Diet-induced obesity alters the differentiation potential of stem cells isolated from bone marrow, adipose tissue, and infrapatellar fad pad: The effects of free fatty acids

por Wu, Chia-Lung, Diekman, Brian O’Callaghan, Jain, Deeptee, Guilak, Farshid
Publicado 2012

Comet assay for quantification of the increased DNA damage burden in primary human chondrocytes with aging and osteoarthritis

por Copp, Michaela E., Chubinskaya, Susan, Bracey, Daniel N., Shine, Jacqueline, Sessions, Garrett, Loeser, Richard F., Diekman, Brian O.
Publicado 2022

SIRT6 activation rescues the age-related decline in DNA damage repair in primary human chondrocytes

por Copp, Michaela E., Shine, Jacqueline, Brown, Hannon L., Nimmala, Kirti R., Chubinskaya, Susan, Collins, John A., Loeser, Richard F., Diekman, Brian O.
Publicado 2023

Expression of p16(INK) (4a) is a biomarker of chondrocyte aging but does not cause osteoarthritis

por Diekman, Brian O., Sessions, Garrett A., Collins, John A., Knecht, Anne K., Strum, Susan L., Mitin, Natalia K., Carlson, Cathy S., Loeser, Richard F., Sharpless, Norman E.
Publicado 2018

Long-term treatment with senolytic drugs Dasatinib and Quercetin ameliorates age-dependent intervertebral disc degeneration in mice

por Novais, Emanuel J., Tran, Victoria A., Johnston, Shira N., Darris, Kayla R., Roupas, Alex J., Sessions, Garrett A., Shapiro, Irving M., Diekman, Brian O., Risbud, Makarand V.
Publicado 2021

Cells exhibiting strong p16(INK4a) promoter activation in vivo display features of senescence

por Liu, Jie-Yu, Souroullas, George P., Diekman, Brian O., Krishnamurthy, Janakiraman, Hall, Brandon M., Sorrentino, Jessica A., Parker, Joel S., Sessions, Garrett A., Gudkov, Andrei V., Sharpless, Norman E.
Publicado 2019