Structural basis for catalysis and substrate specificity of a 3C-like cysteine protease from a mosquito mesonivirus

por Kanitz, Manuel, Blanck, Sandra, Heine, Andreas, Gulyaeva, Anastasia A., Gorbalenya, Alexander E., Ziebuhr, John, Diederich, Wibke E.
Publicado 2019

PPARβ/δ recruits NCOR and regulates transcription reinitiation of ANGPTL4

por Legrand, Nathalie, Bretscher, Clemens L, Zielke, Svenja, Wilke, Bernhard, Daude, Michael, Fritz, Barbara, Diederich, Wibke E, Adhikary, Till
Publicado 2019

Which Properties Allow Ligands to Open and Bind to the Transient Binding Pocket of Human Aldose Reductase?

por Sandner, Anna, Ngo, Khang, Sager, Christoph P., Scheer, Frithjof, Daude, Michael, Diederich, Wibke E., Heine, Andreas, Klebe, Gerhard
Publicado 2021

Identification of inhibitors of the transmembrane protease FlaK of Methanococcus maripaludis

por Coburger, Ina, Schaub, Yvonne, Roeser, Dirk, Hardes, Kornelia, Maeder, Patrick, Klee, Nina, Steinmetzer, Torsten, Imhof, Diana, Diederich, Wibke E., Than, Manuel E.
Publicado 2016

The Bacterial Product Violacein Exerts an Immunostimulatory Effect Via TLR8

por Venegas, Francisco A., Köllisch, Gabriele, Mark, Kerstin, Diederich, Wibke E., Kaufmann, Andreas, Bauer, Stefan, Chavarría, Max, Araya, Juan J., García-Piñeres, Alfonso J.
Publicado 2019

Tumor-suppressive disruption of cancer subtype-associated super enhancer circuits by small molecule treatment

por Koeniger, Anke, Polo, Pierfrancesco, Brichkina, Anna, Finkernagel, Florian, Visekruna, Alexander, Nist, Andrea, Stiewe, Thorsten, Daude, Michael, Diederich, Wibke E, Gress, Thomas M, Adhikary, Till, Lauth, Matthias
Publicado 2023

The transcriptional PPARβ/δ network in human macrophages defines a unique agonist-induced activation state

por Adhikary, Till, Wortmann, Annika, Schumann, Tim, Finkernagel, Florian, Lieber, Sonja, Roth, Katrin, Toth, Philipp M., Diederich, Wibke E., Nist, Andrea, Stiewe, Thorsten, Kleinesudeik, Lara, Reinartz, Silke, Müller-Brüsselbach, Sabine, Müller, Rolf
Publicado 2015

Deregulation of PPARβ/δ target genes in tumor-associated macrophages by fatty acid ligands in the ovarian cancer microenvironment

por Schumann, Tim, Adhikary, Till, Wortmann, Annika, Finkernagel, Florian, Lieber, Sonja, Schnitzer, Evelyn, Legrand, Nathalie, Schober, Yvonne, Nockher, W. Andreas, Toth, Philipp M., Diederich, Wibke E., Nist, Andrea, Stiewe, Thorsten, Wagner, Uwe, Reinartz, Silke, Müller-Brüsselbach, Sabine, Müller, Rolf
Publicado 2015

Native metabolomics identifies the rivulariapeptolide family of protease inhibitors

por Reher, Raphael, Aron, Allegra T., Fajtová, Pavla, Stincone, Paolo, Wagner, Berenike, Pérez-Lorente, Alicia I., Liu, Chenxi, Shalom, Ido Y. Ben, Bittremieux, Wout, Wang, Mingxun, Jeong, Kyowon, Matos-Hernandez, Marie L., Alexander, Kelsey L., Caro-Diaz, Eduardo J., Naman, C. Benjamin, Scanlan, J. H. William, Hochban, Phil M. M., Diederich, Wibke E., Molina-Santiago, Carlos, Romero, Diego, Selim, Khaled A., Sass, Peter, Brötz-Oesterhelt, Heike, Hughes, Chambers C., Dorrestein, Pieter C., O’Donoghue, Anthony J., Gerwick, William H., Petras, Daniel
Publicado 2022