goldfarb, Dennis, DaRosa, Paul A, Li, Zimeng M, Yan, Feng, Dickson, Bradley M, Guo, Angela H, Cantu, Daniel V, Kaustov, Lilia, Brown, Peter J, Arrowsmith, Cheryl H, Erie, Dorothy A, Major, Michael B, Klevit, Rachel E, Krajewski, Krzysztof, Kuhlman, Brian, Strahl, Brian D, Rothbart, Scott B
Publicado 2016

A cellular chemical probe targeting the chromodomains of Polycomb Repressive Complex 1

por Stuckey, Jacob I, Dickson, Bradley M, Cheng, Nancy, Liu, Yanli, Norris, Jacqueline L, Cholensky, Stephanie H, Tempel, Wolfram, Qin, Su, Huber, Katherine G, Sagum, Cari, Black, Karynne, Li, Fengling, Huang, Xi-Ping, Roth, Bryan L, Baughman, Brandi M, Senisterra, Guillermo, Pattenden, Samantha G, Vedadi, Masoud, Brown, Peter J, Bedford, Mark T, Min, Jinrong, Arrowsmith, Cheryl H, James, Lindsey I, Frye, Stephen V
Publicado 2016