Inhibition of CD73 AMP hydrolysis by a therapeutic antibody with a dual, non-competitive mechanism of action

por Geoghegan, James C., Diedrich, Gundo, Lu, Xiaojun, Rosenthal, Kim, Sachsenmeier, Kris F., Wu, Herren, Dall'Acqua, William F., Damschroder, Melissa M.
Publicado 2016

Redirection of Cord Blood T Cells and Natural Killer Cells for Elimination of Autologous HIV-1-Infected Target Cells Using Bispecific DART® Molecules

por Pollara, Justin, Edwards, R. Whitney, Jha, Shalini, Lam, Chia-Ying Kao, Liu, Liqin, Diedrich, Gundo, Nordstrom, Jeffrey L., Huffman, Tori, Pickeral, Joy A., Denny, Thomas N., Permar, Sallie R., Ferrari, Guido
Publicado 2020

Targeting CD73 in the tumor microenvironment with MEDI9447

por Hay, Carl M., Sult, Erin, Huang, Qihui, Mulgrew, Kathy, Fuhrmann, Stacy R., McGlinchey, Kelly A., Hammond, Scott A., Rothstein, Raymond, Rios-Doria, Jonathan, Poon, Edmund, Holoweckyj, Nick, Durham, Nicholas M., Leow, Ching Ching, Diedrich, Gundo, Damschroder, Melissa, Herbst, Ronald, Hollingsworth, Robert E., Sachsenmeier, Kris F.
Publicado 2016

Development and Preliminary Clinical Activity of PD-1-Guided CTLA-4 Blocking Bispecific DART Molecule

por Berezhnoy, Alexey, Sumrow, Bradley J., Stahl, Kurt, Shah, Kalpana, Liu, Daorong, Li, Jonathan, Hao, Su-Shin, De Costa, Anushka, Kaul, Sanjeev, Bendell, Johanna, Cote, Gregory M., Luke, Jason J., Sanborn, Rachel E., Sharma, Manish R., Chen, Francine, Li, Hua, Diedrich, Gundo, Bonvini, Ezio, Moore, Paul A.
Publicado 2020